      Product Title: N-Acetyl Selank Amidate X20mg

      URL handle: n-acetyl-selank-amidate-20mg-biolongevity-labs

      SKU: NASEL-20MG

      Brand: Biolongevity Labs

      Current URL: https://fmihealth.com/products/n-acetyl-selank-amidate-20mg-biolongevity-labs

      Meta Title: N-Acetyl Selank Amidate X20mg

      Meta Description: Description--Selank is a synthetic heptapeptide (Thr‑Lys‑Pro‑Arg‑Pro‑Gly‑Pro) derived from the natural regulatory peptide tuftsin. It is primarily studied for its anxiolytic (anti‑anxiety), nootropic (cognitive‑enhancing), immunomodulatory, and antiviral properties. Its activity is linked to modulation of the GABAergic

      Health Conditions: Anxiety | Cognitive Function | Stress Resilience



      Description HTML:

      <p>Description--<!--StartFragment -->Selank is a synthetic heptapeptide (Thr‑Lys‑Pro‑Arg‑Pro‑Gly‑Pro) derived from the natural regulatory peptide tuftsin. It is primarily studied for its anxiolytic (anti‑anxiety), nootropic (cognitive‑enhancing), immunomodulatory, and antiviral properties. Its activity is linked to modulation of the GABAergic system and influence on gene expression.</p>
<p> </p>
<p>N‑Acetyl Selank Amidate is a modified version of Selank, engineered through N‑terminal acetylation and C‑terminal amidation. These structural modifications enhance stability, potency, and blood‑brain barrier penetration, extending biological activity compared to standard Selank.</p>
<p> </p>
<p><strong>Mechanistic Claims</strong></p>
<ul>
<li>
<strong>GABAergic Modulation:</strong> Influences GABA receptor activity, contributing to anxiolytic effects.</li>
<li>
<strong>Gene Expression Regulation:</strong> Alters transcriptional activity linked to stress response and cognition.</li>
<li>
<strong>Neuroprotective Effects:</strong> Supports resilience against stress‑induced neuronal changes.</li>
<li>
<strong>Enhanced Stability:</strong> Acetylation and amidation confer resistance to enzymatic degradation.</li>
<li>
<strong>Improved Bioavailability:</strong> Structural modifications increase potency and CNS penetration.</li>
</ul>
<p> </p>
<p><strong>Research Applications</strong></p>
<ul>
<li>Anxiety and stress‑related disorder models</li>
<li>Cognitive enhancement and memory studies</li>
<li>Immunomodulation and antiviral research</li>
<li>Neuroprotection and resilience investigations</li>
<li>Exploratory therapeutic studies in mood regulation and psychiatric conditions</li>
</ul>
<p> </p>
<p><strong>N‑Acetyl Selank Amidate Research Insights</strong></p>
<ul>
<li>Synthetic heptapeptide derived from tuftsin, with anxiolytic and cognitive‑enhancing properties.</li>
<li>Modified through acetylation and amidation for improved pharmacological profile.</li>
<li>Demonstrates enhanced stability and potency compared to standard Selank.</li>
<li>Preclinical studies highlight roles in anxiety reduction, cognitive support, and immune modulation.</li>
<li>Investigated for therapeutic potential in stress‑related disorders, neuroprotection, and antiviral activity.</li>
</ul>
<p><!--EndFragment --><br></p>
<p><strong>N-Acetyl Selank Research</strong></p>
<p>Selank is a multifaceted peptide with significant potential in treating anxiety, cognitive impairments, and stress-related physiological changes. Its ability to modulate the GABAergic system, enhance cognitive function, and exert immunomodulatory effects positions it as a versatile therapeutic agent.</p>
<p class="mt-6 mb-3 base-bold"> </p>
<p class="mt-6 mb-3 base-bold"><em><strong>Anxiolytic and Cognitive Effects</strong></em></p>
<p class="markdown-p">Selank has demonstrated significant anxiolytic properties, comparable to classical benzodiazepines, without the associated side effects such as dependence and memory <span class="whitespace-nowrap">impairment<sup>1</sup>. It has been shown to reduce anxiety in conditions of chronic stress and improve cognitive functions, such as memory and attention, particularly in the context of ethanol-induced impairments. The peptide’s ability to regulate brain-derived neurotrophic factor (BDNF) content in the hippocampus and prefrontal cortex is thought to contribute to its cognitive-enhancing effects<sup>2</sup>.</span></p>
<p class="mt-6 mb-3 base-bold"> </p>
<p class="mt-6 mb-3 base-bold"><em><strong>Immunomodulatory and Antiviral Properties</strong></em></p>
<p class="markdown-p">Beyond its neurological effects, Selank also exhibits immunomodulatory and antiviral properties. It can significantly alter the expression of genes related to chemokines, cytokines, and their receptors, suggesting a role in immune response <span class="whitespace-nowrap">modulation<sup>3</sup>. These properties make Selank a promising candidate for therapeutic applications beyond anxiety and cognitive disorders.</span></p>
<p class="mt-6 mb-3 base-bold"> </p>
<p class="mt-6 mb-3 base-bold"><em><strong>Stress Mitigation and Physiological Effects</strong></em></p>
