{"title":"Peptides","description":"","products":[{"product_id":"regeno-blend-bpc-157-tb-500-cartalax-30mg-biolongevity-labs","title":"Regeno Blend (BPC-157, TB-500, Cartalax)X30mg","description":"\u003cp\u003eDescription--\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Overview\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis triple-blend peptide brings together three distinct molecular pathways studied in connective tissue research and cellular repair models.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eBPC-157 Research Profile\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eBPC-157 is a stable gastric pentadecapeptide derived from human gastric juice proteins. Laboratory studies demonstrate its activity across vascular endothelial growth factor pathways and nitric oxide-dependent mechanisms[1][2].\u003c\/p\u003e\n\u003cp\u003eThe peptide shows particular activity in musculoskeletal tissue models, where it modulates growth hormone receptor expression in fibroblast cultures. Research documents its influence on ERK1\/2 signaling cascades that regulate cell proliferation and migration[3][4].\u003c\/p\u003e\n\u003cp\u003eStudies on wound healing models reveal rapid gene expression changes and angiogenic activity in laboratory settings[1][5]. The peptide demonstrates cytoprotective properties across diverse cell types in vitro[6].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eTB-500 Research Profile\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTB-500 is a 43-amino acid polypeptide that functions as the primary G-actin sequestering molecule in eukaryotic cells. Its molecular activity extends to actin cytoskeleton regulation and spatial control of polymerization at sites of cell movement[7][8].\u003c\/p\u003e\n\u003cp\u003eLaboratory models show TB-500 activates HIF-1α pathways under hypoxic conditions. The peptide influences cell migration patterns through controlled actin availability at leading cell edges[9][10].\u003c\/p\u003e\n\u003cp\u003eResearch demonstrates angiogenic signaling in vascular cell cultures. Studies document progenitor cell differentiation and anti-apoptotic activity in multiple tissue models[11][12][13].\u003c\/p\u003e\n\u003cp\u003eThe peptide shows measurable effects in dermal fibroblast migration assays and collagen deposition models[14][15].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eCartalax Research Profile\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCartalax is a tripeptide (Ala-Glu-Asp) belonging to the Khavinson bioregulator family. These short peptides demonstrate direct DNA interaction and nuclear penetration in cell culture models[16].\u003c\/p\u003e\n\u003cp\u003eResearch documents epigenetic modulation mechanisms through DNA methylation status changes. The peptide influences gene expression patterns without altering underlying genetic sequences[17][18].\u003c\/p\u003e\n\u003cp\u003eLaboratory studies show tissue-specific activity based on amino acid composition. Cell culture research reveals histone protein interactions that modify chromatin accessibility[19][20].\u003c\/p\u003e\n\u003cp\u003eThe peptide demonstrates proliferation marker changes in aging cell models. Research documents senescence-associated gene modulation in fibroblast cultures[16].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eComplementary Research Applications\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eThe three peptides operate through distinct molecular pathways in laboratory settings. BPC-157 targets vascular and growth factor systems. TB-500 regulates cytoskeletal dynamics and cell motility. Cartalax modulates gene expression at the chromatin level.\u003c\/p\u003e\n\u003cp\u003eThis blend provides researchers with multiple mechanistic entry points for studying connective tissue biology, cellular repair processes, and fibroblast activity in controlled in vitro applications.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eS. Seiwerth \u003cem\u003eet al.\u003c\/em\u003e, “Stable Gastric Pentadecapeptide BPC 157 and Wound Healing,” Frontiers Media SA, Jun. 2021. doi: 10.3389\/fphar.2021.627533.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3389\/fphar.2021.627533\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3389\/fphar.2021.627533\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eF. Amic \u003cem\u003eet al.\u003c\/em\u003e, “Bypassing major venous occlusion and duodenal lesions in rats, and therapy with the stable gastric pentadecapeptide BPC 157, L-NAME and L-arginine,” Baishideng Publishing Group Inc., Dec. 2018. doi: 10.3748\/wjg.v24.i47.5366.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3748\/wjg.v24.i47.5366\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3748\/wjg.v24.i47.5366\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eC.-H. Chang, W.-C. Tsai, Y.-H. Hsu, and J.-H. Pang, “Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts,” MDPI AG, Nov. 2014. doi: 10.3390\/molecules191119066.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3390\/molecules191119066\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/molecules191119066\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eT. Huang \u003cem\u003eet al.\u003c\/em\u003e, “Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro,” Informa UK Limited, Apr. 2015. doi: 10.2147\/dddt.s82030.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.2147\/dddt.s82030\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.2147\/dddt.s82030\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eP. Sikiric \u003cem\u003eet al.\u003c\/em\u003e, “Stable Gastric Pentadecapeptide BPC 157, Robert’s Stomach Cytoprotection\/Adaptive Cytoprotection\/Organoprotection, and Selye’s Stress Coping Response: Progress, Achievements, and the Future,” The Editorial Office of Gut and Liver, Mar. 2020. doi: 10.5009\/gnl18490.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.5009\/gnl18490\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.5009\/gnl18490\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eM. Józwiak, M. Bauer, W. Kamysz, and P. Kleczkowska, “Multifunctionality and Possible Medical Application of the BPC 157 Peptide—Literature and Patent Review,” MDPI AG, Jan. 2025. doi: 10.3390\/ph18020185.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3390\/ph18020185\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/ph18020185\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eY. Xiong \u003cem\u003eet al.\u003c\/em\u003e, “Neuroprotective and neurorestorative effects of thymosin β4 treatment following experimental traumatic brain injury,” Wiley, Oct. 2012. doi: 10.1111\/j.1749-6632.2012.06683.x.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1111\/j.1749-6632.2012.06683.x\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1111\/j.1749-6632.2012.06683.x\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eI. Scheller \u003cem\u003eet al.\u003c\/em\u003e, “Thymosin β4 is essential for thrombus formation by controlling the G-actin\/F-actin equilibrium in platelets,” Ferrata Storti Foundation (Haematologica), Aug. 2021. doi: 10.3324\/haematol.2021.278537.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3324\/haematol.2021.278537\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3324\/haematol.2021.278537\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eS. Tang \u003cem\u003eet al.\u003c\/em\u003e, “TMSB4 Overexpression Enhances the Potency of Marrow Mesenchymal Stromal Cells for Myocardial Repair,” Frontiers Media SA, Jun. 2021. doi: 10.3389\/fcell.2021.670913.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3389\/fcell.2021.670913\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3389\/fcell.2021.670913\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eY. Fan, Y. Gong, P. K. Ghosh, L. M. Graham, and P. L. Fox, “Spatial Coordination of Actin Polymerization and ILK–Akt2 Activity during Endothelial Cell Migration,” Elsevier BV, May 2009. doi: 10.1016\/j.devcel.2009.03.009.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.devcel.2009.03.009\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/j.devcel.2009.03.009\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eD. C. Morris, M. Chopp, L. Zhang, and Z. G. Zhang, “Thymosin β4: a candidate for treatment of stroke?,” Wiley, May 2010. doi: 10.1111\/j.1749-6632.2010.05469.x.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1111\/j.1749-6632.2010.05469.x\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1111\/j.1749-6632.2010.05469.x\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eY. Wang \u003cem\u003eet al.\u003c\/em\u003e, “Thymosin β4 released from functionalized self-assembling peptide activates epicardium and enhances repair of infarcted myocardium,” Ivyspring International Publisher, 2021. doi: 10.7150\/thno.52309.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.7150\/thno.52309\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.7150\/thno.52309\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eH. Peng \u003cem\u003eet al.\u003c\/em\u003e, “Thymosin-β4prevents cardiac rupture and improves cardiac function in mice with myocardial infarction,” American Physiological Society, Sep. 2014. doi: 10.1152\/ajpheart.00129.2014.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1152\/ajpheart.00129.2014\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1152\/ajpheart.00129.2014\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eJ. Jing \u003cem\u003eet al.\u003c\/em\u003e, “Cloning, Expression and Effects of P. americana Thymosin on Wound Healing,” MDPI AG, Oct. 2019. doi: 10.3390\/ijms20194932.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3390\/ijms20194932\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/ijms20194932\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eG. Sosne and E. A. Berger, “Thymosin beta 4: A potential novel adjunct treatment for bacterial keratitis,” Elsevier BV, May 2023. doi: 10.1016\/j.intimp.2023.109953. https:\/\/doi.org\/10.1016\/j.intimp.2023.109953\u003c\/li\u003e\n\u003cli\u003eV. K. Khavinson, I. G. Popovich, N. S. Linkova, E. S. Mironova, and A. R. Ilina, “Peptide Regulation of Gene Expression: A Systematic Review,” MDPI AG, Nov. 2021. doi: 10.3390\/molecules26227053.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3390\/molecules26227053\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/molecules26227053\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eV. Kh. Khavinson, N. S. Lin’kova, and S. I. Tarnovskaya, “Short Peptides Regulate Gene Expression,” Springer Science and Business Media LLC, Dec. 2016. doi: 10.1007\/s10517-016-3596-7.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1007\/s10517-016-3596-7\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1007\/s10517-016-3596-7\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eL. I. Fedoreyeva, I. I. Kireev, V. Kh. Khavinson, and B. F. Vanyushin, “Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA,” Pleiades Publishing Ltd, Nov. 2011. doi: 10.1134\/s0006297911110022.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1134\/s0006297911110022\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1134\/s0006297911110022\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eA. V. Arutjunyan, I. G. Popovich, L. S. Kozina, and G. A. Ryzhak, “Peptide Regulation of Ageing: From Experiment to Practice,” Bentham Science Publishers Ltd., Feb. 2025. doi: 10.2174\/0118746098346230250116065407.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.2174\/0118746098346230250116065407\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.2174\/0118746098346230250116065407\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eL. I. Fedoreyeva, T. A. Smirnova, G. Ya. Kolomijtseva, V. Kh. Khavinson, and B. F. Vanyushin, “Interaction of short peptides with FITC-labeled wheat histones and their complexes with deoxyribooligonucleotides,” Pleiades Publishing Ltd, Feb. 2013. doi: 10.1134\/s0006297913020053.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1134\/s0006297913020053\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1134\/s0006297913020053\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003e\u003cbr\u003eLabel--\u003cstrong\u003eProduct Specifications\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cstrong\u003eSpecification\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eBPC-157\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eTB-500 (Thymosin Beta-4)\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eCartalax (AED)\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSequence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eGly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val\u003c\/td\u003e\n\u003ctd\u003eAc-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser\u003c\/td\u003e\n\u003ctd\u003eAla-Glu-Asp\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC\u003csub\u003e62\u003c\/sub\u003eH\u003csub\u003e98\u003c\/sub\u003eN\u003csub\u003e16\u003c\/sub\u003eO\u003csub\u003e22\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003ctd\u003eC\u003csub\u003e212\u003c\/sub\u003eH\u003csub\u003e350\u003c\/sub\u003eN\u003csub\u003e56\u003c\/sub\u003eO\u003csub\u003e78\u003c\/sub\u003eS\u003c\/td\u003e\n\u003ctd\u003eC\u003csub\u003e12\u003c\/sub\u003eH\u003csub\u003e19\u003c\/sub\u003eN\u003csub\u003e3\u003c\/sub\u003eO\u003csub\u003e8\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1419.5 g\/mol\u003c\/td\u003e\n\u003ctd\u003e4963.4 g\/mol\u003c\/td\u003e\n\u003ctd\u003e333.29 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e137525-51-0\u003c\/td\u003e\n\u003ctd\u003e77591-33-4\u003c\/td\u003e\n\u003ctd\u003e205640-90-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePubChem CID\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e9941957\u003c\/td\u003e\n\u003ctd\u003e16132341\u003c\/td\u003e\n\u003ctd\u003e87815447\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBepecin, Bpc 15, Body protection compound 15, Pentadecapeptide\u003c\/td\u003e\n\u003ctd\u003eThymosin Beta 4, Thymosin β4, TB500, Timbetasin\u003c\/td\u003e\n\u003ctd\u003eT-31, AED, Alanyl-glutamyl-aspartic acid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947410374811,"sku":"BPC-TB5-CARTA-30MG","price":31191.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/BPC-TB5-CARTA-30MG-regeno-blend-bpc-157-tb-500-cartalax-30mg-RET.jpg?v=1770933379"},{"product_id":"5-amino-1mq-10mg-biolongevity-labs","title":"5-Amino-1MQ X 10mg","description":"\u003cp\u003eDescription--5‑Amino‑1MQ is a synthetic nicotinamide N‑methyltransferase (NNMT) inhibitor of interest for in vitro metabolic disease research. By blocking NNMT activity, it modulates intracellular NAD+ and SAM levels, influencing energy production, fat metabolism, and epigenetic regulation. This methylquinolinium derivative is studied as a research compound for understanding metabolic processes, mitochondrial function, and cellular longevity mechanisms.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNNMT Inhibition:\u003c\/strong\u003e Blocks nicotinamide N‑methyltransferase, preventing NAD+ depletion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+ \u0026amp; SAM Modulation:\u003c\/strong\u003e Alters cellular cofactor pools, impacting energy metabolism.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic Regulation:\u003c\/strong\u003e Influences fat metabolism and weight‑related processes in preclinical models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMuscle Preservation:\u003c\/strong\u003e Studied for effects on muscle tissue resilience under metabolic stress.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMitochondrial Function:\u003c\/strong\u003e Explored for roles in supporting mitochondrial efficiency.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCellular Aging:\u003c\/strong\u003e Investigated for potential links to longevity and epigenetic regulation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMetabolic disease and obesity research\u003c\/li\u003e\n\u003cli\u003eNAD+ biology and cofactor regulation studies\u003c\/li\u003e\n\u003cli\u003eMuscle tissue preservation models\u003c\/li\u003e\n\u003cli\u003eMitochondrial function and energy metabolism investigations\u003c\/li\u003e\n\u003cli\u003eCellular aging and epigenetic modulation research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e5‑Amino‑1MQ Research Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSynthetic methylquinolinium derivative with NNMT inhibitory activity.\u003c\/li\u003e\n\u003cli\u003ePreclinical studies highlight roles in weight regulation, muscle preservation, and mitochondrial support.\u003c\/li\u003e\n\u003cli\u003eProvides a research tool for exploring NAD+ metabolism, fat regulation, and cellular aging pathways.\u003c\/li\u003e\n\u003cli\u003eSupplied in lyophilized, filler‑free form to preserve purity and stability.\u003c\/li\u003e\n\u003cli\u003eFor research use only; not intended for therapeutic application.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003e\u003cbr\u003eLabel--\u003cstrong\u003ePeptide Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"bg-bg-100 min-w-full border-separate border-spacing-0 text-sm leading-[1.88888] whitespace-normal\" style=\"width: 99.9363%;\"\u003e\n\u003cthead class=\"border-b-border-100\/50 border-b-[0.5px] text-left\"\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 37.2694%;\"\u003eProperty\u003c\/th\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 62.2175%;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 37.2694%;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 62.2175%;\"\u003eC10H11N2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 37.2694%;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 62.2175%;\"\u003e159.21 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 37.2694%;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 62.2175%;\"\u003e950107\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 37.2694%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 62.2175%;\"\u003e5-amino-1-methylquinolinium, SCHEMBL6403148, CHEMBL4116828, ZMJBCEIHNOWCMC-UHFFFAOYSA-O, STL196667\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp class=\"product_title entry-title elementor-heading-title elementor-size-default\"\u003e \u003c\/p\u003e\n\u003cp class=\"product_title entry-title elementor-heading-title elementor-size-default\"\u003e\u003cstrong\u003e5-Amino-1MQ Peptide Structure\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg data-opt-id=\"1529272240\" decoding=\"async\" src=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/image\/imgsrv.fcgi?cid=950107\u0026amp;t=l\" alt=\"5-Amino-1-methylquinolinium.png\" title=\"5-Amino-1MQ (10mg) 3\"\u003e\u003c\/p\u003e\n\u003cp\u003eSource:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/950107#section=2D-Structure\" rel=\"noopener\" target=\"_blank\"\u003ePubChem\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947411751067,"sku":"5A1MQ-10MG","price":9282.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/5A1MQ-10MG-5-amino-1mq-10mg-RET.jpg?v=1770933379"},{"product_id":"ovagen-peptide-20mg-biolongevity-labs","title":"Ovagen Peptide X 20mg","description":"\u003cp\u003eDescription-- Ovagen is a research‑grade tripeptide bioregulator developed within the Khavinson peptide program. It demonstrates specific affinity for hepatic tissue and is designed for in vitro applications investigating liver and gastrointestinal tract function. Supplied as a high‑purity lyophilized peptide complex, Ovagen provides laboratories with consistent, reliable material for cellular and tissue research.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver Function Support:\u003c\/strong\u003e Targets hepatic tissue pathways in research models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune \u0026amp; GI Regulation:\u003c\/strong\u003e Explored for roles in gastrointestinal tract and immune system modulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCellular Research Utility:\u003c\/strong\u003e Provides a simplified peptide model for studying bioregulatory mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti‑Aging Potential:\u003c\/strong\u003e Investigated for effects on cellular function and tissue resilience.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThymus \u0026amp; Immune Links:\u003c\/strong\u003e As part of Khavinson’s peptide library, contributes to broader immune regulation studies.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLiver function and hepatocyte biology studies\u003c\/li\u003e\n\u003cli\u003eGastrointestinal tract regulation models\u003c\/li\u003e\n\u003cli\u003eImmune system and peptide bioregulator investigations\u003c\/li\u003e\n\u003cli\u003eCellular aging and tissue resilience research\u003c\/li\u003e\n\u003cli\u003eExploratory anti‑aging and regenerative medicine studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOvagen Research Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSynthetic tripeptide bioregulator with hepatic tissue affinity.\u003c\/li\u003e\n\u003cli\u003eDeveloped for in vitro research only; not intended for therapeutic use.\u003c\/li\u003e\n\u003cli\u003eManufactured in USA facilities under rigorous quality control standards.