BioAbsorb x 60 Vegetable Capsules X
Regular price
Rs. 22,639
- Unit price
- per
100% Authentic
Made in USA
Authorised distributor
1-5 Days delivery
BioAbsorb x 60 Vegetable Capsules
Regular price
Rs. 22,639
- Unit price
- per
Price includes all duties and taxes
SKU: SUPP-BIOABS
FMI's Choice
BioAbsorb - Integrated Metabolic Research Formula
BioAbsorb is a next-generation metabolic research complex that combines low-dose metformin, highly bioavailable dihydroberberine, and activated B-complex cofactors. This synergistic blend is designed to amplify glucose disposal, improve lipid and vascular health, enhance mitochondrial energy production, and maintain methylation balance.
Mechanistic Claims
- Metformin (125 mg)
- Activates AMPK, improving insulin sensitivity and glucose uptake.
- Enhances GLUT-4 translocation for efficient glucose disposal.
- Provides metabolic benefits in models of insulin resistance.
- DihydroBerberine (125 mg)
- Highly absorbable berberine metabolite with superior bioavailability.
- Improves glycemia and lipid profiles.
- Supports cardiometabolic health via dual AMPK activation.
- Vitamin B₁ (Thiamin, 12.5 mg)
- Cofactor for pyruvate dehydrogenase.
- Restores endothelial function and supports vascular health.
- Vitamin B₂ (Riboflavin, 12.5 mg)
- Precursor to FAD.
- Shown to lower blood pressure in MTHFR-677TT carriers.
- Vitamin B₅ (Pantethine, 12.5 mg)
- Precursor to CoA.
- Reduces LDL-C and non-HDL-C levels.
- Vitamin B₆ (Pyridoxal-5-Phosphate, 17.5 mg)
- Active PLP coenzyme.
- Decreases plasma homocysteine concentrations.
- Vitamin B₉ (Methyl-folate, 200 mcg)
- Active folate form.
- Supports one-carbon metabolism and homocysteine control.
- Vitamin B₁₂ (Methyl-cobalamin, 50 mcg)
-
- Active B₁₂ form.
- Neuroprotective; improves nerve conduction and methylation balance.
Research Areas
- Glucose Disposal & Insulin Sensitivity: Dual AMPK activation via metformin and dihydroberberine.
- Lipid & Cardiovascular Support: Pantethine and riboflavin improve lipid profiles and vascular function.
- Mitochondrial Energy Metabolism: B-complex cofactors enhance ATP production and enzymatic efficiency.
- Methylation & Homocysteine Management: Methyl-folate and methyl-cobalamin maintain one-carbon balance.
- Neuroprotection & Peripheral Nerve Health: Active B₁₂ supports nerve conduction and resilience.
Research Insights
Glucose Disposal & Insulin Sensitivity
Metformin activates hepatic and skeletal-muscle AMPK, suppressing gluconeogenesis and potentiating insulin-stimulated glucose uptake [1] . Dihydroberberine, a reduced berberine metabolite with far superior intestinal absorption, demonstrated greater area-under-the-curve exposure and produced acute reductions in post-prandial glucose in a randomized crossover pilot trial [2] .
Lipid & Endothelial Support
Pantethine (vitamin B₅ derivative) lowered total and LDL cholesterol by 11 % over 16 weeks in a triple-blinded, diet-controlled trial [5] . Low-dose thiamine reversed hyperglycemia-induced endothelial cell dysfunction in vitro, restoring migration capacity and reducing von Willebrand factor secretion [3] . Riboflavin supplementation (1.6 mg day⁻¹) produced clinically meaningful blood-pressure reductions in treated hypertensives carrying the MTHFR 677TT polymorphism [4] .
Methylation & Homocysteine Management
In a randomized controlled trial, combined methyl-folate (5-MTHF), PLP and methyl-cobalamin lowered plasma homocysteine by 30 % and LDL-C by 7.5 % after six months in adults with MTHFR/MTR/MTRR polymorphisms [7] . Independent PLP supplementation has likewise been shown to cut homocysteine while enhancing antioxidant capacity in postsurgical patients [6] .
Neuroprotection & Nerve Health
A 2020 systematic review and meta-analysis of randomized trials found that mecobalamin (methyl-B₁₂) significantly improved nerve-conduction velocity and overall clinical response in peripheral neuropathy, with a favorable safety profile [8] .
