5‑Amino‑1MQ is a synthetic nicotinamide N‑methyltransferase (NNMT) inhibitor of interest for in vitro metabolic disease research. By blocking NNMT activity, it modulates intracellular NAD+ and SAM levels, influencing energy production, fat metabolism, and epigenetic regulation. This methylquinolinium derivative is studied as a research compound for understanding metabolic processes, mitochondrial function, and cellular longevity mechanisms.
Mechanistic Claims
- NNMT Inhibition: Blocks nicotinamide N‑methyltransferase, preventing NAD+ depletion.
- NAD+ & SAM Modulation: Alters cellular cofactor pools, impacting energy metabolism.
- Metabolic Regulation: Influences fat metabolism and weight‑related processes in preclinical models.
- Muscle Preservation: Studied for effects on muscle tissue resilience under metabolic stress.
- Mitochondrial Function: Explored for roles in supporting mitochondrial efficiency.
- Cellular Aging: Investigated for potential links to longevity and epigenetic regulation.
Research Applications
- Metabolic disease and obesity research
- NAD+ biology and cofactor regulation studies
- Muscle tissue preservation models
- Mitochondrial function and energy metabolism investigations
- Cellular aging and epigenetic modulation research
5‑Amino‑1MQ Research Insights
- Synthetic methylquinolinium derivative with NNMT inhibitory activity.
- Preclinical studies highlight roles in weight regulation, muscle preservation, and mitochondrial support.
- Provides a research tool for exploring NAD+ metabolism, fat regulation, and cellular aging pathways.
- Supplied in lyophilized, filler‑free form to preserve purity and stability.
- For research use only; not intended for therapeutic application.
Peptide Information
| Property | Value |
|---|---|
| Molecular Formula | C10H11N2 |
| Molecular Weight | 159.21 g/mol |
| PubChem CID | 950107 |
| Synonyms | 5-amino-1-methylquinolinium, SCHEMBL6403148, CHEMBL4116828, ZMJBCEIHNOWCMC-UHFFFAOYSA-O, STL196667 |
5-Amino-1MQ Peptide Structure
Source: PubChem
This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.