\u003c\/li\u003e\n\u003cli\u003eEach batch undergoes independent third‑party purity verification for reliable outcomes.\u003c\/li\u003e\n\u003cli\u003eSupplied in lyophilized, filler‑free form to preserve integrity and extend shelf life.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOvagen Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eHIV-1 Protease Inhibition Research\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eThe most substantive research on the Glu-Asp-Leu tripeptide comes from HIV-1 protease inhibition studies where EDL functions as a competitive inhibitor derived from the viral transframe region (TFR). The tripeptide represents one of the smallest and most potent analogues derived from the transframe octapeptide (TFP) Phe-Leu-Arg-Glu-Asp-Leu-Ala-Phe, which naturally occurs at the N-terminus of the HIV-1 transframe region[1].\u003c\/p\u003e\n\u003cp\u003eKinetic analysis demonstrates that Glu-Asp-Leu exhibits competitive inhibition of mature HIV-1 protease with a Ki value of approximately 50 μM. This inhibitory potency is remarkable considering the tripeptide’s simple structure compared to conventional HIV protease inhibitors. The closely related tripeptide Glu-Asp-Phe shows even greater potency with a Ki value of approximately 20 μM[1].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cp\u003eJ. M. Louis, F. Dyda, N. T. Nashed, A. R. Kimmel, and D. R. Davies, “Hydrophilic Peptides Derived from the Transframe Region of Gag-Pol Inhibit the HIV-1 Protease,” American Chemical Society (ACS), Feb. 1998. doi: 10.1021\/bi972059x.\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1021\/bi972059x\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1021\/bi972059x\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003eLabel--\u003cstrong\u003ePeptide Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"bg-bg-100 min-w-full border-separate border-spacing-0 text-sm leading-[1.88888] whitespace-normal\"\u003e\n\u003cthead class=\"border-b-border-100\/50 border-b-[0.5px] text-left\"\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] font-400 px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eProperty\u003c\/th\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] font-400 px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003ePeptide Sequence\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eH-Glu-Asp-Leu-OH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eC₁₅H₂₅N₃O₈\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003e375.37 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003e444128\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947411783835,"sku":"OVA-20MG","price":9814.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/OVA-20MG-ovagen-peptide-20mg-RET.jpg?v=1770933379"},{"product_id":"vilon-peptide-20mg-biolongevity-labs","title":"Vilon Peptide X 20mg","description":"\u003cp\u003eDescription--Vilon is a synthetic dipeptide bioregulator composed of L‑lysine and L‑glutamic acid (Lys‑Glu). Classified as a Khavinson peptide bioregulator, it is designed for research use only and has been studied for its role in immune system regulation and thymus function. As one of the shortest active peptide bioregulators, Vilon provides a unique model for examining cellular aging mechanisms and immune modulation in vitro.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune System Modulation:\u003c\/strong\u003e Influences thymus‑related pathways and lymphocyte responses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCellular Aging Research:\u003c\/strong\u003e Studied for effects on heterochromatin organization and cellular senescence.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti‑Aging Potential:\u003c\/strong\u003e Demonstrates measurable activity in laboratory models of immune regulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTumor Research Applications:\u003c\/strong\u003e Explored for roles in immune response modulation in tumor studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimalist Structure:\u003c\/strong\u003e As a dipeptide, offers a simplified yet potent bioregulatory model.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThymus and immune system investigations\u003c\/li\u003e\n\u003cli\u003eLymphocyte response modulation studies\u003c\/li\u003e\n\u003cli\u003eCellular aging and heterochromatin organization research\u003c\/li\u003e\n\u003cli\u003eTumor biology and immune regulation models\u003c\/li\u003e\n\u003cli\u003eExploratory anti‑aging peptide bioregulator studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVilon Research Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSynthetic dipeptide (Lys‑Glu) developed as part of Khavinson’s peptide bioregulator program.\u003c\/li\u003e\n\u003cli\u003eFunctions as a potent research compound targeting thymus‑related immune pathways.\u003c\/li\u003e\n\u003cli\u003eEvidence highlights roles in immune modulation, cellular aging, and tumor research.\u003c\/li\u003e\n\u003cli\u003eSupplied in research‑grade, lyophilized form (freeze‑dried, filler‑free) to preserve purity and stability.\u003c\/li\u003e\n\u003cli\u003eFor research use only; not intended for human or veterinary therapeutic application.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVilon Bioregulator Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVilon peptide represents one of the shortest bioactive compounds studied in laboratory research, consisting of just two amino acids (Lys-Glu). Scientific investigations reveal this dipeptide demonstrates measurable effects across multiple cellular pathways in controlled research environments.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eGene Expression Regulation\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eLaboratory studies show KE peptide binds directly to double-stranded DNA in cell nuclei, specifically targeting GCGC sequences found in 642 gene promoters[1]. This binding mechanism allows the peptide to regulate multiple genes simultaneously in research cell cultures[2].\u003c\/p\u003e\n\u003cp\u003eResearch demonstrates the peptide interacts with histone proteins, potentially altering chromatin structure in laboratory conditions. These modifications may influence gene accessibility and transcription factor binding in controlled studies[1].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eImmune System Modulation\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn vitro experiments reveal Vilon modulates cytokine production in cultured immune cells. The peptide specifically targets the CHUK gene, which encodes components for NF-κB signaling pathway regulation[1].\u003c\/p\u003e\n\u003cp\u003eLaboratory research shows the compound stimulates T-cell differentiation and promotes CD4 and CD5 molecule expression in thymic cell cultures. Studies demonstrate up to 6-fold reduction in inflammatory cytokine synthesis in stimulated cell preparations[2].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eCellular Aging Research\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eResearch indicates Vilon normalizes telomere length in stimulated lymphocyte cultures across different age groups in laboratory conditions. The peptide increases euchromatin proportion while decreasing heterochromatin in aging cell models[2].\u003c\/p\u003e\n\u003cp\u003eGene expression analysis reveals the compound regulates aging-related genes including IGF1, FOXO1, TERT, and NFκB in mesenchymal stem cell cultures. Laboratory studies show reduced apoptosis markers in aging cell preparations treated with the peptide[2].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eCardiovascular Research Applications\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eStudies demonstrate Vilon influences ACE2 gene expression, which encodes angiotensin-converting enzyme 2 in cardiovascular research models. The peptide also regulates AKT1 and AKT2 genes linked to cellular survival and angiogenesis pathways[1].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eMetabolic and Stress Response Studies\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eResearch shows the peptide affects heat shock protein synthesis and cellular stress response mechanisms in laboratory conditions. The compound influences genes encoding proteins involved in energy production and oxidative stress tolerance[2].\u003c\/p\u003e\n\u003cp\u003eLaboratory investigations reveal Vilon regulates matrix metalloproteinase-9 expression and increases Ki-67 synthesis in cultured fibroblast preparations. These findings suggest potential applications in tissue repair research models[2].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cp\u003eN. Linkova \u003cem\u003eet al.\u003c\/em\u003e, “The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19,” MDPI AG, Aug. 2023. doi: 10.3390\/ijms241713377. Available:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3390\/ijms241713377\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/ijms241713377\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eV. Kh. Khavinson, N. S. Linkova, N. I. Chalisova, and O. M. Ivko, “The Use of Thymalin for Immunocorrection and Molecular Aspects of Biological Activity,” Pleiades Publishing Ltd, Jul. 2021. doi: 10.1134\/s2079086421040046. Available:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1134\/s2079086421040046\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1134\/s2079086421040046\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003e\u003cbr\u003eLabel--\u003cstrong\u003ePeptide Specifications\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"bg-bg-100 min-w-full border-separate border-spacing-0 text-sm leading-[1.88888] whitespace-normal\" style=\"width: 99.9363%;\"\u003e\n\u003cthead class=\"border-b-border-100\/50 border-b-[0.5px] text-left\"\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 29.844%;\"\u003eProperty\u003c\/th\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 69.6429%;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 29.844%;\"\u003ePeptide Sequence\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 69.6429%;\"\u003eL-Lys-L-Glu\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 29.844%;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 69.6429%;\"\u003eC₁₁H₂₁N₃O₅\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 29.844%;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 69.6429%;\"\u003e275.3 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 29.844%;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 69.6429%;\"\u003e45234-02-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 29.844%;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 69.6429%;\"\u003e7010502\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 29.844%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 69.6429%;\"\u003eLysylglutamic acid, N-L-Lysyl-L-glutamic acid, H-Lys-Glu-OH, Lysyl glutamate, KE\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947411980443,"sku":"VILON-20MG","price":9816.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/VILON-20MG-vilon-peptide-20mg-RET.jpg?v=1770933379"},{"product_id":"vip-vasoactive-intestinal-peptide-5mg-biolongevity-labs","title":"VIP - Vasoactive Intestinal Peptide X 5mg","description":"\u003cp\u003eDescription--VIP is a 28‑amino acid regulatory hormone peptide that controls smooth muscle relaxation and secretion processes across multiple biological systems. It plays a central role in cellular signaling, vascular function, and secretory regulation, making it a valuable research tool for investigating therapeutic pathways in controlled laboratory settings.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSmooth Muscle Regulation:\u003c\/strong\u003e Mediates relaxation of vascular, gastrointestinal, and respiratory smooth muscle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecretory Control:\u003c\/strong\u003e Influences secretion in endocrine and exocrine tissues.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCellular Signaling:\u003c\/strong\u003e Acts through G‑protein coupled receptors to regulate cyclic AMP pathways.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVascular Function:\u003c\/strong\u003e Supports vasodilation and blood flow regulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroprotective \u0026amp; Immunomodulatory Potential:\u003c\/strong\u003e Explored for roles in inflammation, immune balance, and neuronal signaling.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eVascular biology and vasodilation studies\u003c\/li\u003e\n\u003cli\u003eSmooth muscle physiology investigations\u003c\/li\u003e\n\u003cli\u003eSecretory pathway and endocrine\/exocrine regulation models\u003c\/li\u003e\n\u003cli\u003eNeuroprotection and immunomodulation research\u003c\/li\u003e\n\u003cli\u003eExploratory therapeutic studies in inflammation and respiratory health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVIP Research Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e28‑amino acid peptide hormone with broad systemic regulatory roles.\u003c\/li\u003e\n\u003cli\u003eStudied for effects on smooth muscle, vascular tone, and secretory activity.\u003c\/li\u003e\n\u003cli\u003eResearch highlights potential in immune modulation, neuroprotection, and inflammation control.\u003c\/li\u003e\n\u003cli\u003eSupplied in pharmaceutical‑grade, lyophilized form to ensure purity and stability.\u003c\/li\u003e\n\u003cli\u003eRecommended handling: reconstitute with bacteriostatic water immediately before use; aliquot single‑use portions; store at ≤ –20 °C to avoid repeated freeze–thaw cycles.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVIP Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVIP research spans multiple biological systems, offering laboratories diverse opportunities to study this 28-amino acid peptide’s regulatory mechanisms.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eCardiovascular Research\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eVIP acts as a potent vasodilator by binding to VPAC receptors and increasing nitric oxide production. Laboratory studies show VIP influences coronary blood flow and heart rate regulation through its presence in cardiac nerve fibers[1].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eDigestive System Studies\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eResearch demonstrates VIP’s role in gut motility regulation through smooth muscle relaxation in the esophageal sphincter and stomach. The peptide stimulates pancreatic secretion of water and electrolytes while inhibiting gastric acid production[2].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eImmune System Investigations\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVIP exhibits anti-inflammatory properties by binding to VPAC1 and VPAC2 receptors on immune cells. Studies show the peptide inhibits T-cell proliferation and suppresses inflammatory cytokine production from macrophages and microglia[3].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eNeurological Research\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLaboratory investigations reveal VIP’s neuroprotective effects on dopaminergic neurons through microglial modulation. The peptide plays a central role in circadian rhythm regulation via VPAC2 receptor activation in the suprachiasmatic nucleus[4].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eReceptor Mechanisms\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVIP research focuses on VPAC1 and VPAC2 receptor interactions that trigger adenylate cyclase activation and cAMP elevation[5]. These signaling cascades activate protein kinase A pathways across different cell types[6].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eR. Henning, “Vasoactive intestinal peptide: cardiovascular effects,” Oxford University Press (OUP), Jan. 2001. doi: 10.1016\/s0008-6363(00)00229-7. \u003ca href=\"https:\/\/doi.org\/10.1016\/s0008-6363(00)00229-7\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/s0008-6363(00)00229-7\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eM. Iwasaki, Y. Akiba, and J. D. Kaunitz, “Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal system,” F1000 Research Ltd, Sep. 2019. doi: 10.12688\/f1000research.18039.1. \u003ca href=\"https:\/\/doi.org\/10.12688\/f1000research.18039.1\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.12688\/f1000research.18039.1\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eC. Martínez \u003cem\u003eet al.\u003c\/em\u003e, “A Clinical Approach for the Use of VIP Axis in Inflammatory and Autoimmune Diseases,” MDPI AG, Dec. 2019. doi: 10.3390\/ijms21010065. https:\/\/doi.org\/10.3390\/ijms21010065\u003c\/li\u003e\n\u003cli\u003eJ. Fahrenkrug, “Transmitter Role of Vasoactive Intestinal Peptide,” Wiley, Jun. 1993. doi: 10.1111\/j.1600-0773.1993.tb01344.x. \u003ca href=\"https:\/\/doi.org\/10.1111\/j.1600-0773.1993.tb01344.x\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1111\/j.1600-0773.1993.tb01344.x\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eI. Langer, “Mechanisms involved in VPAC receptors activation and regulation: lessons from pharmacological and mutagenesis studies,” Frontiers Media SA, 2012. doi: 10.3389\/fendo.2012.00129. \u003ca href=\"https:\/\/doi.org\/10.3389\/fendo.2012.00129\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3389\/fendo.2012.00129\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eI. Kato \u003cem\u003eet al.\u003c\/em\u003e, “Transgenic mice overexpressing human vasoactive intestinal peptide (VIP) gene in pancreatic beta cells. Evidence for improved glucose tolerance and enhanced insulin secretion by VIP and PHM-27 in vivo.,”\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJournal of Biological Chemistry\u003c\/em\u003e, vol. 269 33, pp. 21223–8, 1994.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003e\u003cbr\u003eLabel--\u003cstrong\u003ePeptide Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"bg-bg-100 min-w-full border-separate border-spacing-0 text-sm leading-[1.88888] whitespace-normal\" style=\"width: 99.9363%;\"\u003e\n\u003cthead class=\"border-b-border-100\/50 border-b-[0.5px] text-left\"\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 20.4434%;\"\u003eProperty\u003c\/th\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 79.2367%;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 20.4434%;\"\u003ePeptide Sequence\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 79.2367%;\"\u003eHis-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 20.4434%;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 79.2367%;\"\u003eC147H238N44O42S\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 20.4434%;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 79.2367%;\"\u003e3325.8 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 20.4434%;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 79.2367%;\"\u003e40077-57-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 20.4434%;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 79.2367%;\"\u003e53314964\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 20.4434%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 79.2367%;\"\u003eVIP, Aviptadil, Vasoactive Intestinal Polypeptide, Vasoactive Intestinal Peptide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003cp\u003e\u003cbr\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947412406427,"sku":"VIP-5MG","price":9304.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/VIP-5MG-vip-vasoactive-intestinal-peptide-5mg-RET.jpg?v=1770933379"},{"product_id":"glow-blend-ghk-cu-bpc-157-tb-500-70mg-biolongevity-labs","title":"GLOW Blend (GHK-Cu, BPC-157, TB-500) X 70mg","description":"\u003cp\u003eDescription--The GLOW blend is a research‑grade peptide formulation combining GHK‑Cu, BPC‑157, and TB‑500 into a single vial for laboratory investigation. This synergistic blend is designed to support studies on tissue repair, vascular formation, and cellular signaling in vitro and ex vivo models. Each peptide contributes distinct regenerative mechanisms, offering complementary pathways for wound healing and recovery research.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK‑Cu (50 mg):\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003eUp‑regulates wound healing processes.\u003c\/li\u003e\n\u003cli\u003eStimulates collagen and elastin production.\u003c\/li\u003e\n\u003cli\u003eEnhances angiogenic growth‑factor expression.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC‑157 (10 mg):\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003eExhibits gastro‑protective and soft‑tissue repair properties.\u003c\/li\u003e\n\u003cli\u003eModulates nitric oxide signaling and growth‑factor receptor activity.\u003c\/li\u003e\n\u003cli\u003eBalances cytokine responses to reduce inflammation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB‑500 (10 mg):\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003eSynthetic fragment of Thymosin Beta‑4.\u003c\/li\u003e\n\u003cli\u003ePromotes cell migration and angiogenesis.\u003c\/li\u003e\n\u003cli\u003eFunctions via actin‑sequestering and integrin‑linked pathways.