<p class="markdown-p">Selank has been shown to mitigate stress-induced physiological changes. In animal models, it reduces stress-related morphological changes in organs such as the liver and colon, indicating its potential to alleviate stress-induced <span class="whitespace-nowrap">damage. These effects are likely due to its multifunctional biological activity, which includes reducing corticosterone levels and promoting adaptation to stress<sup>4</sup>.</span></p>
<p> </p>
<p><strong>References</strong></p>
<ol>
<li>
<p>Vyunova, T., Andreeva, L., Shevchenko, K., &amp; Myasoedov, N. (2018). Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity.. <em>Protein and peptide letters</em>, 25 10, 914-923 . <a href="https://doi.org/10.2174/0929866525666180925144642" rel="noopener" target="_blank">https://doi.org/10.2174/0929866525666180925144642</a>.</p>
</li>
<li>
<p>Kolik, L., Nadorova, A., Antipova, T., Kruglov, S., Kudrin, V., &amp; Durnev, A. (2019). Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats. <em>Bulletin of Experimental Biology and Medicine</em>, 167, 641 – 644. <a href="https://doi.org/10.1007/s10517-019-04588-9" rel="noopener" target="_blank">https://doi.org/10.1007/s10517-019-04588-9</a>.</p>
</li>
<li>
<p>Kolomin, T., Mikhalskaia, P., &amp; Sedelnikova, A. (2023). Changes in Expression of Chemokines, Cytokines and their Receptors under the Action of Selank and its Fragments. <em>Journal of Clinical Physiology and Pathology</em>. <a href="https://doi.org/10.59315/jiscpp.2023-2-2.16-18" rel="noopener" target="_blank">https://doi.org/10.59315/jiscpp.2023-2-2.16-18</a>.</p>
</li>
<li>
<p>Mukhina, A., Mishina, E., Bobyntsev, I., Medvedeva, O., Svishcheva, M., Kalutskiĭ, P., Andreeva, L., &amp; Myasoedov, N. (2020). Morphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank. <em>Bulletin of Experimental Biology and Medicine</em>, 169, 281 – 285. <a href="https://doi.org/10.1007/s10517-020-04868-9" rel="noopener" target="_blank">https://doi.org/10.1007/s10517-020-04868-9</a>.</p>
</li>
</ol>
<p><br>Label--<strong>Peptide Information</strong></p>
<table class="bg-bg-100 min-w-full border-separate border-spacing-0 text-sm leading-[1.88888] whitespace-normal" style="width: 99.9363%;">
<thead class="border-b-border-100/50 border-b-[0.5px] text-left">
<tr class="[tbody&gt;&amp;]:odd:bg-bg-500/10">
<th class="text-text-000 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 27.9556%;">Property</th>
<th class="text-text-000 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 71.5313%;">Value</th>
</tr>
</thead>
<tbody>
<tr class="[tbody&gt;&amp;]:odd:bg-bg-500/10">
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 27.9556%;">Peptide Sequence</td>
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 71.5313%;">Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2</td>
</tr>
<tr class="[tbody&gt;&amp;]:odd:bg-bg-500/10">
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 27.9556%;">Molecular Formula</td>
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 71.5313%;">C33H57N11O9</td>
</tr>
<tr class="[tbody&gt;&amp;]:odd:bg-bg-500/10">
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 27.9556%;">Molecular Weight</td>
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 71.5313%;">751.9 g/mol</td>
</tr>
<tr class="[tbody&gt;&amp;]:odd:bg-bg-500/10">
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 27.9556%;">CAS Number</td>
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 71.5313%;">129954-34-3</td>
</tr>
<tr class="[tbody&gt;&amp;]:odd:bg-bg-500/10">
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 27.9556%;">PubChem CID</td>
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 71.5313%;">11765600</td>
</tr>
<tr class="[tbody&gt;&amp;]:odd:bg-bg-500/10">
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 27.9556%;">Synonyms</td>
<td class="border-t-border-100/50 [&amp;:not(:first-child)]:-x-[hsla(var(--border-100) / 0.5)] border-t-[0.5px] px-2 [&amp;:not(:first-child)]:border-l-[0.5px]" style="width: 71.5313%;">Selank, 129954-34-3, Selanc, Thr-Lys-Pro-Arg-Pro-Gly-Pro, TP-7</td>
</tr>
</tbody>
</table>
<p> </p>
<p><strong>N-Acetyl Selank Peptide Structure</strong></p>
<p><img data-opt-id="464834253" data-opt-src="https://www.peptidesciences.com/media/wysiwyg/Selank_Structure.png" decoding="async" class="" src="https://www.peptidesciences.com/media/wysiwyg/Selank_Structure.png" alt="Molecule" width="369" height="369" title="N-Acetyl Selank Amidate (20mg) 3" data-opt-lazy-loaded="true" data-opt-optimized-width="369" data-opt-optimized-height="369"></p>
<p>Source<span> </span><a href="https://pubchem.ncbi.nlm.nih.gov/compound/Selank" rel="noopener" target="_blank">PubChem</a></p>
<p> </p>
<p>Dosage--<strong>This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.</strong><span> This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.</span></p>
    