References
- Zhou G et al. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest. 2001;108:1167-1174. https://pubmed.ncbi.nlm.nih.gov/11602624/
- Moon JM et al. Absorption kinetics of berberine and dihydroberberine and their impact on glycemia. Nutrients. 2022;14(1):124. https://pubmed.ncbi.nlm.nih.gov/35010998/
- Ascher E et al. Thiamine reverses hyperglycemia-induced dysfunction in cultured endothelial cells. Surgery. 2001;130:851-858. https://pubmed.ncbi.nlm.nih.gov/11685195/
- Wilson CP et al. Blood pressure in hypertensive individuals with the MTHFR 677TT genotype is responsive to riboflavin: targeted randomized trial. Hypertension. 2013;61:1302-1308. https://pubmed.ncbi.nlm.nih.gov/23608654/
- Evans M et al. Pantethine favorably alters LDL and non-HDL cholesterol in low-to-moderate risk subjects. Vasc Health Risk Manag. 2014;10:89-100. https://pubmed.ncbi.nlm.nih.gov/24600231/
- Cheng SB et al. Vitamin B-6 supplementation reduces plasma homocysteine in hepatocellular-carcinoma patients after resection. Biomed Res Int. 2016;2016:7658981. https://pubmed.ncbi.nlm.nih.gov/27051670/
- Pokushalov E et al. Methylfolate, PLP and methylcobalamin supplementation lowers homocysteine and LDL-C: randomized controlled trial. Nutrients. 2024;16:1550. https://pubmed.ncbi.nlm.nih.gov/38892484/
- Sawangjit R et al. Efficacy and safety of mecobalamin on peripheral neuropathy: systematic review and meta-analysis. J Altern Complement Med. 2020;26:1117-1129. https://pubmed.ncbi.nlm.nih.gov/32716261/
Label--
| Supplement Facts Serving Size: 1 Capsule Servings per Container: 60 |
|
| Ingredients | Amount Per Serving |
| Metformin | 125 mg |
| DihydroBerberine | 125 mg |
| Vitamin B₁ (Thiamin) | 12.5 mg |
| Vitamin B₂ (Riboflavin) | 12.5 mg |
| Vitamin B₅ (Pantethine) | 12.5 mg |
| Vitamin B₆ (Pyridoxal-5-Phosphate) | 17.5 mg |
| Vitamin B₉ (Methyl-folate) | 200 mcg |
| Vitamin B₁₂ (Methyl-cobalamin) | 50 mcg |
Dosage--For Research Purposes Only
This content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.
Store in a dry and dark place at room temperature, out of reach of small children.
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100% Authentic
Made in USA
Authorised distributor
3 - 10 days delivery
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Disclaimer
Product Information Sheet
: Not a diet substitute. Seek Medical guidance if unsure before use.
BioAbsorb - Integrated Metabolic Research Formula
BioAbsorb is a next-generation metabolic research complex that combines low-dose metformin, highly bioavailable dihydroberberine, and activated B-complex cofactors. This synergistic blend is designed to amplify glucose disposal, improve lipid and vascular health, enhance mitochondrial energy production, and maintain methylation balance.
Mechanistic Claims
- Metformin (125 mg)
- Activates AMPK, improving insulin sensitivity and glucose uptake.
- Enhances GLUT-4 translocation for efficient glucose disposal.
- Provides metabolic benefits in models of insulin resistance.
- DihydroBerberine (125 mg)
- Highly absorbable berberine metabolite with superior bioavailability.
- Improves glycemia and lipid profiles.
- Supports cardiometabolic health via dual AMPK activation.
- Vitamin B₁ (Thiamin, 12.5 mg)
- Cofactor for pyruvate dehydrogenase.
- Restores endothelial function and supports vascular health.
- Vitamin B₂ (Riboflavin, 12.5 mg)
- Precursor to FAD.
- Shown to lower blood pressure in MTHFR-677TT carriers.
- Vitamin B₅ (Pantethine, 12.5 mg)
- Precursor to CoA.
- Reduces LDL-C and non-HDL-C levels.
- Vitamin B₆ (Pyridoxal-5-Phosphate, 17.5 mg)
- Active PLP coenzyme.
- Decreases plasma homocysteine concentrations.
- Vitamin B₉ (Methyl-folate, 200 mcg)
- Active folate form.
- Supports one-carbon metabolism and homocysteine control.
- Vitamin B₁₂ (Methyl-cobalamin, 50 mcg)
-
- Active B₁₂ form.
- Neuroprotective; improves nerve conduction and methylation balance.
Research Areas
- Glucose Disposal & Insulin Sensitivity: Dual AMPK activation via metformin and dihydroberberine.
- Lipid & Cardiovascular Support: Pantethine and riboflavin improve lipid profiles and vascular function.