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynergistic Potential:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCopper‑mediated extracellular matrix activation (GHK‑Cu).\u003c\/li\u003e\n\u003cli\u003eCytoprotective signaling and anti‑inflammatory effects (BPC‑157).\u003c\/li\u003e\n\u003cli\u003eActin‑dependent cell motility and vascular formation (TB‑500).\u003c\/li\u003e\n\u003cli\u003eTogether, these mechanisms may enhance collagen deposition, angiogenic indices, and recovery metrics in controlled tissue injury models.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTissue repair and wound healing studies\u003c\/li\u003e\n\u003cli\u003eAngiogenesis and vascular biology investigations\u003c\/li\u003e\n\u003cli\u003eCellular signaling and extracellular matrix activation models\u003c\/li\u003e\n\u003cli\u003eIn vitro and ex vivo recovery assays\u003c\/li\u003e\n\u003cli\u003eExploratory regenerative medicine research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGLOW Blend Research Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCombines three regenerative peptides into a single lyophilized formulation.\u003c\/li\u003e\n\u003cli\u003eDesigned for complementary activity across matrix activation, cytoprotection, and cell motility pathways.\u003c\/li\u003e\n\u003cli\u003eEvidence remains preclinical and exploratory, with promising activity in tissue repair and angiogenesis models.\u003c\/li\u003e\n\u003cli\u003eSupplied in freeze‑dried, filler‑free form to maximize stability and preserve chemical integrity.\u003c\/li\u003e\n\u003cli\u003eRecommended storage: reconstitute with sterile solvent prior to use; store aliquots at ≤ –20 °C to avoid repeated freeze–thaw cycles.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch: GHK-Cu, BPC-157, and TB-500 (Thymosin Beta 4)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLaboratory investigations of the GLOW peptide combination reveal synergistic mechanisms for cellular repair, vascular formation, and inflammatory modulation—valuable tools for in vitro research applications.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eAngiogenesis and Vascular Formation\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eBPC-157 demonstrates a unique mechanism by upregulating VEGFR2 expression without affecting VEGF-A levels. This unusual pathway activates the VEGFR2-Akt-eNOS signaling cascade in vascular endothelial cell cultures[1].\u003c\/p\u003e\n\u003cp\u003eGHK-Cu increased VEGF and bFGF expression by 230% in irradiated human dermal fibroblasts at nanomolar concentration[2]. Liposomal delivery systems showed 33.1% increased HUVEC proliferation rates with enhanced expression of cell cycle proteins[3].\u003c\/p\u003e\n\u003cp\u003eTB-500 acts as a potent endothelial cell chemoattractant, stimulating 4-6-fold increases in HUVEC migration[4]. The peptide’s seven amino acid sequence LKKTET shows activity at approximately 50 nanomolar concentration.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eTissue Repair and Regeneration\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eThe actions of the GHK-Cu peptide include modulating 31.2% of human genes (4,192 genes) with ≥50% expression changes[5]. The peptide binds to integrin-linked kinase on cell membranes, activating ILK-related pathways.\u003c\/p\u003e\n\u003cp\u003eBPC-157 promotes tissue regeneration through FAK-paxillin pathway activation. This mechanism dramatically increases phosphorylation of focal adhesion kinase and paxillin proteins without changing total protein amounts[6].\u003c\/p\u003e\n\u003cp\u003eTB-500’s regenerative effects stem from G-actin sequestration activity—binding monomeric G-actin in a 1:1 ratio. Rat wound healing models demonstrated 42-61% increased reepithelialization with enhanced collagen deposition[7].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eCollagen Synthesis and Extracellular Matrix\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eGHK-Cu stimulates collagen synthesis at picomolar to nanomolar concentrations[8]. The peptide increased decorin production by 302% and stimulated glycosaminoglycan accumulation in skin fibroblasts.\u003c\/p\u003e\n\u003cp\u003eBPC-157 enhances collagen formation across multiple tissue types in animal models. Studies show significantly increased collagen, reticulin, and blood vessel formation[9].\u003c\/p\u003e\n\u003cp\u003eTB-500 demonstrates anti-fibrotic properties while promoting organized collagen deposition. Treated wounds show tightly organized mature collagen fibers with reduced myofibroblast formation[10].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eInflammatory Modulation\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eGHK-Cu works to reduce inflammation by inhibiting NF-κB p65 and p38 MAPK pathways. The peptide decreased ROS levels and reduced production of pro-inflammatory cytokines TNF-α and IL-6 in macrophage cell cultures[2].\u003c\/p\u003e\n\u003cp\u003eBPC-157 decreased TNF-α, IL-6, and IL-1β levels in tissue samples. The peptide reduced COX-2 gene expression and myeloperoxidase activity in various inflammation models[11].\u003c\/p\u003e\n\u003cp\u003eTB-500 exhibits biphasic regulation of the inflammatory response. The peptide downregulates TNF-α (6.2-fold reduction) and IL-6 (4.1-fold reduction) while upregulating anti-inflammatory IL-10 (8.1-fold increase)[12].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eNeuroprotection and Neural Mechanisms\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eGHK-Cu increases production of nerve growth factor and neurotrophins NT-3 and NT-4[13]. Delivery showed enhanced spatial memory and learning navigation in aging models.\u003c\/p\u003e\n\u003cp\u003eBPC-157 demonstrates complex neurotransmitter system modulation[14]. The peptide interacts with dopaminergic systems without directly binding to dopamine receptors.\u003c\/p\u003e\n\u003cp\u003eTB-500 provides neuroprotection through anti-apoptotic effects via caspase-3 inhibition. The peptide promotes oligodendrocyte progenitor cell proliferation and differentiation through p38 MAPK upregulation[15].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eCellular Migration and Proliferation\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eTB-500’s G-actin sequestration represents the primary mechanism for cellular migration[7]. Local photorelease of caged TB-500 causes directional cell turning in locomoting keratocytes.\u003c\/p\u003e\n\u003cp\u003eGHK-Cu acts as a potent chemoattractant for macrophages, mast cells, and capillary endothelial cells[16]. Irradiated fibroblasts treated with GHK showed growth dynamics similar to non-irradiated control cells.\u003c\/p\u003e\n\u003cp\u003eBPC-157 regulates cellular migration through ERK1\/2 phosphorylation[17]. Downstream transcription factors showed dramatic upregulation: c-Fos by 4.99-fold, c-Jun by 7.05-fold, and Egr-1 by 3.70-fold.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eWound Healing Mechanisms\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eBPC-157 demonstrates route-independent efficacy. The peptide accelerates cellular repair phases including inflammation, collagen deposition, angiogenesis, and epithelial repair[9].\u003c\/p\u003e\n\u003cp\u003eGHK-Cu enhances wound healing through systemic effects and local tissue remodeling. Collagen dressing with incorporated GHK resulted in faster wound contraction and higher glutathione and ascorbic acid levels[5].\u003c\/p\u003e\n\u003cp\u003eTB-500 promotes organized wound repair with anti-scarring properties. The peptide enhanced wound contraction by 11% and increased reepithelialization by 42-61% in full-thickness wound models[10].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eOxidative Stress Response\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eGHK-Cu demonstrates potent ROS reduction in cell cultures[18]. The peptide increased superoxide dismutase activity and quenched hydroxyl and peroxyl radicals.\u003c\/p\u003e\n\u003cp\u003eTB-500 provides targeted upregulation of antioxidant enzymes[11]. Pretreatment reduced intracellular ROS levels and upregulated Cu\/Zn-SOD and catalase.\u003c\/p\u003e\n\u003cp\u003eBPC-157 functions as a free radical scavenger. The peptide normalizes nitric oxide and malondialdehyde levels while increasing expression of antioxidant enzymes heme oxygenase-1 and NOS-3[11].\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eThese peptides are intended for in vitro laboratory research purposes only and are not intended for human consumption or therapeutic use.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eM.-J. Hsieh \u003cem\u003eet al.\u003c\/em\u003e, “Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation,” Springer Science and Business Media LLC, Nov. 2016. doi: 10.1007\/s00109-016-1488-y. Available:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1007\/s00109-016-1488-y\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1007\/s00109-016-1488-y\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eY. Dou, A. Lee, L. Zhu, J. Morton, and W. Ladiges, “The potential of GHK as an anti-aging peptide,” Ant Publishing, Mar. 2020. doi: 10.31491\/apt.2020.03.014. Available: \u003ca href=\"https:\/\/doi.org\/10.31491\/apt.2020.03.014\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.31491\/apt.2020.03.014\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eX. Wang \u003cem\u003eet al.\u003c\/em\u003e, “GHK‐Cu‐liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis,” Wiley, Apr. 2017. doi: 10.1111\/wrr.12520. Available:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1111\/wrr.12520\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1111\/wrr.12520\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eK. M. Malinda, A. L. Goldstein, and H. K. Kueinman, “Thymosin β            4            stimulates directional migration of human umbilical vein endothelial cells,” Wiley, May 1997. doi: 10.1096\/fasebj.11.6.9194528. Available:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1096\/fasebj.11.6.9194528\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1096\/fasebj.11.6.9194528\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eL. Pickart and A. Margolina, “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data,” MDPI AG, Jul. 2018. doi: 10.3390\/ijms19071987. Available: \u003ca href=\"https:\/\/doi.org\/10.3390\/ijms19071987\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/ijms19071987\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eC.-H. Chang, W.-C. Tsai, M.-S. Lin, Y.-H. Hsu, and J.-H. S. Pang, “The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration,” American Physiological Society, Mar. 2011. doi: 10.1152\/japplphysiol.00945.2010. Available: \u003ca href=\"https:\/\/doi.org\/10.1152\/japplphysiol.00945.2010\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1152\/japplphysiol.00945.2010\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eB. Xue, C. Leyrat, J. M. Grimes, and R. C. Robinson, “Structural basis of thymosin-β4\/profilin exchange leading to actin filament polymerization,” Proceedings of the National Academy of Sciences, Oct. 2014. doi: 10.1073\/pnas.1412271111. Available: \u003ca href=\"https:\/\/doi.org\/10.1073\/pnas.1412271111\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1073\/pnas.1412271111\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eF.-X. Maquart, L. Pickart, M. Laurent, P. Gillery, J.-C. Monboisse, and J.-P. Borel, “Stimulation of collagen synthesis in fibroblast cultures by the tripeptide‐copper complex glycyl‐L‐histidyl‐L‐lysine‐Cu2+,” Wiley, Oct. 1988. doi: 10.1016\/0014-5793(88)80509-x. Available: \u003ca href=\"https:\/\/doi.org\/10.1016\/0014-5793(88)80509-x\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/0014-5793(88)80509-x\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eS. Seiwerth \u003cem\u003eet al.\u003c\/em\u003e, “Stable Gastric Pentadecapeptide BPC 157 and Wound Healing,” Frontiers Media SA, Jun. 2021. doi: 10.3389\/fphar.2021.627533. Available:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3389\/fphar.2021.627533\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3389\/fphar.2021.627533\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eK. M. Malinda \u003cem\u003eet al.\u003c\/em\u003e, “Thymosin beta4 accelerates wound healing.,”\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJournal of Investigative Dermatology\u003c\/em\u003e, vol. 113 3, pp. 364–8, 1999.\u003c\/li\u003e\n\u003cli\u003eH. Demirtaş, A. Özer, A. K. Yıldırım, A. D. Dursun, Ş. C. Sezen, and M. Arslan, “Protective Effects of BPC 157 on Liver, Kidney, and Lung Distant Organ Damage in Rats with Experimental Lower-Extremity Ischemia–Reperfusion Injury,” MDPI AG, Feb. 2025. doi: 10.3390\/medicina61020291. Available: \u003ca href=\"https:\/\/doi.org\/10.3390\/medicina61020291\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/medicina61020291\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eM. A. Evans \u003cem\u003eet al.\u003c\/em\u003e, “Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing,” Springer Science and Business Media LLC, Jul. 2013. doi: 10.1038\/ncomms3081. Available:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1038\/ncomms3081\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1038\/ncomms3081\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eL. Pickart, J. M. Vasquez-Soltero, and A. Margolina, “The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging: Implications for Cognitive Health,” Hindawi Limited, 2012. doi: 10.1155\/2012\/324832. Available: \u003ca href=\"https:\/\/doi.org\/10.1155\/2012\/324832\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1155\/2012\/324832\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eJ. Vukojevic \u003cem\u003eet al.\u003c\/em\u003e, “Pentadecapeptide BPC 157 and the central nervous system,” Medknow, 2022. doi: 10.4103\/1673-5374.320969. Available:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.4103\/1673-5374.320969\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.4103\/1673-5374.320969\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eS. Kim, J. Choi, and J. Kwon, “Thymosin Beta 4 Protects Hippocampal Neuronal Cells against PrP (106–126) via Neurotrophic Factor Signaling,” MDPI AG, May 2023. doi: 10.3390\/molecules28093920. Available:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3390\/molecules28093920\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/molecules28093920\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eL. Pickart, J. M. Vasquez-Soltero, and A. Margolina, “GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration,” Wiley, 2015. doi: 10.1155\/2015\/648108. Available:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1155\/2015\/648108\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1155\/2015\/648108\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eT. Huang \u003cem\u003eet al.\u003c\/em\u003e, “Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro,” Informa UK Limited, Apr. 2015. doi: 10.2147\/dddt.s82030. Available:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.2147\/dddt.s82030\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.2147\/dddt.s82030\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eS. Sharma, M. F. Anwar, A. Dinda, M. Singhal, and A. Malik, “In Vitro and in Vivo Studies of pH-Sensitive GHK-Cu-Incorporated Polyaspartic and Polyacrylic Acid Superabsorbent Polymer,” American Chemical Society (ACS), Nov. 2019. doi: 10.1021\/acsomega.9b00655. Available: \u003ca href=\"https:\/\/doi.org\/10.1021\/acsomega.9b00655\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1021\/acsomega.9b00655\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003eLabel--\u003cstrong\u003ePeptide Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cstrong\u003eProperty\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eGHK-Cu\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eBPC-157\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eTB-500\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSequence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e Gly-His-Lys.Cu.xHAc\u003c\/td\u003e\n\u003ctd\u003eGly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val\u003c\/td\u003e\n\u003ctd\u003eAc-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC₁₄H₂₃CuN₆O₄\u003c\/td\u003e\n\u003ctd\u003eC₆₂H₉₈N₁₆O₂₂\u003c\/td\u003e\n\u003ctd\u003eC₂₁₂H₃₅₀N₅₆O₇₈S\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e401.91 g\/mol\u003c\/td\u003e\n\u003ctd\u003e1419.5 g\/mol\u003c\/td\u003e\n\u003ctd\u003e4963.55 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePubChem CID\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e73587\u003c\/td\u003e\n\u003ctd\u003e9941957\u003c\/td\u003e\n\u003ctd\u003e16132341\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e89030-95-5\u003c\/td\u003e\n\u003ctd\u003e137525-51-0\u003c\/td\u003e\n\u003ctd\u003e77591-33-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCopper peptide GHK, Cu-GHK, NSC 661251\u003c\/td\u003e\n\u003ctd\u003ePL-14736, Body-Protection Compound-157, Bepecin\u003c\/td\u003e\n\u003ctd\u003eThymosin-β4 fragment 17-23, TB-500 acetate, Ac-LKKTETQ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947414208667,"sku":"BPC-TB5-GHK-70MG","price":30658.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/BPC-TB5-GHK-70MG-glow-blend-ghk-cu-bpc-157-tb-500-70mg-RET.jpg?v=1770933379"},{"product_id":"kpv-10mg-biolongevity-labs","title":"KPV X 10mg","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003eKPV is the C‑terminal tripeptide fragment of α‑melanocyte stimulating hormone (α‑MSH). As a small, bioactive peptide, it reproduces many of α‑MSH’s anti‑inflammatory, antimicrobial, and tissue‑protective activities, while avoiding full‑length melanocortin receptor signaling in certain contexts. Its compact structure makes it a useful research tool for studying innate immune regulation, mucosal defense, and novel anti‑inflammatory mechanisms.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti‑Inflammatory Action:\u003c\/strong\u003e Suppresses pro‑inflammatory cytokines and leukocyte activation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntimicrobial Activity:\u003c\/strong\u003e Exhibits candidacidal and bactericidal effects, reported for α‑MSH C‑terminal fragments including KPV.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMucosal \u0026amp; Epithelial Protection:\u003c\/strong\u003e Accelerates epithelial repair in corneal and other epithelial models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti‑Fibrotic \u0026amp; Immunomodulatory Effects:\u003c\/strong\u003e Reduces fibrosis and shifts macrophage phenotypes in preclinical studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInnate Immune Regulation:\u003c\/strong\u003e Provides a simplified model for studying α‑MSH‑derived peptide activity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInflammation and cytokine modulation studies\u003c\/li\u003e\n\u003cli\u003eAntimicrobial peptide research (fungal and bacterial models)\u003c\/li\u003e\n\u003cli\u003eMucosal defense and epithelial wound healing investigations\u003c\/li\u003e\n\u003cli\u003eFibrosis and macrophage phenotype modulation studies\u003c\/li\u003e\n\u003cli\u003eExploratory therapeutic models in immune regulation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKPV Research Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSmall tripeptide fragment (Lys–Pro–Val) derived from α‑MSH.\u003c\/li\u003e\n\u003cli\u003eRetains many anti‑inflammatory and antimicrobial properties of the parent hormone.\u003c\/li\u003e\n\u003cli\u003eStudied for roles in immune modulation, wound healing, and tissue protection.\u003c\/li\u003e\n\u003cli\u003eEvidence remains largely preclinical, with promising activity in epithelial and immune models.\u003c\/li\u003e\n\u003cli\u003eProvided in lyophilized form (freeze‑dried, filler‑free) to preserve purity and shelf life.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Overview\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eKPV (Lys-Pro-Val) is a C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (alpha-MSH, positions 11-13) that has been studied for its anti-inflammatory properties in laboratory settings. Research demonstrates KPV operates through melanocortin receptor-independent pathways, making it distinct from its parent molecule.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMolecular Mechanisms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eKPV enters cells via the PepT1 oligopeptide transporter with high affinity (Km ~160 μM in Caco2 cells). Studies show the peptide accumulates in the nucleus within 5 hours, where it competitively disrupts the interaction between p65RelA and importin-α3, blocking NFκB nuclear translocation.\u003csup\u003e[1]\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eAt nanomolar concentrations (10 nM), KPV also suppresses all three major MAPK subfamilies (ERK1\/2, JNK, p38) in intestinal epithelial cells. This mechanism occurs independently of melanocortin receptors and reduces inflammatory cytokine expression.