      
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N-Acetyl Selank Amidate X20mg

Biolongevity Labs

Anxiety | Cognitive Function | Stress Resilience

Rs. 15,697

Unit price: per

100% Authentic

Made in USA

Authorised distributor

1-5 Days delivery

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N-Acetyl Selank Amidate X 20mg

Name: N-Acetyl Selank Amidate X20mg
Brand: Biolongevity Labs
SKU: NASEL-20MG
Price: 15697.0 INR
Availability: InStock

Anxiety | Cognitive Function | Stress Resilience

Biolongevity Labs

Rs. 15,697

Unit price: per

No Reviews

Rs. 15,697

Unit price: per

Price includes all duties and taxes

SKU: NASEL-20MG FMI's Choice

About the Product

N-Acetyl Selank Amidate Research Peptide: Stabilized synthetic heptapeptide for preclinical studies on anxiolytic effects, cognitive enhancement, neuroprotection, and immune modulation.
GABAergic & Gene Modulation: Modulates the GABAergic system and influences gene expression, supporting studies on anxiety regulation, stress response, and neurocognitive pathways in laboratory models.
N-Terminal Acetylation: N-acetyl modification improves peptide stability, potency, and blood-brain barrier penetration, enhancing experimental reproducibility and neuropharmacological effects.
Neurocognitive & Immunomodulatory Research Applications: Supports preclinical studies on anxiety, cognitive function, stress resilience, immune regulation, and potential antiviral mechanisms.
Intended Use: For qualified researchers conducting controlled laboratory studies. Not for human or veterinary use.

