KLOW Blend (GHK-Cu, BPC-157, TB-500, KPV) X 80mg
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Rs. 30,658
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- per
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KLOW Blend (GHK-Cu, BPC-157, TB-500, KPV) X 80mg
Regular price
Rs. 30,658
- Unit price
- per
Price includes all duties and taxes
SKU: BPC-TB5-KPV-GHK-80MG
FMI's Choice
Laboratory Research Overview
Laboratory investigations highlight synergistic mechanisms across cellular repair, vascular formation, and inflammatory modulation—providing valuable tools for in vitro research applications.
Angiogenesis and Vascular Formation
- BPC-157: Upregulates VEGFR2 expression without altering VEGF-A levels, activating the VEGFR2–Akt–eNOS signaling cascade in endothelial cell cultures [1].
- GHK-Cu: At nanomolar concentrations, increased VEGF and bFGF expression by 230% in irradiated fibroblasts [2]; liposomal delivery enhanced HUVEC proliferation by 33.1% with elevated cell cycle protein expression [3].
- TB-500: Acts as a potent endothelial chemoattractant, stimulating 4–6-fold increases in HUVEC migration; activity observed at ~50 nM concentration via LKKTET sequence [4].
Tissue Repair and Regeneration
- GHK-Cu: Modulates ~31% of human genes (4,192 genes) with ≥50% expression changes, activating integrin-linked kinase pathways [5].
- BPC-157: Promotes regeneration via FAK–paxillin pathway activation, increasing phosphorylation of focal adhesion proteins [6].
- TB-500: Sequesters G-actin in a 1:1 ratio; rat wound models showed 42–61% increased reepithelialization with enhanced collagen deposition [7].
Collagen Synthesis and Extracellular Matrix
- GHK-Cu: Stimulates collagen synthesis at picomolar–nanomolar concentrations; increased decorin by 302% and glycosaminoglycan accumulation [8].
- BPC-157: Enhances collagen, reticulin, and vascular formation in animal models [9].
- TB-500: Promotes organized collagen deposition with anti-fibrotic properties, reducing myofibroblast formation [10].
Inflammatory Modulation
- GHK-Cu: Inhibits NF-κB p65 and p38 MAPK pathways, reducing ROS and cytokines TNF-α and IL-6 [2].
- BPC-157: Decreases TNF-α, IL-6, IL-1β, COX-2 expression, and myeloperoxidase activity [11].
- TB-500: Biphasic regulation—downregulates TNF-α (6.2-fold) and IL-6 (4.1-fold), while upregulating IL-10 (8.1-fold) [12].
- KPV: Inhibits NF-κB activation via IκB-α stabilization; reduces cytokine secretion in epithelial and macrophage cultures [13,14].
Neuroprotection and Neural Mechanisms
- GHK-Cu: Increases NGF and neurotrophins NT-3/NT-4; improved spatial memory in aging models [15].
- BPC-157: Modulates dopaminergic systems without direct receptor binding [16].
- TB-500: Provides neuroprotection via caspase-3 inhibition; promotes oligodendrocyte progenitor proliferation through p38 MAPK upregulation [17].
Cellular Migration and Proliferation
- TB-500: G-actin sequestration drives migration; photorelease studies show directional cell turning [7].
- GHK-Cu: Chemoattractant for macrophages, mast cells, and endothelial cells [18].
- BPC-157: Regulates migration via ERK1/2 phosphorylation; transcription factors c-Fos (4.99-fold), c-Jun (7.05-fold), Egr-1 (3.70-fold) upregulated [19].
- KPV: Promotes keratinocyte and fibroblast migration; increased viability in corneal epithelial cultures [20].
Wound Healing Mechanisms
- BPC-157: Accelerates repair phases including inflammation, collagen deposition, angiogenesis, and epithelial recovery [9].
- GHK-Cu: Enhances systemic and local remodeling; collagen dressings improved contraction and antioxidant levels [5].
- TB-500: Promotes organized repair with anti-scarring effects; increased wound contraction (11%) and reepithelialization (42–61%) [10].