\u003csup\u003e[2]\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGastrointestinal Inflammation Models\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eOral KPV administration in murine DSS and TNBS colitis models demonstrated significant reductions in:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eColonic myeloperoxidase activity (~50% decrease, p\u0026lt;0.05)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003ePro-inflammatory cytokine mRNA (IL-6, IL-12, TNF-α, IFN-γ)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eEpithelial damage and inflammatory cell infiltration\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBody weight loss and colon shortening\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eResearch indicates KPV’s efficacy correlates with PepT1 expression, which becomes upregulated in inflamed colonic epithelium and immune cells during IBD (inflammatory bowel disease).\u003csup\u003e[1]\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAirway and Pulmonary Studies\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn bronchial epithelial cells (16HBE14o-), KPV reduced TNFα-induced inflammatory responses:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eNFκB reporter activity decreased at concentrations ≥1 μg\/ml\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eIL-8 mRNA reduced by ~35% (p\u0026lt;0.05)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eMMP-9 gelatinolytic activity returned to baseline levels\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eEotaxin secretion significantly attenuated\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese findings suggest potential applications in respiratory inflammation research models.\u003csup\u003e[2]\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmune Cell Modulation\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHuman Jurkat T cells and intestinal immune populations express functional PepT1, enabling KPV uptake. Studies demonstrate that 10 nM KPV stabilizes IκBα protein levels and reduces IL-8 transcription by ~40% following TNFα stimulation.\u003c\/p\u003e\n\u003cp\u003eDuring inflammatory conditions, PepT1 expression increases in lamina propria macrophages and peripheral T cells, providing disease-activated delivery pathways for peptide-based research tools.\u003csup\u003e[1]\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDermatological Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eKPV retains anti-inflammatory activity without activating MC1R, the melanogenesis receptor. This property makes it useful for skin inflammation research where pigmentation effects would confound results.\u003csup\u003e[3]\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eStereoisomers like KdPT (Lys-D-Pro-Thr) show enhanced proteolytic stability. Research on sebocytes demonstrated KdPT suppresses IL-1β-mediated cytokine signaling, relevant to acne pathogenesis studies.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStructure-Activity Relationships\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe tripeptide KPV represents the minimal α-MSH sequence retaining anti-inflammatory activity. Deletion studies confirm truncation beyond KPV eliminates efficacy.\u003csup\u003e[4]\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eD-amino acid substitutions (KdPV, KPdV, dKPV) preserve activity while enhancing proteolytic resistance. Glycoalkylation of the lysine residue increases stability but eliminates antimicrobial properties, demonstrating structure-dependent bioactivity profiles.\u003csup\u003e[5]\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Use Only:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eKPV is intended for in vitro laboratory research and experimental protocols. All findings referenced represent preclinical research models and are not validated for therapeutic applications.\u003c\/p\u003e\n\u003cp\u003eReferences\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eDalmasso G, Charrier–Hisamuddin L, Thu Nguyen HT, Yan Y, Sitaraman S, Merlin D. PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation. Elsevier BV; 2008.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1053\/j.gastro.2007.10.026\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1053\/j.gastro.2007.10.026\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eLand S. Inhibition of cellular and systemic inflammation cues in human bronchial epithelial cells by melanocortin-related peptides: mechanism of KPV action and a role for MC3R agonists. International Journal of Physiology, Pathophysiology and Pharmacology 2012;4 2:59–73.\u003c\/li\u003e\n\u003cli\u003eBöhm M, Luger T. Are melanocortin peptides future therapeutics for cutaneous wound healing?. Wiley; 2019.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1111\/exd.13887\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1111\/exd.13887\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eLuger TA, Brzoska T. α-MSH related peptides: a new class of anti-inflammatory and immunomodulating drugs. Elsevier BV; 2007.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1136\/ard.2007.079780\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1136\/ard.2007.079780\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSongok AC, Panta P, Doerrler WT, Macnaughtan MA, Taylor CM. Structural modification of the tripeptide KPV by reductive “glycoalkylation” of the lysine residue. Public Library of Science (PLoS); 2018.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1371\/journal.pone.0199686\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1371\/journal.pone.0199686\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003eLabel--\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eProperty\u003c\/th\u003e\n\u003cth\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePeptide Sequence\u003c\/td\u003e\n\u003ctd\u003eLys-Pro-Val (H-Lys-Pro-Val-OH)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd\u003eC16H30N4O4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd\u003e342.43 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS Number\u003c\/td\u003e\n\u003ctd\u003e67727-97-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubChem CID\u003c\/td\u003e\n\u003ctd\u003e125672\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSynonyms\u003c\/td\u003e\n\u003ctd\u003eα-MSH(11-13), ACTH(11-13), MSH(11-13)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947414732955,"sku":"KPV-10MG","price":33348.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/KPV-10MG-kpv-10mg-RET.jpg?v=1770933379"},{"product_id":"nad-mots-c-5-amino-1mq-blend-120mg-100mg-10mg-biolongevity-labs","title":"NAD+ \/ MOTS-c \/ 5-Amino-1MQ Blend – 120mg (100mg \/ 10mg \/ 10mg)","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003eThe BioLongevity Labs NAD+ \/ MOTS‑c \/ 5‑Amino‑1MQ Blend unites three distinct compounds that converge on cellular energy, mitochondrial function, and metabolic regulation. Their complementary mechanisms are designed to enhance energy balance, improve metabolic health, and support cognitive and longevity research.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eNAD+ (100 mg):\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eCentral redox cofactor for glycolysis, β‑oxidation, and oxidative phosphorylation.\u003c\/li\u003e\n\u003cli\u003eSubstrate for sirtuins and PARPs, supporting DNA repair, gene expression, and stress response.\u003c\/li\u003e\n\u003cli\u003eDeclining levels with age linked to metabolic dysfunction and disease susceptibility.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eMOTS‑c (10 mg):\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eMitochondria‑derived peptide that activates AMPK.\u003c\/li\u003e\n\u003cli\u003eRegulates nuclear gene expression under metabolic stress.\u003c\/li\u003e\n\u003cli\u003eEnhances insulin sensitivity and glucose regulation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003e5‑Amino‑1MQ (10 mg):\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eInhibits NNMT (nicotinamide N‑methyltransferase), raising NAD+ levels.\u003c\/li\u003e\n\u003cli\u003eModulates histone methylation and epigenetic regulation.\u003c\/li\u003e\n\u003cli\u003eInfluences fat metabolism and energy balance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eSynergistic Potential:\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli style=\"list-style-type: none;\"\u003e\n\u003cul\u003e\n\u003cli\u003eRestores NAD+ pools while activating AMPK.\u003c\/li\u003e\n\u003cli\u003eReduces adiposity, sustains muscle function, and optimizes glucose metabolism.\u003c\/li\u003e\n\u003cli\u003eSupports neuroprotection and longevity through effects on oxidative stress, neuroinflammation, and cellular senescence.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCellular energy \u0026amp; mitochondrial function studies\u003c\/li\u003e\n\u003cli\u003eMetabolic regulation \u0026amp; obesity research\u003c\/li\u003e\n\u003cli\u003eMuscle preservation \u0026amp; physical performance models\u003c\/li\u003e\n\u003cli\u003eNeuroprotection \u0026amp; cognitive function investigations\u003c\/li\u003e\n\u003cli\u003eLongevity \u0026amp; anti‑aging mechanisms\u003c\/li\u003e\n\u003cli\u003eExploratory preclinical cancer research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBlend Research Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+:\u003c\/strong\u003e Universal coenzyme central to metabolism, DNA repair, and sirtuin activation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMOTS‑c:\u003c\/strong\u003e Mitochondria‑derived peptide with AMPK activation and insulin sensitivity effects.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e5‑Amino‑1MQ:\u003c\/strong\u003e NNMT inhibitor that boosts NAD+ and modulates epigenetic and metabolic pathways.\u003c\/li\u003e\n\u003cli\u003eTogether, these compounds provide a multi‑modal approach to cellular energy, metabolic health, and longevity research.\u003c\/li\u003e\n\u003cli\u003eEvidence remains largely\u003cstrong\u003e \u003c\/strong\u003epreclinical, with growing interest in translational applications for aging, metabolic disorders, and neurodegeneration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBlend Structure\u003c\/b\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 99.9363%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 15.6474%;\"\u003e\u003cb\u003eIngredient\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 16.6706%;\"\u003e\u003cb\u003eDose (per capsule)\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.9757%;\"\u003e\u003cb\u003eKey Actions\u003c\/b\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 15.6474%;\"\u003e\u003cb\u003eNAD+\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 16.6706%;\"\u003e\u003cspan\u003e100 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.9757%;\"\u003e\u003cspan\u003eCofactor in redox metabolism; activates sirtuins \u0026amp; AMPK; supports DNA repair \u0026amp; mitochondrial biogenesis [1][2][3]\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 15.6474%;\"\u003e\u003cb\u003eMOTS-c\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 16.6706%;\"\u003e\u003cspan\u003e10 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.9757%;\"\u003e\u003cspan\u003eMitochondria-encoded peptide; AMPK activation; improves insulin sensitivity; prevents metabolic dysfunction [4][5][6]\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 15.6474%;\"\u003e\u003cb\u003e5-Amino-1MQ\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 16.6706%;\"\u003e\u003cspan\u003e10 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.9757%;\"\u003e\u003cspan\u003eNNMT inhibitor; ↑NAD+; ↓adiposity; epigenetic modulation; metabolic \u0026amp; oncology research [7][8][9]\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNAD+\/MOTS-c\/5-Amino-1MQ Peptide Blend Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eCellular Energy \u0026amp; Mitochondrial Function\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eNAD+ plays a vital role in redox reactions and sirtuin activation. Restoring NAD+ levels in aging and metabolic stress models improved glucose tolerance, mitochondrial function, and overall health [1]. MOTS-c translocates to the nucleus during metabolic stress to regulate antioxidant and glucose metabolism genes via AMPK activation [4]. 5-Amino-1MQ further boosts NAD+ by inhibiting NNMT, enhancing redox balance and mitochondrial efficiency [7].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eMetabolic Regulation \u0026amp; Obesity Research\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eNAD+ depletion contributes to obesity and metabolic disorders; replenishment strategies improve metabolic homeostasis [2]. MOTS-c prevents diet-induced obesity and insulin resistance by improving glucose utilization and maintaining adipose homeostasis [5]. 5-Amino-1MQ reduces white adipose tissue and body weight in preclinical obesity models without affecting appetite, highlighting its direct metabolic actions [8].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eNeuroprotection \u0026amp; Longevity\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eNAD+ enhancement has been shown to reduce neuroinflammation and improve cognition in models of neurodegeneration [3]. MOTS-c enhances memory formation and protects against neuroinflammation, with benefits observed in Alzheimer’s and metabolic dysfunction models [6]. 5-Amino-1MQ alters histone methylation and metabolic programs in cancer and aging models, representing a promising target for longevity and oncology research [9].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eReferences\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNAD+\u003c\/b\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cspan\u003eRajman L, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eCell Metab.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2018. Therapeutic potential of NAD-boosting molecules in vivo.\u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1016\/j.cmet.2018.02.011\" target=\"_blank\"\u003e\u003cspan\u003e https:\/\/doi.org\/10.1016\/j.cmet.2018.02.011\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eOkabe K, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eJ Biomed Sci.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2019. Altered NAD+ metabolism in metabolic disorders. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1186\/s12929-019-0527-8\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/doi.org\/10.1186\/s12929-019-0527-8\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eZhao Y, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eJ Neuroinflammation.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2021. NAD+ improves cognition via Sirt1\/PGC-1α. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1186\/s12974-021-02250-8\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/doi.org\/10.1186\/s12974-021-02250-8\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cb\u003eMOTS-c\u003c\/b\u003e\u003c\/p\u003e\n\u003col start=\"4\"\u003e\n\u003cli\u003e\n\u003cspan\u003eKim K, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eCell Metab.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2018. MOTS-c translocates to the nucleus during metabolic stress. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1016\/j.cmet.2018.06.008\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/doi.org\/10.1016\/j.cmet.2018.06.008\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eLu H, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eJ Mol Med.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2019. MOTS-c regulates adipose homeostasis and prevents metabolic dysfunction.\u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1007\/s00109-018-01738-w\" target=\"_blank\"\u003e\u003cspan\u003e https:\/\/doi.org\/10.1007\/s00109-018-01738-w\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eLee C, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eCell Metab.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2015. MOTS-c promotes metabolic homeostasis and reduces obesity\/insulin resistance. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1016\/j.cmet.2015.02.009\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/doi.org\/10.1016\/j.cmet.2015.02.009\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cb\u003e5-Amino-1MQ\u003c\/b\u003e\u003c\/p\u003e\n\u003col start=\"7\"\u003e\n\u003cli\u003e\n\u003cspan\u003eConlon N, Ford D. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eBiochem Pharmacol.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2022. Systems approach to NAD+ restoration via NNMT inhibition. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1016\/j.bcp.2022.114946\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/doi.org\/10.1016\/j.bcp.2022.114946\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eLiu J, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eBiomed Res Int.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2021. NNMT inhibition reduces obesity and diabetes risk. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1155\/2021\/9924314\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/doi.org\/10.1155\/2021\/9924314\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eLi X, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eFront Oncol.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2022. NNMT as a biomarker and target in cancer. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.3389\/fonc.2022.894744\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/doi.org\/10.3389\/fonc.2022.894744\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003e\u003cbr\u003eLabel--\u003cb\u003ePeptide Structures\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable style=\"width: 101.465%; height: 315.281px;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"height: 78.375px;\"\u003e\n\u003cth style=\"width: 16.5507%; height: 78.375px;\"\u003e\u003cstrong\u003eProperty\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth style=\"width: 28.726%; height: 78.375px;\"\u003e\u003cb\u003eNAD+ (Nicotinamide Adenine Dinucleotide)\u003c\/b\u003e\u003c\/th\u003e\n\u003cth style=\"width: 30.2134%; height: 78.375px;\"\u003e\u003cb\u003eMOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)\u003c\/b\u003e\u003c\/th\u003e\n\u003cth style=\"width: 23.4338%; height: 78.375px;\"\u003e\u003cb\u003e5-Amino-1MQ (5-Amino-1-methylquinolinium)\u003c\/b\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 16.5507%; height: 39.1875px;\"\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 28.726%; height: 39.1875px;\"\u003e\u003cspan\u003eC₂₁H₂₇N₇O₁₄P₂\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 30.2134%; height: 39.1875px;\"\u003e\u003cspan\u003eC₁₀₁H₁₅₂N₂₈O₂₂S₂\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 23.4338%; height: 39.1875px;\"\u003e\u003cspan\u003eC₁₀H₁₁N₂\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 16.5507%; height: 39.1875px;\"\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 28.726%; height: 39.1875px;\"\u003e\u003cspan\u003e663.43 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 30.2134%; height: 39.1875px;\"\u003e\u003cspan\u003e2174.6 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 23.4338%; height: 39.1875px;\"\u003e\u003cspan\u003e159.21 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 16.5507%; height: 39.1875px;\"\u003e\u003cstrong\u003ePubChem CID\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 28.726%; height: 39.1875px;\"\u003e925\u003c\/td\u003e\n\u003ctd style=\"width: 30.2134%; height: 39.1875px;\"\u003e\n\u003cp\u003e\u003cspan\u003e255386757\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.4338%; height: 39.1875px;\"\u003e\u003cspan\u003e950107\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 16.5507%; height: 39.1875px;\"\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 28.726%; height: 39.1875px;\"\u003e\u003cspan\u003e53-84-9\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 30.2134%; height: 39.1875px;\"\u003e\u003cspan\u003e1627580-64-6\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 23.4338%; height: 39.1875px;\"\u003e\u003cspan class=\"Yjhzub\"\u003e42464-96-0\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 80.156px;\"\u003e\n\u003ctd style=\"width: 16.5507%; height: 80.156px;\"\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 28.726%; height: 80.156px;\"\u003e\u003cspan\u003eβ-Nicotinamide adenine dinucleotide, DPN, Coenzyme I, Diphosphopyridine nucleotide\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 30.2134%; height: 80.156px;\"\u003e\u003cspan\u003eHuman MOTS-c, UNII-A5CV6JFB78, MOTS-c trifluoroacetate salt\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 23.4338%; height: 80.156px;\"\u003e\u003cspan\u003e5-amino-1-methylquinolinium, SCHEMBL6403148, CHEMBL4116828, ZMJBCEIHNOWCMC-UHFFFAOYSA-O, STL196667\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947415290011,"sku":"NAD-MOTS-5AM-120MG","price":33329.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/NAD-MOTS-5AM-120MG-nad-mots-c-5-amino-1mq-blend-120mg-100mg-10mg-10mg-RET.jpg?v=1770933379"},{"product_id":"n-acetyl-selank-amidate-20mg-biolongevity-labs","title":"N-Acetyl Selank Amidate X20mg","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003eSelank is a synthetic heptapeptide (Thr‑Lys‑Pro‑Arg‑Pro‑Gly‑Pro) derived from the natural regulatory peptide tuftsin. It is primarily studied for its anxiolytic (anti‑anxiety), nootropic (cognitive‑enhancing), immunomodulatory, and antiviral properties. Its activity is linked to modulation of the GABAergic system and influence on gene expression.