Selank is a synthetic heptapeptide (Thr‑Lys‑Pro‑Arg‑Pro‑Gly‑Pro) derived from the natural regulatory peptide tuftsin. It is primarily studied for its anxiolytic (anti‑anxiety), nootropic (cognitive‑enhancing), immunomodulatory, and antiviral properties. Its activity is linked to modulation of the GABAergic system and influence on gene expression.

N‑Acetyl Selank Amidate is a modified version of Selank, engineered through N‑terminal acetylation and C‑terminal amidation. These structural modifications enhance stability, potency, and blood‑brain barrier penetration, extending biological activity compared to standard Selank.

Mechanistic Claims

GABAergic Modulation: Influences GABA receptor activity, contributing to anxiolytic effects.
Gene Expression Regulation: Alters transcriptional activity linked to stress response and cognition.
Neuroprotective Effects: Supports resilience against stress‑induced neuronal changes.
Enhanced Stability: Acetylation and amidation confer resistance to enzymatic degradation.
Improved Bioavailability: Structural modifications increase potency and CNS penetration.

Research Applications

Anxiety and stress‑related disorder models
Cognitive enhancement and memory studies
Immunomodulation and antiviral research
Neuroprotection and resilience investigations
Exploratory therapeutic studies in mood regulation and psychiatric conditions

N‑Acetyl Selank Amidate Research Insights

Synthetic heptapeptide derived from tuftsin, with anxiolytic and cognitive‑enhancing properties.
Modified through acetylation and amidation for improved pharmacological profile.
Demonstrates enhanced stability and potency compared to standard Selank.
Preclinical studies highlight roles in anxiety reduction, cognitive support, and immune modulation.
Investigated for therapeutic potential in stress‑related disorders, neuroprotection, and antiviral activity.

N-Acetyl Selank Research

Selank is a multifaceted peptide with significant potential in treating anxiety, cognitive impairments, and stress-related physiological changes. Its ability to modulate the GABAergic system, enhance cognitive function, and exert immunomodulatory effects positions it as a versatile therapeutic agent.

Anxiolytic and Cognitive Effects

Selank has demonstrated significant anxiolytic properties, comparable to classical benzodiazepines, without the associated side effects such as dependence and memory impairment¹. It has been shown to reduce anxiety in conditions of chronic stress and improve cognitive functions, such as memory and attention, particularly in the context of ethanol-induced impairments. The peptide’s ability to regulate brain-derived neurotrophic factor (BDNF) content in the hippocampus and prefrontal cortex is thought to contribute to its cognitive-enhancing effects².

Immunomodulatory and Antiviral Properties

Beyond its neurological effects, Selank also exhibits immunomodulatory and antiviral properties. It can significantly alter the expression of genes related to chemokines, cytokines, and their receptors, suggesting a role in immune response modulation³. These properties make Selank a promising candidate for therapeutic applications beyond anxiety and cognitive disorders.

Stress Mitigation and Physiological Effects

Selank has been shown to mitigate stress-induced physiological changes. In animal models, it reduces stress-related morphological changes in organs such as the liver and colon, indicating its potential to alleviate stress-induced damage. These effects are likely due to its multifunctional biological activity, which includes reducing corticosterone levels and promoting adaptation to stress⁴.

References

Vyunova, T., Andreeva, L., Shevchenko, K., & Myasoedov, N. (2018). Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity.. Protein and peptide letters, 25 10, 914-923 . https://doi.org/10.2174/0929866525666180925144642.
Kolik, L., Nadorova, A., Antipova, T., Kruglov, S., Kudrin, V., & Durnev, A. (2019). Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats. Bulletin of Experimental Biology and Medicine, 167, 641 – 644. https://doi.org/10.1007/s10517-019-04588-9.
Kolomin, T., Mikhalskaia, P., & Sedelnikova, A. (2023). Changes in Expression of Chemokines, Cytokines and their Receptors under the Action of Selank and its Fragments. Journal of Clinical Physiology and Pathology. https://doi.org/10.59315/jiscpp.2023-2-2.16-18.
Mukhina, A., Mishina, E., Bobyntsev, I., Medvedeva, O., Svishcheva, M., Kalutskiĭ, P., Andreeva, L., & Myasoedov, N. (2020). Morphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank. Bulletin of Experimental Biology and Medicine, 169, 281 – 285. https://doi.org/10.1007/s10517-020-04868-9.