- KPV: Accelerates mucosal and corneal healing; complete reepithelialization within 60 hours [14,20].
Oxidative Stress Response
- GHK-Cu: Reduces ROS, increases superoxide dismutase activity, quenches radicals [21].
- TB-500: Upregulates antioxidant enzymes Cu/Zn-SOD and catalase [11].
- BPC-157: Scavenges free radicals, normalizes NO and MDA levels, increases HO-1 and NOS-3 expression [11].
- KPV: Inhibits ROS in keratinocytes via ERK and p38 MAPK modulation [22].
Disclaimer: These peptides are intended strictly for in vitro research applications. They are not for human consumption or therapeutic use.
References
[1] M.-J. Hsieh et al., “Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation,” Springer Science and Business Media LLC, Nov. 2016. doi: 10.1007/s00109-016-1488-y. Available: https://doi.org/10.1007/s00109-016-1488-y
[2] Y. Dou, A. Lee, L. Zhu, J. Morton, and W. Ladiges, “The potential of GHK as an anti-aging peptide,” Ant Publishing, Mar. 2020. doi: 10.31491/apt.2020.03.014. Available: https://doi.org/10.31491/apt.2020.03.014
[3] X. Wang et al., “GHK‐Cu‐liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis,” Wiley, Apr. 2017. doi: 10.1111/wrr.12520. Available: https://doi.org/10.1111/wrr.12520
[4] K. M. Malinda, A. L. Goldstein, and H. K. Kueinman, “Thymosin β 4 stimulates directional migration of human umbilical vein endothelial cells,” Wiley, May 1997. doi: 10.1096/fasebj.11.6.9194528. Available: https://doi.org/10.1096/fasebj.11.6.9194528
[5] L. Pickart and A. Margolina, “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data,” MDPI AG, Jul. 2018. doi: 10.3390/ijms19071987. Available: https://doi.org/10.3390/ijms19071987
[6] C.-H. Chang, W.-C. Tsai, M.-S. Lin, Y.-H. Hsu, and J.-H. S. Pang, “The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration,” American Physiological Society, Mar. 2011. doi: 10.1152/japplphysiol.00945.2010. Available: https://doi.org/10.1152/japplphysiol.00945.2010
[7] B. Xue, C. Leyrat, J. M. Grimes, and R. C. Robinson, “Structural basis of thymosin-β4/profilin exchange leading to actin filament polymerization,” Proceedings of the National Academy of Sciences, Oct. 2014. doi: 10.1073/pnas.1412271111. Available: https://doi.org/10.1073/pnas.1412271111
[8] F.-X. Maquart, L. Pickart, M. Laurent, P. Gillery, J.-C. Monboisse, and J.-P. Borel, “Stimulation of collagen synthesis in fibroblast cultures by the tripeptide‐copper complex glycyl‐L‐histidyl‐L‐lysine‐Cu2+,” Wiley, Oct. 1988. doi: 10.1016/0014-5793(88)80509-x. Available: https://doi.org/10.1016/0014-5793(88)80509-x
[9] S. Seiwerth et al., “Stable Gastric Pentadecapeptide BPC 157 and Wound Healing,” Frontiers Media SA, Jun. 2021. doi: 10.3389/fphar.2021.627533. Available: https://doi.org/10.3389/fphar.2021.627533
[10] K. M. Malinda et al., “Thymosin beta4 accelerates wound healing.,” Journal of Investigative Dermatology, vol. 113 3, pp. 364–8, 1999.