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eN‑Acetyl Selank Amidate is a modified version of Selank, engineered through N‑terminal acetylation and C‑terminal amidation. These structural modifications enhance stability, potency, and blood‑brain barrier penetration, extending biological activity compared to standard Selank.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGABAergic Modulation:\u003c\/strong\u003e Influences GABA receptor activity, contributing to anxiolytic effects.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGene Expression Regulation:\u003c\/strong\u003e Alters transcriptional activity linked to stress response and cognition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroprotective Effects:\u003c\/strong\u003e Supports resilience against stress‑induced neuronal changes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnhanced Stability:\u003c\/strong\u003e Acetylation and amidation confer resistance to enzymatic degradation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImproved Bioavailability:\u003c\/strong\u003e Structural modifications increase potency and CNS penetration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAnxiety and stress‑related disorder models\u003c\/li\u003e\n\u003cli\u003eCognitive enhancement and memory studies\u003c\/li\u003e\n\u003cli\u003eImmunomodulation and antiviral research\u003c\/li\u003e\n\u003cli\u003eNeuroprotection and resilience investigations\u003c\/li\u003e\n\u003cli\u003eExploratory therapeutic studies in mood regulation and psychiatric conditions\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eN‑Acetyl Selank Amidate Research Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSynthetic heptapeptide derived from tuftsin, with anxiolytic and cognitive‑enhancing properties.\u003c\/li\u003e\n\u003cli\u003eModified through acetylation and amidation for improved pharmacological profile.\u003c\/li\u003e\n\u003cli\u003eDemonstrates enhanced stability and potency compared to standard Selank.\u003c\/li\u003e\n\u003cli\u003ePreclinical studies highlight roles in anxiety reduction, cognitive support, and immune modulation.\u003c\/li\u003e\n\u003cli\u003eInvestigated for therapeutic potential in stress‑related disorders, neuroprotection, and antiviral activity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eN-Acetyl Selank Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSelank is a multifaceted peptide with significant potential in treating anxiety, cognitive impairments, and stress-related physiological changes. Its ability to modulate the GABAergic system, enhance cognitive function, and exert immunomodulatory effects positions it as a versatile therapeutic agent.\u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e \u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e\u003cem\u003e\u003cstrong\u003eAnxiolytic and Cognitive Effects\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"markdown-p\"\u003eSelank has demonstrated significant anxiolytic properties, comparable to classical benzodiazepines, without the associated side effects such as dependence and memory \u003cspan class=\"whitespace-nowrap\"\u003eimpairment\u003csup\u003e1\u003c\/sup\u003e. It has been shown to reduce anxiety in conditions of chronic stress and improve cognitive functions, such as memory and attention, particularly in the context of ethanol-induced impairments. The peptide’s ability to regulate brain-derived neurotrophic factor (BDNF) content in the hippocampus and prefrontal cortex is thought to contribute to its cognitive-enhancing effects\u003csup\u003e2\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e \u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e\u003cem\u003e\u003cstrong\u003eImmunomodulatory and Antiviral Properties\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"markdown-p\"\u003eBeyond its neurological effects, Selank also exhibits immunomodulatory and antiviral properties. It can significantly alter the expression of genes related to chemokines, cytokines, and their receptors, suggesting a role in immune response \u003cspan class=\"whitespace-nowrap\"\u003emodulation\u003csup\u003e3\u003c\/sup\u003e. These properties make Selank a promising candidate for therapeutic applications beyond anxiety and cognitive disorders.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e \u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e\u003cem\u003e\u003cstrong\u003eStress Mitigation and Physiological Effects\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"markdown-p\"\u003eSelank has been shown to mitigate stress-induced physiological changes. In animal models, it reduces stress-related morphological changes in organs such as the liver and colon, indicating its potential to alleviate stress-induced \u003cspan class=\"whitespace-nowrap\"\u003edamage. These effects are likely due to its multifunctional biological activity, which includes reducing corticosterone levels and promoting adaptation to stress\u003csup\u003e4\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cp\u003eVyunova, T., Andreeva, L., Shevchenko, K., \u0026amp; Myasoedov, N. (2018). Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity.. \u003cem\u003eProtein and peptide letters\u003c\/em\u003e, 25 10, 914-923 . \u003ca href=\"https:\/\/doi.org\/10.2174\/0929866525666180925144642\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.2174\/0929866525666180925144642\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eKolik, L., Nadorova, A., Antipova, T., Kruglov, S., Kudrin, V., \u0026amp; Durnev, A. (2019). Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats. \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e, 167, 641 – 644. \u003ca href=\"https:\/\/doi.org\/10.1007\/s10517-019-04588-9\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1007\/s10517-019-04588-9\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eKolomin, T., Mikhalskaia, P., \u0026amp; Sedelnikova, A. (2023). Changes in Expression of Chemokines, Cytokines and their Receptors under the Action of Selank and its Fragments. \u003cem\u003eJournal of Clinical Physiology and Pathology\u003c\/em\u003e. \u003ca href=\"https:\/\/doi.org\/10.59315\/jiscpp.2023-2-2.16-18\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.59315\/jiscpp.2023-2-2.16-18\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eMukhina, A., Mishina, E., Bobyntsev, I., Medvedeva, O., Svishcheva, M., Kalutskiĭ, P., Andreeva, L., \u0026amp; Myasoedov, N. (2020). Morphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank. \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e, 169, 281 – 285. \u003ca href=\"https:\/\/doi.org\/10.1007\/s10517-020-04868-9\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1007\/s10517-020-04868-9\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003eLabel--\u003cstrong\u003ePeptide Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"bg-bg-100 min-w-full border-separate border-spacing-0 text-sm leading-[1.88888] whitespace-normal\" style=\"width: 99.9363%;\"\u003e\n\u003cthead class=\"border-b-border-100\/50 border-b-[0.5px] text-left\"\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 27.9556%;\"\u003eProperty\u003c\/th\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 71.5313%;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 27.9556%;\"\u003ePeptide Sequence\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 71.5313%;\"\u003eAc-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 27.9556%;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 71.5313%;\"\u003eC33H57N11O9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 27.9556%;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 71.5313%;\"\u003e751.9 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 27.9556%;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 71.5313%;\"\u003e129954-34-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 27.9556%;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 71.5313%;\"\u003e11765600\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 27.9556%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 71.5313%;\"\u003eSelank, 129954-34-3, Selanc, Thr-Lys-Pro-Arg-Pro-Gly-Pro, TP-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eN-Acetyl Selank Peptide Structure\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg data-opt-id=\"464834253\" data-opt-src=\"https:\/\/www.peptidesciences.com\/media\/wysiwyg\/Selank_Structure.png\" decoding=\"async\" class=\"\" src=\"https:\/\/www.peptidesciences.com\/media\/wysiwyg\/Selank_Structure.png\" alt=\"Molecule\" width=\"369\" height=\"369\" title=\"N-Acetyl Selank Amidate (20mg) 3\" data-opt-lazy-loaded=\"true\" data-opt-optimized-width=\"369\" data-opt-optimized-height=\"369\"\u003e\u003c\/p\u003e\n\u003cp\u003eSource\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Selank\" rel=\"noopener\" target=\"_blank\"\u003ePubChem\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947416731803,"sku":"NASEL-20MG","price":15697.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/NASEL-20MG-n-acetyl-selank-amidate-20mg-RET.jpg?v=1770933379"},{"product_id":"n-acetyl-semax-amidate-20mg-biolongevity-labs","title":"N-Acetyl Semax Amidate X 20mg","description":"\u003cp\u003eDescription--N‑Acetyl Semax Amidate is a stabilized synthetic heptapeptide derived from the ACTH(4‑7) fragment, structurally defined as Ac‑Met‑Glu‑His‑Phe‑Pro‑Gly‑Pro‑NH₂. It incorporates N‑terminal acetylation and C‑terminal amidation, modifications that enhance resistance to enzymatic degradation and extend biological activity. These structural adaptations increase peptide stability, prolong half‑life (approximately 30 minutes longer than standard Semax), and improve neuroprotective efficacy.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMelanocortin Receptor Modulation:\u003c\/strong\u003e Interacts with MC₄ and MC₅ receptors, influencing pathways linked to cognition, stress response, and neuroprotection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurotransmitter Regulation:\u003c\/strong\u003e Modulates serotonin and dopamine activity, supporting mood and cognitive processes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBDNF Upregulation:\u003c\/strong\u003e Enhances brain‑derived neurotrophic factor (BDNF) expression, promoting neuroplasticity and regeneration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStructural Stability:\u003c\/strong\u003e N‑acetylation and amidation confer resistance to enzymatic breakdown, extending biological activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtended Half‑Life:\u003c\/strong\u003e Demonstrates longer duration of action compared to standard Semax formulations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCognitive enhancement and memory studies\u003c\/li\u003e\n\u003cli\u003eNeuroprotection and neuroregeneration models\u003c\/li\u003e\n\u003cli\u003eStroke recovery and ischemic injury investigations\u003c\/li\u003e\n\u003cli\u003eNeurodegenerative disease research (e.g., Alzheimer’s, Parkinson’s)\u003c\/li\u003e\n\u003cli\u003eStress response and mood regulation studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eN‑Acetyl Semax Amidate Research Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSynthetic heptapeptide engineered for enhanced stability and efficacy.\u003c\/li\u003e\n\u003cli\u003eStructural modifications (acetylation and amidation) improve resistance to enzymatic degradation.\u003c\/li\u003e\n\u003cli\u003eDemonstrates prolonged half‑life and increased neuroprotective potential compared to standard Semax.\u003c\/li\u003e\n\u003cli\u003ePreclinical studies highlight roles in cognitive enhancement, neurotransmitter modulation, and BDNF upregulation.\u003c\/li\u003e\n\u003cli\u003eInvestigated for therapeutic potential in stroke recovery, neurodegenerative disorders, and stress‑related conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eN-Acetyl Semax Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eN-Acetyl Semax is a synthetic heptapeptide demonstrating neuroprotective and cognitive-enhancing properties. Research indicates its potential in preventing amyloid beta aggregation, providing neuroprotection in ischemic conditions, and enhancing learning and memory functions. The peptide achieves these effects through modulation of neurotransmitter systems and regulation of inflammatory responses, while also showing promise in stress response and immune system function.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eNeuroprotective and Cognitive Effects\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSemax has been shown to prevent the formation of amyloid beta (Aβ) complexes with copper ions, which are implicated in Alzheimer’s disease, inhibiting fibrillogenesis and providing protective effects against\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"whitespace-nowrap\"\u003eneurodegeneration.\u003csup\u003e1\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eThe peptide has additionally been found to exert neuroprotective effects in the context of ischemic brain conditions. It enhances angioprotective, antihypoxic, and neurotrophic activities, which are crucial during the acute period of ischemic stroke. Furthermore, Semax administration has been associated with the modulation of inflammatory responses, promoting anti-inflammatory agents over pro-inflammatory factors, which is beneficial in post-ischemic conditions.\u003csup\u003e2\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eSemax is recognized for its nootropic effects, which include improvements in cognitive functions such as learning and memory. In animal models, Semax has been shown to enhance cognitive recovery in cases of chronic brain ischemia, particularly when used in combination with hopantenic acid.\u003csup\u003e3\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eThe mechanisms underlying the potential cognitive and neuroprotective effects of Semax involve its interaction with various neurotransmitter systems and neurotrophic factors. Semax modulates monoaminergic systems, particularly serotonin and dopamine, which are crucial for mood regulation and cognitive functions. Semax increases serotonin turnover and enhances dopamine release, which can improve learning and memory.\u003csup\u003e4\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eMoreover, Semax has been observed to increase brain-derived neurotrophic factor (BDNF) levels in the basal forebrain, a region associated with cognitive functions, further supporting its role in enhancing cognitive abilities.\u003csup\u003e5\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eSemax and Alzheimer’s Disease (AD)\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSemax is an ACTH-like peptide that has shown the ability to form stable complexes with Cu2+ ions. This property is crucial as it helps prevent the formation of Aβ:Cu2+ complexes, which are implicated in the pathogenesis of AD. Studies have demonstrated that Semax can inhibit fibrillogenesis, particularly the formation of oligomeric species, thereby exhibiting anti-aggregating properties.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eResearch has indicated that Semax can enhance the survival of cholinergic neurons in the basal forebrain, which are known to degenerate in Alzheimer’s dementia. In vitro studies have shown that Semax can increase the survival rate of these neurons by approximately 1.5-1.7 fold and stimulate the activity of choline acetyltransferase, an enzyme critical for acetylcholine \u003cspan class=\"whitespace-nowrap\"\u003esynthesis.\u003csup\u003e6\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eWhile the exact implications of Semax in Alzheimer’s disease require further clarification, its ability to modulate Aβ aggregation and support neuronal survival presents a promising avenue for therapeutic development. Continued research is necessary to explore the full potential of Semax, including its delivery methods and efficacy in clinical settings.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003e\u003cspan class=\"whitespace-nowrap\"\u003eSemax and Stress Response\u003c\/span\u003e\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eSemax has demonstrated significant immunomodulatory properties in models of “social” stress. It effectively restores cellular and humoral immune responses, as well as the phagocytic activity of neutrophils, indicating its potential as an immune corrector under stress conditions\u003csup\u003e7\u003c\/sup\u003e. Additionally, Semax helps in normalizing the levels of pro- and anti-inflammatory cytokines, such as IL-1β, IL-6, and TNF-α, which are typically elevated under stress.\u003csup\u003e8\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eResearch indicates that Semax can block the opioid form of stress-induced analgesia (SIA) without affecting behavioral changes in rats exposed to acute stressors such as inescapable foot shock and forced cold-water swim stress. This suggests that while Semax can modulate pain sensitivity under stress, it does not alter stress-induced behavioral responses.\u003csup\u003e9\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eIn conditions of informational and social stress, Semax exhibits stress-protective effects by reducing stress-induced physiological changes, such as adrenal hypertrophy and gastric mucosa lesions. It also shows antioxidant properties by decreasing lipid peroxidation in immunocompetent organs like the thymus and spleen, thereby mitigating stress-induced immune dysfunction.\u003csup\u003e10\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eImmune and Vascular System Modulation\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eIn a study on rat brain focal ischemia, Semax was found to enhance the expression of genes related to the immune system, particularly those encoding immunoglobulins and chemokines, which are crucial for immune cell activity and \u003cspan class=\"whitespace-nowrap\"\u003emobility.\u003csup\u003e11\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eThis immunomodulatory effect was further supported by research demonstrating Semax’s ability to restore cellular and humoral immune responses and phagocytic activity of neutrophils under “social” stress conditions, indicating its potential as an effective immune corrector.\u003csup\u003e7\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eIn addition to its effects on the immune system, Semax also modulates the vascular system. In ischemic conditions, Semax altered the expression of genes associated with the development and migration of endothelial tissue, smooth muscle cell migration, hematopoiesis, and vasculogenesis.\u003csup\u003e11\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eSciacca, M., Naletova, I., Giuffrida, M., \u0026amp; Attanasio, F. (2022). Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models. \u003cem\u003eACS Chemical Neuroscience\u003c\/em\u003e, 13, 486 – 496. \u003ca href=\"https:\/\/doi.org\/10.1021\/acschemneuro.1c00707\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1021\/acschemneuro.1c00707\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eMiasoedova, N., Skvortsova, V., Nasonov, E., Zhuravleva, E., Grivennikov, I., Arsen’eva, E., \u0026amp; Sukhanov, I. (1999). [Investigation of mechanisms of neuro-protective effect of semax in acute period of ischemic stroke].. \u003cem\u003eZhurnal nevrologii i psikhiatrii imeni S.S. Korsakova\u003c\/em\u003e, 99 5, 15-9.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17603664\/\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/17603664\/\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eKirchev, V. (2023). Cognitive function restoration in rats with chronic brain ischemia using Semax and hopantenic acid comprehensive administration. \u003cem\u003eJournal of Education, Health and Sport\u003c\/em\u003e. \u003ca href=\"https:\/\/doi.org\/10.12775\/jehs.2023.13.04.046\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.12775\/jehs.2023.13.04.046\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eEremin, K., Kudrin, V., Grivennikov, I., Miasoedov, N., \u0026amp; Rayevsky, K. (2004). Effects of Semax on Dopaminergic and Serotoninergic Systems of the Brain. \u003cem\u003eDoklady Biological Sciences\u003c\/em\u003e, 394, 1-3. \u003ca href=\"https:\/\/doi.org\/10.1023\/B:DOBS.0000017114.24474.40\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1023\/B:DOBS.0000017114.24474.40\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eDolotov, O., Karpenko, E., Seredenina, T., Inozemtseva, L., Levitskaya, N., Zolotarev, Y., Kamensky, A., Grivennikov, I., Engele, J., \u0026amp; Myasoedov, N. (2006). Semax, an analogue of adrenocorticotropin (4–10), binds specifically and increases levels of brain‐derived neurotrophic factor protein in rat basal forebrain. \u003cem\u003eJournal of Neurochemistry\u003c\/em\u003e, 97. \u003ca href=\"https:\/\/doi.org\/10.1111\/j.1471-4159.2006.03658.x\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1111\/j.1471-4159.2006.03658.x\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eGrivennikov, I., Dolotov, O., Zolotarev, Y., Andreeva, L., Myasoedov, N., Leacher, L., Black, I., \u0026amp; Dreyfus, C. (2008). Effects of behaviorally active ACTH (4-10) analogue – Semax on rat basal forebrain cholinergic neurons.. \u003cem\u003eRestorative neurology and neuroscience\u003c\/em\u003e, 26 1, 35-43.