Label--Peptide Information

Property	Value
Peptide Sequence	Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2
Molecular Formula	C33H57N11O9
Molecular Weight	751.9 g/mol
CAS Number	129954-34-3
PubChem CID	11765600
Synonyms	Selank, 129954-34-3, Selanc, Thr-Lys-Pro-Arg-Pro-Gly-Pro, TP-7

N-Acetyl Selank Peptide Structure

Molecule

Source PubChem

Dosage--This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.

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Made in USA

Authorised distributor

1 - 5 days delivery

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Product Information Sheet

Mechanistic Claims

GABAergic Modulation: Influences GABA receptor activity, contributing to anxiolytic effects.
Gene Expression Regulation: Alters transcriptional activity linked to stress response and cognition.
Neuroprotective Effects: Supports resilience against stress‑induced neuronal changes.
Enhanced Stability: Acetylation and amidation confer resistance to enzymatic degradation.
Improved Bioavailability: Structural modifications increase potency and CNS penetration.

Research Applications

Anxiety and stress‑related disorder models
Cognitive enhancement and memory studies
Immunomodulation and antiviral research
Neuroprotection and resilience investigations
Exploratory therapeutic studies in mood regulation and psychiatric conditions

N‑Acetyl Selank Amidate Research Insights

Synthetic heptapeptide derived from tuftsin, with anxiolytic and cognitive‑enhancing properties.
Modified through acetylation and amidation for improved pharmacological profile.
Demonstrates enhanced stability and potency compared to standard Selank.
Preclinical studies highlight roles in anxiety reduction, cognitive support, and immune modulation.
Investigated for therapeutic potential in stress‑related disorders, neuroprotection, and antiviral activity.

N-Acetyl Selank Research

Anxiolytic and Cognitive Effects

Immunomodulatory and Antiviral Properties

Stress Mitigation and Physiological Effects

References

Vyunova, T., Andreeva, L., Shevchenko, K., & Myasoedov, N. (2018). Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity.. Protein and peptide letters, 25 10, 914-923 . https://doi.org/10.2174/0929866525666180925144642.
Kolik, L., Nadorova, A., Antipova, T., Kruglov, S., Kudrin, V., & Durnev, A. (2019). Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats. Bulletin of Experimental Biology and Medicine, 167, 641 – 644. https://doi.org/10.1007/s10517-019-04588-9.
Kolomin, T., Mikhalskaia, P., & Sedelnikova, A. (2023). Changes in Expression of Chemokines, Cytokines and their Receptors under the Action of Selank and its Fragments. Journal of Clinical Physiology and Pathology. https://doi.org/10.59315/jiscpp.2023-2-2.16-18.
Mukhina, A., Mishina, E., Bobyntsev, I., Medvedeva, O., Svishcheva, M., Kalutskiĭ, P., Andreeva, L., & Myasoedov, N. (2020). Morphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank. Bulletin of Experimental Biology and Medicine, 169, 281 – 285. https://doi.org/10.1007/s10517-020-04868-9.

Peptide Information

Property	Value
Peptide Sequence	Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2
Molecular Formula	C33H57N11O9
Molecular Weight	751.9 g/mol
CAS Number	129954-34-3
PubChem CID	11765600
Synonyms	Selank, 129954-34-3, Selanc, Thr-Lys-Pro-Arg-Pro-Gly-Pro, TP-7

N-Acetyl Selank Peptide Structure

Molecule

Source PubChem

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.