[11] H. Demirtaş, A. Özer, A. K. Yıldırım, A. D. Dursun, Ş. C. Sezen, and M. Arslan, “Protective Effects of BPC 157 on Liver, Kidney, and Lung Distant Organ Damage in Rats with Experimental Lower-Extremity Ischemia–Reperfusion Injury,” MDPI AG, Feb. 2025. doi: 10.3390/medicina61020291. Available: https://doi.org/10.3390/medicina61020291
[12] M. A. Evans et al., “Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing,” Springer Science and Business Media LLC, Jul. 2013. doi: 10.1038/ncomms3081. Available: https://doi.org/10.1038/ncomms3081
[13] G. Dalmasso, L. Charrier–Hisamuddin, H. T. Thu Nguyen, Y. Yan, S. Sitaraman, and D. Merlin, “PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation,” Elsevier BV, Jan. 2008. doi: 10.1053/j.gastro.2007.10.026. Available: https://doi.org/10.1053/j.gastro.2007.10.026
[14] B. Xiao et al., “Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis,” Elsevier BV, Jul. 2017. doi: 10.1016/j.ymthe.2016.11.020. Available: https://doi.org/10.1016/j.ymthe.2016.11.020
[15] L. Pickart, J. M. Vasquez-Soltero, and A. Margolina, “The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging: Implications for Cognitive Health,” Hindawi Limited, 2012. doi: 10.1155/2012/324832. Available: https://doi.org/10.1155/2012/324832
[16] J. Vukojevic et al., “Pentadecapeptide BPC 157 and the central nervous system,” Medknow, 2022. doi: 10.4103/1673-5374.320969. Available: https://doi.org/10.4103/1673-5374.320969
[17] S. Kim, J. Choi, and J. Kwon, “Thymosin Beta 4 Protects Hippocampal Neuronal Cells against PrP (106–126) via Neurotrophic Factor Signaling,” MDPI AG, May 2023. doi: 10.3390/molecules28093920. Available: https://doi.org/10.3390/molecules28093920
[18] L. Pickart, J. M. Vasquez-Soltero, and A. Margolina, “GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration,” Wiley, 2015. doi: 10.1155/2015/648108. Available: https://doi.org/10.1155/2015/648108
[19] T. Huang et al., “Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro,” Informa UK Limited, Apr. 2015. doi: 10.2147/dddt.s82030. Available: https://doi.org/10.2147/dddt.s82030
[20] M. Böhm and T. Luger, “Are melanocortin peptides future therapeutics for cutaneous wound healing?,” Wiley, Feb. 2019. doi: 10.1111/exd.13887. Available: https://doi.org/10.1111/exd.13887
[21] S. Sharma, M. F. Anwar, A. Dinda, M. Singhal, and A. Malik, “In Vitro and in Vivo Studies of pH-Sensitive GHK-Cu-Incorporated Polyaspartic and Polyacrylic Acid Superabsorbent Polymer,” American Chemical Society (ACS), Nov. 2019. doi: 10.1021/acsomega.9b00655. Available: https://doi.org/10.1021/acsomega.9b00655
[22] J. Sung, S.-Y. Ju, S. Park, W.-K. Jung, J.-Y. Je, and S.-J. Lee, “Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK/NF-κB pathway,” Elsevier BV, Aug. 2025. doi: 10.1016/j.tice.2025.102837. Available: https://doi.org/10.1016/j.tice.2025.102837
Label--
| Property | GHK-Cu | BPC-157 | TB-500 | KPV |
|---|---|---|---|---|
| Sequence | Gly-His-Lys.Cu.xHAc | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser | Lys-Pro-Val |
| Molecular Formula | C₁₄H₂₃CuN₆O₄ | C₆₂H₉₈N₁₆O₂₂ | C₂₁₂H₃₅₀N₅₆O₇₈S | C₁₇H₃₂N₆O₄ |
| Molecular Weight | 401.91 g/mol | 1419.5 g/mol | 4963.55 g/mol | 384.48 g/mol |
| PubChem CID | 73587 | 9941957 | 16132341 | 125672 |
| CAS Number | 89030-95-5 | 137525-51-0 | 77591-33-4 | 67727-97-3 |
| Synonyms | Copper peptide GHK, Cu-GHK, NSC 661251 | PL-14736, Body-Protection Compound-157, Bepecin | Thymosin-β4 fragment 17-23, TB-500 acetate, Ac-LKKTETQ | α-MSH fragment (11–13), Tripeptide KPV, Ac-KPV-NH2 |
Lyophilized Peptides: Our peptides are supplied in a pure, freeze-dried form with no fillers, ensuring long-term stability and integrity during cold storage. Simply reconstitute with sterile solvent before use, and store aliquots at ≤ –20 °C to protect against repeated freeze–thaw cycles.