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18431004\/\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/18431004\/\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eYasenyavskaya, A., Samotrueva, M., Myasoedov, N., \u0026amp; Andreeva, L. (2022). The experimental study of the immunomodulating action of Semax and Selank on the model of „social” stress. \u003cem\u003eEuropean Pharmaceutical Journal\u003c\/em\u003e, 69, 54 – 60. \u003ca href=\"https:\/\/doi.org\/10.2478\/afpuc-2022-0004\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.2478\/afpuc-2022-0004\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eYasenyavskaya, A., Samotrueva, M., Tsibizova, A., Bashkina, O., Andreeva, L., \u0026amp; Myasoedov, N. (2022). Influence of Semax on the Level of Pro- and Anti-Inflammatory Cytokines in Conditions of “Social” Stress. \u003cem\u003eCurrent Drug Therapy\u003c\/em\u003e. \u003ca href=\"https:\/\/doi.org\/10.2174\/1574885517666220831155411\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.2174\/1574885517666220831155411\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eGlazova, N., Myasoedov, N., Limborska, S., Dergunova, L., Kamensky, A., Andreeva, L., Sebentsova, E., Vilensky, D., Manchenko, D., \u0026amp; Levitskaya, N. (2023). Effects of Semax in the Models of Acute Stress. \u003cem\u003eРоссийский физиологический журнал им  И  М  Сеченова\u003c\/em\u003e. \u003ca href=\"https:\/\/doi.org\/10.31857\/s0869813923010053\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.31857\/s0869813923010053\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eSamotrueva, M., Yasenyavskaya, A., Murtalieva, V., Myasoedov, N., \u0026amp; Andreeva, L. (2019). INFLUENCE OF SEMAX ON THE INTENSITY OF LIPID PEROXIDATION IN IMMUNOCOMPETENT ORGANS IN THE CONDITIONS OF “SOCIAL” STRESS. , 19, 188-191. \u003ca href=\"https:\/\/doi.org\/10.17816\/maj191s1188-191\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.17816\/maj191s1188-191\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eMedvedeva, E., Dmitrieva, V., Povarova, O., Limborska, S., Skvortsova, V., Myasoedov, N., \u0026amp; Dergunova, L. (2014). The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis. \u003cem\u003eBMC Genomics\u003c\/em\u003e, 15, 228 – 228. \u003ca href=\"https:\/\/doi.org\/10.1186\/1471-2164-15-228\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1186\/1471-2164-15-228\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003eLabel--\u003cstrong\u003ePeptide Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"bg-bg-100 min-w-full border-separate border-spacing-0 text-sm leading-[1.88888] whitespace-normal\" style=\"width: 99.9363%;\"\u003e\n\u003cthead class=\"border-b-border-100\/50 border-b-[0.5px] text-left\"\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 26.2032%;\"\u003eProperty\u003c\/th\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 73.2837%;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 26.2032%;\"\u003ePeptide Sequence\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 73.2837%;\"\u003eAc-Met-Glu-His-Phe-Pro-Gly-Pro-NH2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 26.2032%;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 73.2837%;\"\u003eC37H51N9O10S\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 26.2032%;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 73.2837%;\"\u003e813.9 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 26.2032%;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 73.2837%;\"\u003e80714-61-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 26.2032%;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 73.2837%;\"\u003e9811102\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 26.2032%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 73.2837%;\"\u003eSemax, 80714-61-0, ACTH (4-7), Pro-Gly-Pro-, MEHFPGP, Met-Glu-His-Phe-Pro-Gly-Pro\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSemax Peptide Structure\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg data-opt-id=\"1529272240\" decoding=\"async\" src=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/image\/imgsrv.fcgi?cid=9811102\u0026amp;t=l\" alt=\"Semax.png\" title=\"N-Acetyl Semax Amidate (20mg) 3\"\u003e\u003c\/p\u003e\n\u003cp\u003eSource:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/9811102#section=2D-Structure\" rel=\"noopener\" target=\"_blank\"\u003ePubChem\u003c\/a\u003e\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003cp\u003e\u003cbr\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947417223323,"sku":"NASEM-20MG","price":8222.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/NASEM-20MG-n-acetyl-semax-amidate-20mg-RET.jpg?v=1770933379"},{"product_id":"nad-500mg-biolongevity-labs","title":"NAD+ X 500mg","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003e\u003cstrong\u003eNAD+ (Nicotinamide Adenine Dinucleotide)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNAD+ is a crucial coenzyme present in all living cells, central to redox reactions and cellular metabolism. It participates in glycolysis, β‑oxidation, and oxidative phosphorylation, while also serving as a substrate for post‑translational modifications such as ADP‑ribosylation and deacetylation. These processes are vital for energy metabolism, DNA repair, gene expression, and stress response. Beyond its metabolic role, NAD+ functions as a signaling molecule, influencing pathways related to cell survival, aging, and disease susceptibility. Levels of NAD+ decline with age, sparking interest in NAD+‑boosting molecules for health and longevity.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnergy Metabolism:\u003c\/strong\u003e Essential cofactor in glycolysis, β‑oxidation, and oxidative phosphorylation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDNA Repair \u0026amp; Genomic Stability:\u003c\/strong\u003e Substrate for PARPs (poly‑ADP ribose polymerases) involved in DNA repair.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpigenetic Regulation:\u003c\/strong\u003e Supports sirtuin‑mediated deacetylation, modulating gene expression and stress resistance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCell Survival \u0026amp; Stress Response:\u003c\/strong\u003e Influences pathways that regulate apoptosis, inflammation, and cellular resilience.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAging \u0026amp; Longevity:\u003c\/strong\u003e Declining NAD+ levels linked to metabolic dysfunction, mitochondrial decline, and age‑related diseases.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMetabolic and mitochondrial biology studies\u003c\/li\u003e\n\u003cli\u003eDNA repair and genomic stability investigations\u003c\/li\u003e\n\u003cli\u003eEpigenetics and sirtuin biology research\u003c\/li\u003e\n\u003cli\u003eAging and longevity studies\u003c\/li\u003e\n\u003cli\u003eNeurodegenerative and age‑related disease models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNAD+ Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNAD+ is involved in redox reactions and serves as a cofactor for various enzymes, including sirtuins and poly(ADP-ribose) polymerases. It plays a significant role in cellular processes such as metabolism, DNA repair, and chromatin remodeling, which are vital for maintaining tissue and metabolic homeostasis. A decline in NAD+ levels is observed with aging, contributing to age-associated diseases like cognitive decline, cancer, and metabolic disorders.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eAging and Longevity\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNAD+ plays a significant role in aging and longevity. Research indicates that restoring NAD+ levels in aged or diseased animals can promote health and extend lifespan. This has led to the exploration of NAD+ precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), which have shown promise in ameliorating age-associated \u003cspan class=\"whitespace-nowrap\"\u003epathophysiologies.\u003csup\u003e1\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eCD38, an NADase, plays a central role in age-related NAD+ decline. Inhibiting CD38 with specific inhibitors like 78c has been shown to reverse NAD+ decline and improve metabolic and physiological parameters in aging models. This includes enhanced glucose tolerance, muscle function, and cardiac performance. The increase in NAD+ levels activates pro-longevity factors such as sirtuins and AMPK, while inhibiting pathways like mTOR-S6K that negatively affect healthspan. This pharmacological strategy highlights the potential of targeting NAD+ metabolism to prevent or reverse age-related metabolic \u003cspan class=\"whitespace-nowrap\"\u003edysfunction.\u003csup\u003e2\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eMetabolic Disorders\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAlterations in NAD+ metabolism are closely linked to the development of metabolic disorders such as diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD). NAD+ levels tend to decrease with aging and under conditions of nutrient disturbance, contributing to these \u003cspan class=\"whitespace-nowrap\"\u003edisorders.\u003csup\u003e3\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eThe imbalance in NAD+\/NADH ratios can lead to impaired cellular stress responses and metabolic dysfunctions, which are characteristic of metabolic diseases.\u003csup\u003e4\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eCardiovascular Diseases\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAging and metabolic stress are associated with a decline in NAD+ levels, which can lead to mitochondrial dysfunction and increased susceptibility to cardiovascular \u003cspan class=\"whitespace-nowrap\"\u003ediseases.\u003csup\u003e5\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eThis depletion is linked to major risk factors such as obesity and hypertension, which contribute to the development of conditions like atherosclerosis and cardiomyopathies.\u003csup\u003e6\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eThe loss of NAD+ with age or stress underscores the importance of maintaining NAD+ levels to prevent cardiovascular dysfunction.\u003csup\u003e7\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eNeurodegenerative Disorders\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eNAD+ participates in redox reactions and NAD+-dependent signaling processes, which are essential for modulating mitochondrial function and reducing oxidative stress, a common feature in neurodegenerative diseases. The activation of NAD+-dependent pathways can enhance cellular resilience against oxidative damage, which is crucial for maintaining neuronal \u003cspan class=\"whitespace-nowrap\"\u003ehealth.\u003csup\u003e8\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"whitespace-nowrap\"\u003eAdditionally, NAD+ influences axonal maintenance and viability, with its metabolism being a target for therapeutic interventions in neurological diseases.\u003csup\u003e9\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eResearch suggests that increasing NAD+ availability can ameliorate mitochondrial dysfunction and reduce neuroinflammation. This has been demonstrated in models of Parkinson’s disease, Alzheimer’s disease, and ALS, where NAD+ enhancement improved mitochondrial function, reduced neuroinflammation, and enhanced cognitive and synaptic functions. The Sirt1\/PGC-1α pathway is one mechanism through which NAD+ exerts its protective effects, highlighting its potential as a therapeutic target.\u003csup\u003e10\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eMitochondrial Function\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNAD+ metabolism is intricately linked to mitochondrial function. It acts as a substrate for sirtuins, a family of NAD+-dependent deacylases, which are key regulators of mitochondrial homeostasis. Increased NAD+ levels and sirtuin activation have been associated with improved mitochondrial function, organismal metabolism, and lifespan across various \u003cspan class=\"whitespace-nowrap\"\u003especies.\u003csup\u003e11\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eThe source and transport of NAD+ within mitochondria have been subjects of debate. Recent studies have identified SLC25A51 as a mammalian mitochondrial NAD+ transporter, which is essential for maintaining mitochondrial NAD+ pools and respiratory function.\u003csup\u003e12\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eThe de novo synthesis of NAD+ has been shown to enhance mitochondrial function, with enzymes like ACMSD playing a critical role in regulating cellular NAD+ levels and sirtuin activity.\u003csup\u003e11\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eCancer Research\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eCancer cells exhibit a unique metabolic phenotype known as the Warburg effect, characterized by increased glycolysis even in the presence of oxygen, which is supported by elevated NAD+ \u003cspan class=\"whitespace-nowrap\"\u003elevels.\u003csup\u003e12\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eThe NAD+ salvage pathway is particularly important in cancer cells, as it is the primary method of NAD+ synthesis, and its inhibition has been shown to induce cancer cell cytotoxicity.\u003csup\u003e13\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eNAD+ metabolism is not only crucial within cancer cells but also affects the tumor microenvironment. NAD+ and its metabolites can influence immune responses and contribute to the creation of an immunosuppressive tumor microenvironment.\u003csup\u003e14\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eEnzymes such as CD38, which consume NAD+, are involved in producing immunosuppressive metabolites like adenosine, further impacting cancer progression and immune evasion.\u003csup\u003e15\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eTargeting NAD+ metabolism presents a promising strategy for cancer treatment. Inhibitors of NAD+ biosynthesis, particularly those targeting nicotinamide phosphoribosyltransferase (NAMPT), have shown potential in preclinical models, although resistance mechanisms such as alternative NAD+ biosynthetic pathways can limit their effectiveness.\u003csup\u003e16\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eRajman, L., Chwalek, K., \u0026amp; Sinclair, D. (2018). Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence.. \u003cem\u003eCell metabolism\u003c\/em\u003e, 27 3, 529-547 . \u003ca href=\"https:\/\/doi.org\/10.1016\/j.cmet.2018.02.011\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/j.cmet.2018.02.011\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eTarragó, M., Chini, C., Kanamori, K., Warner, G., Caride, A., De Oliveira, G., Rud, M., Samani, A., Hein, K., Huang, R., Jurk, D., Cho, D., Boslett, J., Miller, J., Zweier, J., Passos, J., Doles, J., Becherer, D., \u0026amp; Chini, E. (2018). A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline.. \u003cem\u003eCell metabolism\u003c\/em\u003e, 27 5, 1081-1095.e10 . \u003ca href=\"https:\/\/doi.org\/10.1016\/j.cmet.2018.03.016\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/j.cmet.2018.03.016\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eOkabe, K., Yaku, K., Tobe, K., \u0026amp; Nakagawa, T. (2019). Implications of altered NAD metabolism in metabolic disorders. \u003cem\u003eJournal of Biomedical Science\u003c\/em\u003e, 26. \u003ca href=\"https:\/\/doi.org\/10.1186\/s12929-019-0527-8\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1186\/s12929-019-0527-8\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eAmjad, S., Nisar, S., Bhat, A., Shah, A., Frenneaux, M., Fakhro, K., Haris, M., Reddy, R., Patay, Z., Baur, J., \u0026amp; Bagga, P. (2021). Role of NAD+ in regulating cellular and metabolic signaling pathways. \u003cem\u003eMolecular Metabolism\u003c\/em\u003e, 49. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.molmet.2021.101195\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/j.molmet.2021.101195\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eRotllan, N., Camacho, M., Tondo, M., Diarte-Añazco, E., Canyelles, M., Méndez-Lara, K., Benítez, S., Alonso, N., Mauricio, D., Escolà-Gil, J., Blanco-Vaca, F., \u0026amp; Julve, J. (2021). Therapeutic Potential of Emerging NAD+-Increasing Strategies for Cardiovascular Diseases. \u003cem\u003eAntioxidants\u003c\/em\u003e, 10. \u003ca href=\"https:\/\/doi.org\/10.3390\/antiox10121939\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/antiox10121939\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eAbdellatif, M., Sedej, S., \u0026amp; Kroemer, G. (2021). NAD+ Metabolism in Cardiac Health, Aging, and Disease.. \u003cem\u003eCirculation\u003c\/em\u003e, 144 22, 1795-1817 . \u003ca href=\"https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.121.056589\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1161\/CIRCULATIONAHA.121.056589\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLin, Q., Zuo, W., Liu, Y., Wu, K., \u0026amp; Liu, Q. (2021). NAD+ and Cardiovascular Diseases.. \u003cem\u003eClinica chimica acta; international journal of clinical chemistry\u003c\/em\u003e. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.cca.2021.01.012\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/j.cca.2021.01.012\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003ePehar, M., Harlan, B., Killoy, K., \u0026amp; Vargas, M. (2017). Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration.. \u003cem\u003eAntioxidants \u0026amp; redox signaling\u003c\/em\u003e, 28 18, 1652-1668 . \u003ca href=\"https:\/\/doi.org\/10.1089\/ars.2017.7145\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1089\/ars.2017.7145\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eAlexandris, A., \u0026amp; Koliatsos, V. (2023). NAD+, Axonal Maintenance, and Neurological Disease. \u003cem\u003eAntioxidants \u0026amp; Redox Signaling\u003c\/em\u003e, 39, 1167 – 1184. \u003ca href=\"https:\/\/doi.org\/10.1089\/ars.2023.0350\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1089\/ars.2023.0350\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eZhao, Y., Zhang, J., Zheng, Y., Zhang, Y., Zhang, X., Wang, H., Du, Y., Guan, J., Wang, X., \u0026amp; Fu, J. (2021). NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1\/PGC-1α pathway. \u003cem\u003eJournal of Neuroinflammation\u003c\/em\u003e, 18. \u003ca href=\"https:\/\/doi.org\/10.1186\/s12974-021-02250-8\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1186\/s12974-021-02250-8\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eKatsyuba, E., Mottis, A., Ziętak, M., De Franco, F., Van Der Velpen, V., Gariani, K., Ryu, D., Cialabrini, L., Matilainen, O., Liscio, P., Giacchè, N., Stokar-Regenscheit, N., Legouis, D., De Seigneux, S., Ivanisevic, J., Raffaelli, N., Schoonjans, K., Pellicciari, R., \u0026amp; Auwerx, J. (2018). De novo NAD+ synthesis enhances mitochondrial function and improves health. \u003cem\u003eNature\u003c\/em\u003e, 563, 354 – 359. \u003ca href=\"https:\/\/doi.org\/10.1038\/s41586-018-0645-6\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1038\/s41586-018-0645-6\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLuongo, T., Eller, J., Lu, M., Niere, M., Raith, F., Raith, F., Perry, C., Bornstein, M., Oliphint, P., Wang, L., McReynolds, M., Migaud, M., Rabinowitz, J., Johnson, F., Johnsson, K., Johnsson, K., Ziegler, M., Cambronne, X., \u0026amp; Baur, J. (2020). SLC25A51 is a mammalian mitochondrial NAD+ transporter. \u003cem\u003eNature\u003c\/em\u003e, 588, 174 – 179. \u003ca href=\"https:\/\/doi.org\/10.1038\/s41586-020-2741-7\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1038\/s41586-020-2741-7\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eYaku, K., Okabe, K., Hikosaka, K., \u0026amp; Nakagawa, T. (2018). NAD Metabolism in Cancer Therapeutics. \u003cem\u003eFrontiers in Oncology\u003c\/em\u003e, 8. \u003ca href=\"https:\/\/doi.org\/10.3389\/fonc.2018.00622\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3389\/fonc.2018.00622\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eKennedy, B., Sharif, T., Martell, E., Dai, C., Kim, Y., Lee, P., \u0026amp; Gujar, S. (2016). NAD+ salvage pathway in cancer metabolism and therapy.. \u003cem\u003ePharmacological research\u003c\/em\u003e, 114, 274-283 . \u003ca href=\"https:\/\/doi.org\/10.1016\/j.phrs.2016.10.027\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/j.phrs.2016.10.027\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eAudrito, V., Managò, A., Gaudino, F., Sorci, L., Messana, V., Raffaelli, N., \u0026amp; Deaglio, S. (2019). NAD-Biosynthetic and Consuming Enzymes as Central Players of Metabolic Regulation of Innate and Adaptive Immune Responses in Cancer. \u003cem\u003eFrontiers in Immunology\u003c\/em\u003e, 10. \u003ca href=\"https:\/\/doi.org\/10.3389\/fimmu.2019.01720\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3389\/fimmu.2019.01720\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eMyong, S., Nguyen, A., \u0026amp; Challa, S. (2024). Biological Functions and Therapeutic Potential of NAD+ Metabolism in Gynecological Cancers. \u003cem\u003eCancers\u003c\/em\u003e, 16. \u003ca href=\"https:\/\/doi.org\/10.3390\/cancers16173085\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/cancers16173085\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eGhanem, M., Caffa, I., Monacelli, F., \u0026amp; Nencioni, A. (2024). Inhibitors of NAD+ Production in Cancer Treatment: State of the Art and Perspectives. \u003cem\u003eInternational Journal of Molecular Sciences\u003c\/em\u003e, 25. \u003ca href=\"https:\/\/doi.org\/10.3390\/ijms25042092\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/ijms25042092\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003e\u003cbr\u003eLabel--\u003cstrong\u003eProduct Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"bg-bg-100 min-w-full border-separate border-spacing-0 text-sm leading-[1.88888] whitespace-normal\"\u003e\n\u003cthead class=\"border-b-border-100\/50 border-b-[0.5px] text-left\"\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eProperty\u003c\/th\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003ePresentation\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eVial\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eC21H27N7O14P2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003e663.43 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003e53-84-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003e925\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\"\u003e53-84-9, beta-nicotinamide adenine dinucleotide, Endopride, alpha-Diphosphopyridine nucleotide, 7298-93-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp style=\"text-align: center;\"\u003e \u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cstrong\u003eNAD+ Structure\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" title=\"NAD+ (500mg) 3\" alt=\"beta-Nicotinamide adenine dinucleotide.png\" src=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/image\/imgsrv.fcgi?cid=925\u0026amp;t=l\" decoding=\"async\" data-opt-id=\"1529272240\"\u003e\u003c\/p\u003e\n\u003cp\u003eSource: \u003ca rel=\"noopener\" href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/925#section=2D-Structure\" target=\"_blank\"\u003ePubChem\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947418992795,"sku":"NAD-500MG","price":15524.