- Mitochondrial Energy Metabolism: B-complex cofactors enhance ATP production and enzymatic efficiency.
- Methylation & Homocysteine Management: Methyl-folate and methyl-cobalamin maintain one-carbon balance.
- Neuroprotection & Peripheral Nerve Health: Active B₁₂ supports nerve conduction and resilience.
Research Insights
Glucose Disposal & Insulin Sensitivity
Metformin activates hepatic and skeletal-muscle AMPK, suppressing gluconeogenesis and potentiating insulin-stimulated glucose uptake [1] . Dihydroberberine, a reduced berberine metabolite with far superior intestinal absorption, demonstrated greater area-under-the-curve exposure and produced acute reductions in post-prandial glucose in a randomized crossover pilot trial [2] .
Lipid & Endothelial Support
Pantethine (vitamin B₅ derivative) lowered total and LDL cholesterol by 11 % over 16 weeks in a triple-blinded, diet-controlled trial [5] . Low-dose thiamine reversed hyperglycemia-induced endothelial cell dysfunction in vitro, restoring migration capacity and reducing von Willebrand factor secretion [3] . Riboflavin supplementation (1.6 mg day⁻¹) produced clinically meaningful blood-pressure reductions in treated hypertensives carrying the MTHFR 677TT polymorphism [4] .
Methylation & Homocysteine Management
In a randomized controlled trial, combined methyl-folate (5-MTHF), PLP and methyl-cobalamin lowered plasma homocysteine by 30 % and LDL-C by 7.5 % after six months in adults with MTHFR/MTR/MTRR polymorphisms [7] . Independent PLP supplementation has likewise been shown to cut homocysteine while enhancing antioxidant capacity in postsurgical patients [6] .
Neuroprotection & Nerve Health
A 2020 systematic review and meta-analysis of randomized trials found that mecobalamin (methyl-B₁₂) significantly improved nerve-conduction velocity and overall clinical response in peripheral neuropathy, with a favorable safety profile [8] .
References
- Zhou G et al. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest. 2001;108:1167-1174. https://pubmed.ncbi.nlm.nih.gov/11602624/
- Moon JM et al. Absorption kinetics of berberine and dihydroberberine and their impact on glycemia. Nutrients. 2022;14(1):124. https://pubmed.ncbi.nlm.nih.gov/35010998/
- Ascher E et al. Thiamine reverses hyperglycemia-induced dysfunction in cultured endothelial cells. Surgery. 2001;130:851-858. https://pubmed.ncbi.nlm.nih.gov/11685195/
- Wilson CP et al. Blood pressure in hypertensive individuals with the MTHFR 677TT genotype is responsive to riboflavin: targeted randomized trial. Hypertension. 2013;61:1302-1308. https://pubmed.ncbi.nlm.nih.gov/23608654/
- Evans M et al. Pantethine favorably alters LDL and non-HDL cholesterol in low-to-moderate risk subjects. Vasc Health Risk Manag. 2014;10:89-100. https://pubmed.ncbi.nlm.nih.gov/24600231/
- Cheng SB et al. Vitamin B-6 supplementation reduces plasma homocysteine in hepatocellular-carcinoma patients after resection. Biomed Res Int. 2016;2016:7658981. https://pubmed.ncbi.nlm.nih.gov/27051670/
- Pokushalov E et al. Methylfolate, PLP and methylcobalamin supplementation lowers homocysteine and LDL-C: randomized controlled trial. Nutrients. 2024;16:1550. https://pubmed.ncbi.nlm.nih.gov/38892484/
- Sawangjit R et al. Efficacy and safety of mecobalamin on peripheral neuropathy: systematic review and meta-analysis. J Altern Complement Med. 2020;26:1117-1129. https://pubmed.ncbi.nlm.nih.gov/32716261/
| Supplement Facts Serving Size: 1 Capsule Servings per Container: 60 |
|
| Ingredients | Amount Per Serving |
| Metformin | 125 mg |
| DihydroBerberine | 125 mg |
| Vitamin B₁ (Thiamin) | 12.5 mg |
| Vitamin B₂ (Riboflavin) | 12.5 mg |
| Vitamin B₅ (Pantethine) | 12.5 mg |
| Vitamin B₆ (Pyridoxal-5-Phosphate) | 17.5 mg |
| Vitamin B₉ (Methyl-folate) | 200 mcg |
| Vitamin B₁₂ (Methyl-cobalamin) | 50 mcg |
For Research Purposes Only
This content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.
Store in a dry and dark place at room temperature, out of reach of small children.