Dosage-- For Research Purposes Only
This content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides
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Made in USA
Authorised distributor
1 - 5 days delivery
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Disclaimer
Product Information Sheet
: Not a diet substitute. Seek Medical guidance if unsure before use.
Laboratory Research Overview
Laboratory investigations highlight synergistic mechanisms across cellular repair, vascular formation, and inflammatory modulation—providing valuable tools for in vitro research applications.
Angiogenesis and Vascular Formation
- BPC-157: Upregulates VEGFR2 expression without altering VEGF-A levels, activating the VEGFR2–Akt–eNOS signaling cascade in endothelial cell cultures [1].
- GHK-Cu: At nanomolar concentrations, increased VEGF and bFGF expression by 230% in irradiated fibroblasts [2]; liposomal delivery enhanced HUVEC proliferation by 33.1% with elevated cell cycle protein expression [3].
- TB-500: Acts as a potent endothelial chemoattractant, stimulating 4–6-fold increases in HUVEC migration; activity observed at ~50 nM concentration via LKKTET sequence [4].
Tissue Repair and Regeneration
- GHK-Cu: Modulates ~31% of human genes (4,192 genes) with ≥50% expression changes, activating integrin-linked kinase pathways [5].
- BPC-157: Promotes regeneration via FAK–paxillin pathway activation, increasing phosphorylation of focal adhesion proteins [6].
- TB-500: Sequesters G-actin in a 1:1 ratio; rat wound models showed 42–61% increased reepithelialization with enhanced collagen deposition [7].
Collagen Synthesis and Extracellular Matrix
- GHK-Cu: Stimulates collagen synthesis at picomolar–nanomolar concentrations; increased decorin by 302% and glycosaminoglycan accumulation [8].
- BPC-157: Enhances collagen, reticulin, and vascular formation in animal models [9].
- TB-500: Promotes organized collagen deposition with anti-fibrotic properties, reducing myofibroblast formation [10].
Inflammatory Modulation
- GHK-Cu: Inhibits NF-κB p65 and p38 MAPK pathways, reducing ROS and cytokines TNF-α and IL-6 [2].
- BPC-157: Decreases TNF-α, IL-6, IL-1β, COX-2 expression, and myeloperoxidase activity [11].
- TB-500: Biphasic regulation—downregulates TNF-α (6.2-fold) and IL-6 (4.1-fold), while upregulating IL-10 (8.1-fold) [12].
- KPV: Inhibits NF-κB activation via IκB-α stabilization; reduces cytokine secretion in epithelial and macrophage cultures [13,14].
Neuroprotection and Neural Mechanisms
- GHK-Cu: Increases NGF and neurotrophins NT-3/NT-4; improved spatial memory in aging models [15].
- BPC-157: Modulates dopaminergic systems without direct receptor binding [16].
- TB-500: Provides neuroprotection via caspase-3 inhibition; promotes oligodendrocyte progenitor proliferation through p38 MAPK upregulation [17].
Cellular Migration and Proliferation
- TB-500: G-actin sequestration drives migration; photorelease studies show directional cell turning [7].
- GHK-Cu: Chemoattractant for macrophages, mast cells, and endothelial cells [18].
- BPC-157: Regulates migration via ERK1/2 phosphorylation; transcription factors c-Fos (4.99-fold), c-Jun (7.05-fold), Egr-1 (3.70-fold) upregulated [19].
- KPV: Promotes keratinocyte and fibroblast migration; increased viability in corneal epithelial cultures [20].
Wound Healing Mechanisms
- BPC-157: Accelerates repair phases including inflammation, collagen deposition, angiogenesis, and epithelial recovery [9].
- GHK-Cu: Enhances systemic and local remodeling; collagen dressings improved contraction and antioxidant levels [5].
- TB-500: Promotes organized repair with anti-scarring effects; increased wound contraction (11%) and reepithelialization (42–61%) [10].
- KPV: Accelerates mucosal and corneal healing; complete reepithelialization within 60 hours [14,20].