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/NAD-500MG-nad-500mg-RET.jpg?v=1770933379"},{"product_id":"pinealon-20mg-biolongevity-labs","title":"Pinealon X 20mg","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003ePinealon is a synthetic tripeptide bioregulator composed of L‑glutamic acid, L‑aspartic acid, and L‑arginine (Glu‑Asp‑Arg \/ EDR). Classified as a cytogen, it interacts directly with DNA to modulate gene expression, distinguishing it from receptor‑dependent peptides. Developed through Russian research on neuroprotective agents, Pinealon has been studied for its potential neuroprotective and antioxidative properties, particularly in relation to oxidative stress and neurodegenerative conditions. Its activity is associated with the pineal gland and central nervous system.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDNA Interaction:\u003c\/strong\u003e Functions as a cytogen, directly influencing gene expression.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroprotection:\u003c\/strong\u003e Investigated for protective effects against oxidative stress in neuronal cells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntioxidative Activity:\u003c\/strong\u003e Shown to reduce oxidative damage markers in experimental models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCNS Modulation:\u003c\/strong\u003e Targets pineal gland and central nervous system pathways.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMulti‑Modal Activity:\u003c\/strong\u003e Distinct from receptor‑mediated peptides, offering broader regulatory potential.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNeurodegenerative disease models (Alzheimer’s, Parkinson’s)\u003c\/li\u003e\n\u003cli\u003eOxidative stress and free radical biology studies\u003c\/li\u003e\n\u003cli\u003eGene expression and DNA regulation research\u003c\/li\u003e\n\u003cli\u003ePineal gland and circadian rhythm investigations\u003c\/li\u003e\n\u003cli\u003eExploratory therapeutic studies in cognitive decline and aging\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePinealon Research Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSynthetic tripeptide (Glu‑Asp‑Arg) developed in Russia as part of peptide bioregulator research.\u003c\/li\u003e\n\u003cli\u003eClassified as a cytogen due to its direct DNA interaction.\u003c\/li\u003e\n\u003cli\u003eStudied for neuroprotective, antioxidative, and gene‑modulating properties.\u003c\/li\u003e\n\u003cli\u003eEvidence remains largely preclinical, with limited clinical validation.\u003c\/li\u003e\n\u003cli\u003eProvided in lyophilized form (freeze‑dried, filler‑free) to ensure purity, integrity, and extended shelf life.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePinealon Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePinealon (Glu-Asp-Arg) is a synthetic peptide bioregulator with diverse biological activities, including enhancing learning and memory, exhibiting antioxidant and neuroprotective properties, and regulating neuroinflammatory responses. Its ability to interact with DNA and correct neurochemical disturbances further underscores its potential therapeutic applications in various neurological and metabolic disorders.\u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e \u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e\u003cem\u003e\u003cstrong\u003eEffects on Learning and Memory\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"markdown-p\"\u003ePinealon has been shown to have a significant impact on learning and memory, particularly in the context of experimental diabetes in rats. In a study using the Morris water maze, pinealon was administered at various doses, and it was found that a dose of 100 ng\/kg had the most positive effect on maintaining acquired skills during streptozotocin-induced diabetes. This dose also resulted in minimal changes in the expression levels of NMDA receptor subunit genes, suggesting a protective effect on cognitive \u003cspan class=\"whitespace-nowrap\"\u003efunctions\u003c\/span\u003e.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e \u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e\u003cem\u003e\u003cstrong\u003eCellular Penetration and DNA Interaction\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"markdown-p\"\u003ePinealon, along with other short peptides, has demonstrated the ability to penetrate animal cells and interact with nuclear components, including DNA. This interaction is sequence-specific, with pinealon showing a preference for binding to CAG-containing sequences. Such interactions suggest that pinealon may play a role in regulating gene activity through epigenetic \u003cspan class=\"whitespace-nowrap\"\u003emechanisms\u003c\/span\u003e.\u003csup\u003e2\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e \u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e\u003cem\u003e\u003cstrong\u003eAntioxidant and Neuroprotective Properties\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"markdown-p\"\u003ePinealon exhibits antioxidant properties by restricting reactive oxygen species (ROS) accumulation and reducing necrotic cell death in various cell types. It also modulates the cell cycle, indicating its potential to interact directly with the cell genome beyond its antioxidant \u003cspan class=\"whitespace-nowrap\"\u003eactivity\u003c\/span\u003e.\u003csup\u003e3\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eAdditionally, pinealon has been shown to protect rat offspring from prenatal hyperhomocysteinemia, improving cognitive function and resistance to oxidative stress in \u003cspan class=\"whitespace-nowrap\"\u003eneurons\u003c\/span\u003e.\u003csup\u003e4\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e \u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e\u003cem\u003e\u003cstrong\u003eAntihypoxic Effects\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"markdown-p\"\u003ePinealon has demonstrated pronounced antihypoxic properties, particularly in models of hypobaric hypoxia. It enhances neuronal resistance to hypoxic stress by stimulating internal antioxidative enzyme systems and potentially limiting excitotoxic \u003cspan class=\"whitespace-nowrap\"\u003eeffects\u003c\/span\u003e.\u003csup\u003e5\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e \u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e\u003cem\u003e\u003cstrong\u003eRegulation of Neuroinflammatory Responses\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"markdown-p\"\u003eIn conditions of sharp hypoxic hypoxia, pinealon has been observed to promote neurogenesis and reduce neuroinflammatory reactions, suggesting its potential in managing brain hypoxia and related \u003cspan class=\"whitespace-nowrap\"\u003econditions\u003c\/span\u003e.\u003csup\u003e6\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e \u003c\/p\u003e\n\u003cp class=\"mt-6 mb-3 base-bold\"\u003e\u003cem\u003e\u003cstrong\u003eCorrection of Neurochemical Disturbances\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"markdown-p\"\u003ePinealon has been effective in correcting hyperhomocysteinemia-induced disturbances in the diurnal dynamics of norepinephrine content in the hypothalamus, which is crucial for reproductive function in female rats. This highlights its neuroprotective effects and therapeutic potential in reproductive\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"whitespace-nowrap\"\u003ehealth research\u003c\/span\u003e.\u003csup\u003e7\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp class=\"markdown-p\"\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eKarantysh, G., Fomenko, M., Menzheritskii, A., Prokof’ev, V., Ryzhak, G., \u0026amp; Butenko, E. (2020). Effect of Pinealon on Learning and Expression of NMDA Receptor Subunit Genes in the Hippocampus of Rats with Experimental Diabetes. \u003cem\u003eNeurochemical Journal\u003c\/em\u003e, 14, 314-320. \u003ca href=\"https:\/\/doi.org\/10.1134\/S181971242003006X\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1134\/S181971242003006X\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eFedoreyeva, L., Kireev, I., Khavinson, V., \u0026amp; Vanyushin, B. (2011). Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA. \u003cem\u003eBiochemistry (Moscow)\u003c\/em\u003e, 76, 1210-1219. \u003ca href=\"https:\/\/doi.org\/10.1134\/S0006297911110022\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1134\/S0006297911110022\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eKhavinson, V., Ribakova, Y., Kulebiakin, K., Vladychenskaya, E., Kozina, L., Arutjunyan, A., \u0026amp; Boldyrev, A. (2011). Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes.. \u003cem\u003eRejuvenation research\u003c\/em\u003e, 14 5, 535-41 . \u003ca href=\"https:\/\/doi.org\/10.1089\/rej.2011.1172\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1089\/rej.2011.1172\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eArutjunyan, A., Kozina, L., Stvolinskiy, S., Bulygina, Y., Mashkina, A., \u0026amp; Khavinson, V. (2012). Pinealon protects the rat offspring from prenatal hyperhomocysteinemia.. \u003cem\u003eInternational journal of clinical and experimental medicine\u003c\/em\u003e, 5 2, 179-85.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22567179\/\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/22567179\/\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eKozina, L. (2008). [Investigation of antihypoxic properties of short peptides].. \u003cem\u003eAdvances in gerontology = Uspekhi gerontologii\u003c\/em\u003e, 21 1, 61-7.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18546825\/\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/18546825\/\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eMendzheritskii, A., Karantysh, G., Ryzhak, G., \u0026amp; Dem’ianenko, S. (2014). [Regulation of content of cytokines in blood serum and of caspase-3 activity in brains of old rats in model of sharp hypoxic hypoxia with Cortexin and Pinealon].. \u003cem\u003eAdvances in gerontology = Uspekhi gerontologii\u003c\/em\u003e, 27 1, 94-7.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25051764\/\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/25051764\/\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eKorenevskii, A., Arutyunyan, A., Milyutina, Y., Zaloznyaya, I., \u0026amp; Kozina, L. (2014). Pinealon corrects hyperhomocysteinemia-induced disturbances of the diurnal dynamics of hypothalamic norepinephrine content in female rats. \u003cem\u003eNeurochemical Journal\u003c\/em\u003e, 8, 205 – 207. \u003ca href=\"https:\/\/doi.org\/10.1134\/S1819712414030088\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1134\/S1819712414030088\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003eLabel--\u003cstrong\u003ePeptide Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"bg-bg-100 min-w-full border-separate border-spacing-0 text-sm leading-[1.88888] whitespace-normal\" style=\"width: 99.9363%;\"\u003e\n\u003cthead class=\"border-b-border-100\/50 border-b-[0.5px] text-left\"\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 21.7976%;\"\u003eProperty\u003c\/th\u003e\n\u003cth class=\"text-text-000 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 77.8825%;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 21.7976%;\"\u003ePeptide Sequence\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 77.8825%;\"\u003eGlu-Asp-Arg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 21.7976%;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 77.8825%;\"\u003eC15H26N6O8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 21.7976%;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 77.8825%;\"\u003e418.40 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 21.7976%;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 77.8825%;\"\u003e175175-23-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 21.7976%;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 77.8825%;\"\u003e18220191\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"[tbody\u0026gt;\u0026amp;]:odd:bg-bg-500\/10\"\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 21.7976%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd class=\"border-t-border-100\/50 [\u0026amp;:not(:first-child)]:-x-[hsla(var(--border-100) \/ 0.5)] border-t-[0.5px] px-2 [\u0026amp;:not(:first-child)]:border-l-[0.5px]\" style=\"width: 77.8825%;\"\u003eGlutamylaspartylarginine, Glu-Asp-Arg, H-Glu-Asp-Arg-OH, L-Glu-L-Asp-L-Arg, 175175-23-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947420074139,"sku":"PINE-20MG","price":8762.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/PINE-20MG-pinealon-20mg-RET.jpg?v=1770933379"},{"product_id":"bpc-157-tb-500-blend-10mg-biolongevity-labs","title":"BPC-157 TB-500 Blend X 10mg","description":"\u003cp\u003eDescription-- \u003c!--StartFragment --\u003e\u003cstrong\u003eBPC‑157 + TB‑500 Blend (10 mg): \u003c\/strong\u003eThis blend contains 5 mg of BPC‑157 and 5 mg of TB‑500 per vial, combining two peptides with overlapping regenerative properties. Their complementary mechanisms suggest potential synergistic effects in tissue repair, angiogenesis, and inflammation modulation. Both peptides are provided in lyophilized form (freeze‑dried, filler‑free) to preserve purity and stability.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBPC‑157 (Body Protection Compound‑157):\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eDerived from a protective protein in gastric juice; stable in acidic environments.\u003c\/li\u003e\n\u003cli\u003eActs via\u003cstrong\u003e \u003c\/strong\u003egrowth factor‑mediated pathways and nitric oxide systems.\u003c\/li\u003e\n\u003cli\u003eEnhances wound healing, angiogenesis, and tissue repair.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eTB‑500 (Thymosin Beta‑4 fragment):\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eSynthetic peptide representing the active segment of Tβ4.\u003c\/li\u003e\n\u003cli\u003eFunctions through actin‑binding and cellular organization.\u003c\/li\u003e\n\u003cli\u003ePromotes cell migration, angiogenesis, and tissue regeneration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eSynergistic Potential:\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli style=\"list-style-type: none;\"\u003e\n\u003cul\u003e\n\u003cli\u003eBPC‑157 stabilizes blood vessels and promotes microvascular growth.\u003c\/li\u003e\n\u003cli\u003eTB‑500 stimulates endothelial cell migration and actin dynamics.\u003c\/li\u003e\n\u003cli\u003eCombined anti‑inflammatory actions may create a favorable environment for tissue repair.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTissue regeneration and wound healing studies\u003c\/li\u003e\n\u003cli\u003eAngiogenesis and vascular biology research\u003c\/li\u003e\n\u003cli\u003eInflammation modulation and recovery models\u003c\/li\u003e\n\u003cli\u003eMusculoskeletal injury and soft‑tissue repair investigations\u003c\/li\u003e\n\u003cli\u003eExploratory therapeutic studies in recovery and rehabilitation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003e \u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003e\u003cstrong\u003eTB-500 and BPC-157 Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe potential synergistic effects of TB-500 and BPC-157 can be theorized based on their overlapping mechanisms in tissue repair, angiogenesis, and anti-inflammatory responses, as suggested by individual preclinical studies.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eTB-500 primarily promotes cell migration, angiogenesis, and tissue regeneration by upregulating actin dynamics and modulating inflammation\u003csup\u003e1\u003c\/sup\u003e. BPC-157, for its part, enhances wound healing, angiogenesis, and tissue repair through its effects on nitric oxide pathways, vascular endothelial growth factor (VEGF), and anti-inflammatory mechanisms\u003csup\u003e2\u003c\/sup\u003e.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eBoth peptides share overlapping potential in promoting angiogenesis and reducing inflammation, which could amplify healing processes when combined. TB-500’s ability to stimulate endothelial cell migration may complement BPC-157’s role in stabilizing blood vessels and promoting microvascular growth. Their combined anti-inflammatory actions may also create a more favorable environment for tissue repair.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eAlthough direct studies on their combined use are limited, their individual mechanisms suggest a strong theoretical basis for synergistic effects in tissue regeneration and recovery.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cp\u003eSu, L., Kong, X., Loo, S., Gao, Y., Liu, B., Su, X., Dalan, R., Ma, J., \u0026amp; Ye, L. (2022). Thymosin beta-4 improves endothelial function and reparative potency of diabetic endothelial cells differentiated from patient induced pluripotent stem cells. \u003cem\u003eStem cell research \u0026amp; therapy\u003c\/em\u003e, \u003cem\u003e13\u003c\/em\u003e(1), 13.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1186\/s13287-021-02687-x\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1186\/s13287-021-02687-x\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSeiwerth, S., Milavic, M., Vukojevic, J., Gojkovic, S., Krezic, I., Vuletic, L. B., Pavlov, K. H., Petrovic, A., Sikiric, S., Vranes, H., Prtoric, A., Zizek, H., Durasin, T., Dobric, I., Staresinic, M., Strbe, S., Knezevic, M., Sola, M., Kokot, A., Sever, M., … Sikiric, P. (2021). Stable Gastric Pentadecapeptide BPC 157 and Wound Healing. \u003cem\u003eFrontiers in pharmacology\u003c\/em\u003e, \u003cem\u003e12\u003c\/em\u003e, 627533.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.3389\/fphar.2021.627533\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3389\/fphar.2021.627533\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003e\u003cbr\u003eLabel--\u003cstrong\u003eProduct Specifications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cstrong\u003eSpecification\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eBPC-157\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eTB-500\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSequence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eGly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val\u003c\/td\u003e\n\u003ctd\u003eAc-Leu-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC₆₂H₉₈N₁₆O₂₂\u003c\/td\u003e\n\u003ctd\u003eC₃₈H₆₈N₁₂O₁₄\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1419.5 g\/mol\u003c\/td\u003e\n\u003ctd\u003e889.0 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePubChem CID\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e9941957\u003c\/td\u003e\n\u003ctd\u003e62707662\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e137525-51-0\u003c\/td\u003e\n\u003ctd\u003e885340-08-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003ePL-14736, Body-Protection Compound-157, Bepecin\u003c\/td\u003e\n\u003ctd\u003eThymosin-β4 fragment 17-23, TB-500 acetate, Ac-LKKTETQ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947425382555,"sku":"BPTB55","price":14096.