Oxidative Stress Response
- GHK-Cu: Reduces ROS, increases superoxide dismutase activity, quenches radicals [21].
- TB-500: Upregulates antioxidant enzymes Cu/Zn-SOD and catalase [11].
- BPC-157: Scavenges free radicals, normalizes NO and MDA levels, increases HO-1 and NOS-3 expression [11].
- KPV: Inhibits ROS in keratinocytes via ERK and p38 MAPK modulation [22].
Disclaimer: These peptides are intended strictly for in vitro research applications. They are not for human consumption or therapeutic use.
References
[1] M.-J. Hsieh et al., “Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation,” Springer Science and Business Media LLC, Nov. 2016. doi: 10.1007/s00109-016-1488-y. Available: https://doi.org/10.1007/s00109-016-1488-y
[2] Y. Dou, A. Lee, L. Zhu, J. Morton, and W. Ladiges, “The potential of GHK as an anti-aging peptide,” Ant Publishing, Mar. 2020. doi: 10.31491/apt.2020.03.014. Available: https://doi.org/10.31491/apt.2020.03.014
[3] X. Wang et al., “GHK‐Cu‐liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis,” Wiley, Apr. 2017. doi: 10.1111/wrr.12520. Available: https://doi.org/10.1111/wrr.12520
[4] K. M. Malinda, A. L. Goldstein, and H. K. Kueinman, “Thymosin β 4 stimulates directional migration of human umbilical vein endothelial cells,” Wiley, May 1997. doi: 10.1096/fasebj.11.6.9194528. Available: https://doi.org/10.1096/fasebj.11.6.9194528
[5] L. Pickart and A. Margolina, “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data,” MDPI AG, Jul. 2018. doi: 10.3390/ijms19071987. Available: https://doi.org/10.3390/ijms19071987
[6] C.-H. Chang, W.-C. Tsai, M.-S. Lin, Y.-H. Hsu, and J.-H. S. Pang, “The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration,” American Physiological Society, Mar. 2011. doi: 10.1152/japplphysiol.00945.2010. Available: https://doi.org/10.1152/japplphysiol.00945.2010
[7] B. Xue, C. Leyrat, J. M. Grimes, and R. C. Robinson, “Structural basis of thymosin-β4/profilin exchange leading to actin filament polymerization,” Proceedings of the National Academy of Sciences, Oct. 2014. doi: 10.1073/pnas.1412271111. Available: https://doi.org/10.1073/pnas.1412271111
[8] F.-X. Maquart, L. Pickart, M. Laurent, P. Gillery, J.-C. Monboisse, and J.-P. Borel, “Stimulation of collagen synthesis in fibroblast cultures by the tripeptide‐copper complex glycyl‐L‐histidyl‐L‐lysine‐Cu2+,” Wiley, Oct. 1988. doi: 10.1016/0014-5793(88)80509-x. Available: https://doi.org/10.1016/0014-5793(88)80509-x
[9] S. Seiwerth et al., “Stable Gastric Pentadecapeptide BPC 157 and Wound Healing,” Frontiers Media SA, Jun. 2021. doi: 10.3389/fphar.2021.627533. Available: https://doi.org/10.3389/fphar.2021.627533
[10] K. M. Malinda et al., “Thymosin beta4 accelerates wound healing.,” Journal of Investigative Dermatology, vol. 113 3, pp. 364–8, 1999.
[11] H. Demirtaş, A. Özer, A. K. Yıldırım, A. D. Dursun, Ş. C. Sezen, and M. Arslan, “Protective Effects of BPC 157 on Liver, Kidney, and Lung Distant Organ Damage in Rats with Experimental Lower-Extremity Ischemia–Reperfusion Injury,” MDPI AG, Feb. 2025. doi: 10.3390/medicina61020291. Available: https://doi.org/10.3390/medicina61020291
[12] M. A. Evans et al., “Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing,” Springer Science and Business Media LLC, Jul. 2013. doi: 10.1038/ncomms3081. Available: https://doi.org/10.1038/ncomms3081
[13] G. Dalmasso, L. Charrier–Hisamuddin, H. T. Thu Nguyen, Y. Yan, S. Sitaraman, and D. Merlin, “PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation,” Elsevier BV, Jan. 2008. doi: 10.1053/j.gastro.2007.10.026. Available: https://doi.org/10.1053/j.gastro.2007.10.026
[14] B. Xiao et al., “Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis,” Elsevier BV, Jul. 2017. doi: 10.1016/j.ymthe.2016.11.020. Available: https://doi.org/10.1016/j.ymthe.2016.11.020
[15] L. Pickart, J. M. Vasquez-Soltero, and A. Margolina, “The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging: Implications for Cognitive Health,” Hindawi Limited, 2012. doi: 10.1155/2012/324832. Available: https://doi.org/10.1155/2012/324832
[16] J. Vukojevic et al., “Pentadecapeptide BPC 157 and the central nervous system,” Medknow, 2022. doi: 10.4103/1673-5374.320969. Available: https://doi.org/10.4103/1673-5374.320969
[17] S. Kim, J. Choi, and J. Kwon, “Thymosin Beta 4 Protects Hippocampal Neuronal Cells against PrP (106–126) via Neurotrophic Factor Signaling,” MDPI AG, May 2023. doi: 10.3390/molecules28093920. Available: https://doi.org/10.3390/molecules28093920
[18] L. Pickart, J. M. Vasquez-Soltero, and A. Margolina, “GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration,” Wiley, 2015. doi: 10.1155/2015/648108. Available: https://doi.org/10.1155/2015/648108
[19] T. Huang et al., “Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro,” Informa UK Limited, Apr. 2015. doi: 10.2147/dddt.s82030. Available: https://doi.org/10.2147/dddt.s82030
[20] M. Böhm and T. Luger, “Are melanocortin peptides future therapeutics for cutaneous wound healing?,” Wiley, Feb. 2019. doi: 10.1111/exd.13887. Available: https://doi.org/10.1111/exd.13887
[21] S. Sharma, M. F. Anwar, A. Dinda, M. Singhal, and A. Malik, “In Vitro and in Vivo Studies of pH-Sensitive GHK-Cu-Incorporated Polyaspartic and Polyacrylic Acid Superabsorbent Polymer,” American Chemical Society (ACS), Nov. 2019. doi: 10.1021/acsomega.9b00655. Available: https://doi.org/10.1021/acsomega.9b00655
[22] J. Sung, S.-Y. Ju, S. Park, W.-K. Jung, J.-Y. Je, and S.-J. Lee, “Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK/NF-κB pathway,” Elsevier BV, Aug. 2025. doi: 10.1016/j.tice.2025.102837. Available: https://doi.org/10.1016/j.tice.2025.102837
| Property | GHK-Cu | BPC-157 | TB-500 | KPV |
|---|---|---|---|---|
| Sequence | Gly-His-Lys.Cu.xHAc | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser | Lys-Pro-Val |
| Molecular Formula | C₁₄H₂₃CuN₆O₄ | C₆₂H₉₈N₁₆O₂₂ | C₂₁₂H₃₅₀N₅₆O₇₈S | C₁₇H₃₂N₆O₄ |
| Molecular Weight | 401.91 g/mol | 1419.5 g/mol | 4963.55 g/mol | 384.48 g/mol |
| PubChem CID | 73587 | 9941957 | 16132341 | 125672 |
| CAS Number | 89030-95-5 | 137525-51-0 | 77591-33-4 | 67727-97-3 |
| Synonyms | Copper peptide GHK, Cu-GHK, NSC 661251 | PL-14736, Body-Protection Compound-157, Bepecin | Thymosin-β4 fragment 17-23, TB-500 acetate, Ac-LKKTETQ | α-MSH fragment (11–13), Tripeptide KPV, Ac-KPV-NH2 |
Lyophilized Peptides: Our peptides are supplied in a pure, freeze-dried form with no fillers, ensuring long-term stability and integrity during cold storage. Simply reconstitute with sterile solvent before use, and store aliquots at ≤ –20 °C to protect against repeated freeze–thaw cycles.
For Research Purposes Only
This content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides