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/BPTB55-bpc-157-tb-500-blend-10mg-RET.jpg?v=1770933379"},{"product_id":"dsip-delta-sleep-inducing-peptide-5mg-biolongevity-labs","title":"DSIP - Delta Sleep-Inducing Peptide X 5mg","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003e\u003cstrong\u003eDSIP (Delta Sleep‑Inducing Peptide): \u003c\/strong\u003eIt is a naturally occurring nonapeptide (Trp‑Ala‑Gly‑Gly‑Asp‑Ala‑Ser‑Gly‑Glu) first isolated in rabbits in the 1970s. It is named for its ability to promote slow‑wave (delta) sleep in experimental animals and has been studied across species including humans, rabbits, rats, and mice. Research suggests DSIP may play broader roles in neuroendocrine regulation, stress response, pain modulation, and immune function.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSleep Regulation:\u003c\/strong\u003e Enhances delta and spindle EEG activity, supporting deep sleep stages.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroendocrine Effects:\u003c\/strong\u003e Investigated for modulation of hypothalamic–pituitary function and stress response.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePain Modulation:\u003c\/strong\u003e Preclinical studies suggest potential analgesic properties.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune Function:\u003c\/strong\u003e Early research indicates possible immunomodulatory activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystemic Role:\u003c\/strong\u003e Mechanism of action remains under investigation, with evidence pointing to multiple physiological pathways.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSleep physiology and insomnia research\u003c\/li\u003e\n\u003cli\u003eNeuroendocrine and stress regulation studies\u003c\/li\u003e\n\u003cli\u003ePain and nociception models\u003c\/li\u003e\n\u003cli\u003eImmune system investigations\u003c\/li\u003e\n\u003cli\u003eExploratory therapeutic studies in depression and chronic conditions\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDSIP Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003eDelta sleep-inducing peptide (DSIP) is a neuropeptide consisting of nine amino acids (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) that was first isolated from the cerebral venous blood of rabbits during sleep in the 1970s.\u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003e \u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003eAs its name suggests, DSIP was initially identified for its apparent ability to promote slow-wave (delta) sleep, which is the deepest stage of non-REM sleep. Subsequent research has revealed its effects may be more complex and potentially extend beyond sleep regulation.\u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003eDSIP has been studied for various potential physiological roles, including:\u003c\/p\u003e\n\u003cul class=\"[\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc space-y-1.5 pl-7\"\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003eStress response and adaptation\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003ePain modulation\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003eImmune system regulation\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003eAntioxidant properties\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003eEffects on endocrine function\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003eDSIP has been investigated for potential applications in sleep disorders, pain management, and substance withdrawal syndromes.\u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003e \u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003e\u003cstrong\u003e\u003cem\u003eDSIP and Sleep Regulation\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDSIP is known for its ability to induce delta sleep, a type of non-REM sleep characterized by slow-wave EEG patterns. It has been shown to promote sleep in several species, including rabbits, rats, mice, and humans, with varying effects on REM sleep in \u003cspan class=\"whitespace-nowrap\"\u003ecats\u003csup\u003e1\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eDSIP has been shown to influence neurotransmitter levels, including serotonin (5-HT), glutamate, dopamine, and melatonin, which are crucial for sleep \u003cspan class=\"whitespace-nowrap\"\u003eregulation\u003csup\u003e2\u003c\/sup\u003e. It also affects electrophysiological activity, circadian rhythms, and hormonal levels, indicating its broad impact on physiological processes\u003csup\u003e3\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eDSIP promotes sleep in a species-specific manner, with varying effects on different types of sleep across species. In clinical trials, DSIP has been shown to normalize disturbed sleep and improve alertness and performance during wakefulness\u003csup\u003e4\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eDespite its known effects, the physiological role of DSIP remains unclear, partly due to the lack of identification of its gene and receptor. The existence of DSIP-like peptides with similar biological activity has been hypothesized\u003csup\u003e5\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003e\u003cspan class=\"whitespace-nowrap\"\u003eDSIP and Pain Management\u003c\/span\u003e\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eIn clinical studies, DSIP administration resulted in a notable reduction in pain levels among patients with various pain syndromes, including migraines, vasomotor headaches, chronic tinnitus, and psychogenic pain attacks\u003csup\u003e6\u003c\/sup\u003e. The peptide not only reduced pain severity but also decreased the duration and frequency of pain episodes, suggesting its potential as a therapeutic agent for chronic pain management\u003csup\u003e7\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eDSIP also influences circadian rhythms related to pain perception. In studies with rats, DSIP administration altered the circadian pain threshold, increasing it during both light and dark periods. This effect was not sensitive to naloxone, indicating a distinct mechanism from its opioid-mediated antinociceptive effects\u003csup\u003e8\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan class=\"whitespace-nowrap\"\u003eDSIP and Withdrawal Symptoms\u003c\/span\u003e\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eDSIP has shown promising results in treating withdrawal symptoms in both alcohol and opiate addicts. In a study involving 67 patients, DSIP treatment resulted in a beneficial effect in 48 out of 49 evaluable patients. The treatment led to an immediate and lasting suspension of somatic symptoms, with anxiety resolving more slowly\u003csup\u003e9\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eAnother study with 107 inpatients reported that DSIP treatment led to a marked and rapid improvement in clinical symptoms for 97% of opiate addicts and 87% of alcohol addicts, although anxiety decreased more slowly\u003csup\u003e10\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan class=\"whitespace-nowrap\"\u003eReferences\u003c\/span\u003e\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003ePollard, B., \u0026amp; Pomfrett, C. (2001). Delta sleep-inducing peptide.. \u003cem\u003eEuropean journal of anaesthesiology\u003c\/em\u003e, 18 7, 419-22 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1046\/J.1365-2346.2001.00917.X\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1046\/J.1365-2346.2001.00917.X\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eMu, X., Qu, L., Yin, L., Wang, L., Liu, X., \u0026amp; Liu, D. (2024). Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models. \u003cem\u003eFrontiers in Pharmacology\u003c\/em\u003e, 15. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.3389\/fphar.2024.1439536\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3389\/fphar.2024.1439536\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eGraf, M., \u0026amp; Kastin, A. (1986). Delta-sleep-inducing peptide (DSIP): An update. \u003cem\u003ePeptides\u003c\/em\u003e, 7, 1165-1187. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1016\/0196-9781(86)90148-8\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/0196-9781(86)90148-8\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eSchneider-Helmert, D., \u0026amp; Schoenenberger, G. (1983). Effects of DSIP in man. Multifunctional psychophysiological properties besides induction of natural sleep.. \u003cem\u003eNeuropsychobiology\u003c\/em\u003e, 9 4, 197-206 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1159\/000117964\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1159\/000117964\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eKovalzon, V., \u0026amp; Strekalova, T. (2006). Delta sleep‐inducing peptide (DSIP): a still unresolved riddle. \u003cem\u003eJournal of Neurochemistry\u003c\/em\u003e, 97. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1111\/j.1471-4159.2006.03693.x\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1111\/j.1471-4159.2006.03693.x\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLarbig, W., Gerber, W., \u0026amp; Schoenenberger, G. (1987). Peptidergic Pain Reducing Effects Of The Delta-Sleep-Inducing Peptide (Dsip) In Headache And Other Pain Syndroms. \u003cem\u003eCephalalgia\u003c\/em\u003e, 7, 46 – 48. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1177\/03331024870070S614\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1177\/03331024870070S614\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLarbig, W., Gerber, W., Kluck, M., \u0026amp; Schoenenberger, G. (1984). Therapeutic effects of delta-sleep-inducing peptide (DSIP) in patients with chronic, pronounced pain episodes. A clinical pilot study.. \u003cem\u003eEuropean neurology\u003c\/em\u003e, 23 5, 372-85 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1159\/000115716\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1159\/000115716\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eYehuda, S., \u0026amp; Carasso, R. (1987). The effects of DSIP on pain threshold during light and dark periods in rats are not naloxone-sensitive.. \u003cem\u003eThe International journal of neuroscience\u003c\/em\u003e, 37 1-2, 85-8 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.3109\/00207458708991805\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3109\/00207458708991805\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eDick, P., Grandjean, M., \u0026amp; Tissot, R. (1983). Successful treatment of withdrawal symptoms with delta sleep-inducing peptide, a neuropeptide with potential agonistic activity on opiate receptors.. \u003cem\u003eNeuropsychobiology\u003c\/em\u003e, 10 4, 205-8 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1159\/000118012\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1159\/000118012\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eDick, P., Costa, C., Fayolle, K., Grandjean, M., Khoshbeen, A., \u0026amp; Tissot, R. (1984). DSIP in the treatment of withdrawal syndromes from alcohol and opiates.. \u003cem\u003eEuropean neurology\u003c\/em\u003e, 23 5, 364-71 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1159\/000115715\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1159\/000115715\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003eLabel--\u003cstrong\u003ePeptide Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable style=\"width: 99.9363%;\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth style=\"width: 30.0391%;\"\u003eProperty\u003c\/th\u003e\n\u003cth style=\"width: 69.4478%;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 30.0391%;\"\u003ePeptide Sequence\u003c\/td\u003e\n\u003ctd style=\"width: 69.4478%;\"\u003eTrp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 30.0391%;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"width: 69.4478%;\"\u003eC35H48N10O15\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 30.0391%;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"width: 69.4478%;\"\u003e848.8 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 30.0391%;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"width: 69.4478%;\"\u003e62568-57-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 30.0391%;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"width: 69.4478%;\"\u003e68816\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 30.0391%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 69.4478%;\"\u003eEmideltide, 62568-57-4, DELTA SLEEP INDUCING PEPTIDE, DSIP nonapeptide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947426758811,"sku":"DSIP5","price":7255.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/DSIP5-dsip-delta-sleep-inducing-peptide-5mg-RET.jpg?v=1770933379"},{"product_id":"cjc-1295-and-ipamorelin-blend-10mg-no-dac-biolongevity-labs","title":"CJC 1295 \u0026 Ipamorelin Blend (No DAC) X 10mg","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003eCJC-1295 \u0026amp; Ipamorelin Blend - Growth Hormone Secretagogue Research Complex (10 mg, No DAC)\u003c\/p\u003e\n\u003cp\u003eThis peptide blend combines CJC-1295 (No DAC) and Ipamorelin, two complementary growth hormone secretagogues that act on distinct receptor pathways to amplify GH release.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCJC-1295 (No DAC, 5 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eSynthetic GHRH analog retaining 29 amino acids of native GHRH with four substitutions for stability and receptor affinity.\u003c\/li\u003e\n\u003cli\u003eStimulates pituitary GHRH receptors to increase pulsatile GH secretion.\u003c\/li\u003e\n\u003cli\u003eElevates circulating IGF-1 levels, supporting anabolic and regenerative pathways.\u003c\/li\u003e\n\u003cli\u003eMimics natural GH release patterns without prolonged receptor binding.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eIpamorelin (5 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli style=\"list-style-type: none;\"\u003e\n\u003cul\u003e\n\u003cli\u003eSynthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH₂).\u003c\/li\u003e\n\u003cli\u003eSelective ghrelin receptor agonist that triggers GH release from the pituitary.\u003c\/li\u003e\n\u003cli\u003eHigh potency with minimal off-target hormonal effects (does not significantly affect cortisol, prolactin, or ACTH).\u003c\/li\u003e\n\u003cli\u003eProvides a clean GH stimulation profile compared to other GHS compounds.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynergistic Potential\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDual receptor targeting (GHRH + ghrelin) amplifies GH release.\u003c\/li\u003e\n\u003cli\u003ePromotes IGF-1 elevation while maintaining physiological GH pulsatility.\u003c\/li\u003e\n\u003cli\u003eOffers a balanced approach to studying growth hormone dynamics without excessive endocrine disruption.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGrowth hormone secretion and regulation studies\u003c\/li\u003e\n\u003cli\u003eIGF-1 mediated anabolic and regenerative pathways\u003c\/li\u003e\n\u003cli\u003eComparative analysis of GHRH vs. ghrelin receptor agonism\u003c\/li\u003e\n\u003cli\u003eEndocrine signaling and pituitary function models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCJC 1295 Ipamorelin Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCJC-1295 and ipamorelin have both been researched for their potential to stimulate growth hormone production.\u003c\/p\u003e\n\u003cdiv class=\"relative\"\u003e\n\u003cdiv class=\"mt-4 md:mt-6\"\u003e\n\u003cdiv dir=\"ltr\" class=\"mt-5\"\u003e\n\u003cdiv class=\"prose text-[0.9375rem] sm:text-base leading-[1.5] text-fg-base markdown\"\u003eIpamorelin is a potent and selective GH secretagogue with unique properties that differentiate it from other GH-releasing peptides. Its ability to selectively stimulate GH release without affecting other hormones, along with its potential applications in body composition, make it a promising candidate for further clinical development.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eGrowth Hormone Release\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn GHRH knockout mice, CJC-1295 administration normalized body weight and length, demonstrating its potential in treating growth deficiencies. Daily administration was more effective than less frequent \u003cspan class=\"whitespace-nowrap\"\u003edosing.\u003csup\u003e1\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eIn healthy subjects, CJC-1295 led to dose-dependent increases in GH and IGF-I levels, with effects lasting up to 28 days. In the study, CJC-1295 was well-tolerated with no serious adverse reactions reported, suggesting its potential utility as a therapeutic agent.\u003csup\u003e2\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eIpamorelin mimics the action of ghrelin by binding to the ghrelin receptor (GHSR) in the brain, which leads to the selective stimulation of GH release from the pituitary gland. This mechanism is similar to that of GHRH, but ipamorelin does not significantly affect the release of other hormones such as ACTH or cortisol.\u003csup\u003e3\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eIn animal studies, ipamorelin has been shown to increase longitudinal bone growth and body weight gain in a dose-dependent manner. It enhances GH release without affecting other growth factors like IGF-I, suggesting a direct effect on growth processes.\u003csup\u003e4\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eIn vivo, ipamorelin shows dose-proportional pharmacokinetics with a short half-life and effectively stimulated GH release across various doses.\u003csup\u003e5\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"whitespace-nowrap\"\u003eReferences\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eAlba, M., Fintini, D., Sagazio, A., Lawrence, B., Castaigne, J., Frohman, L., \u0026amp; Salvatori, R. (2006). Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse.. \u003cem\u003eAmerican journal of physiology. Endocrinology and metabolism\u003c\/em\u003e, 291 6, E1290-4 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1152\/AJPENDO.00201.2006\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1152\/AJPENDO.00201.2006\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eTeichman, S., Neale, A., Lawrence, B., Gagnon, C., Castaigne, J., \u0026amp; Frohman, L. (2006). Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.. \u003cem\u003eThe Journal of clinical endocrinology and metabolism\u003c\/em\u003e, 91 3, 799-805 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1210\/JC.2005-1536\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1210\/JC.2005-1536\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eRaun, K., Hansen, B., Johansen, N., Thøgersen, H., Madsen, K., Ankersen, M., \u0026amp; Andersen, P. (1998). Ipamorelin, the first selective growth hormone secretagogue.. \u003cem\u003eEuropean journal of endocrinology\u003c\/em\u003e, 139 5, 552-61 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1530\/EJE.0.1390552\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1530\/EJE.0.1390552\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eJohansen, P., Nowak, J., Skjaerbaek, C., Flyvbjerg, A., Andreassen, T., Wilken, M., \u0026amp; Orskov, H. (1999). Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats.. \u003cem\u003eGrowth hormone \u0026amp; IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society\u003c\/em\u003e, 9 2, 106-13 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1054\/GHIR.1999.9998\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1054\/GHIR.1999.9998\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eGobburu, J., Agersø, H., Jusko, W., \u0026amp; Ynddal, L. (1999). Pharmacokinetic-Pharmacodynamic Modeling of Ipamorelin, a Growth Hormone Releasing Peptide, in Human Volunteers. \u003cem\u003ePharmaceutical Research\u003c\/em\u003e, 16, 1412-1416. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1023\/A:1018955126402\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1023\/A:1018955126402\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cstrong\u003eLabel-- Peptide Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 99.9363%; height: 298.344px;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003cth style=\"width: 29.4596%; height: 10px;\"\u003e\n\u003cp\u003eProperty\u003c\/p\u003e\n\u003c\/th\u003e\n\u003cth style=\"width: 70.2205%; height: 10px;\"\u003e\n\u003cp\u003eValue\u003c\/p\u003e\n\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 35.5938px;\"\u003e\n\u003ctd style=\"width: 29.4596%; height: 35.5938px;\"\u003e\n\u003cp\u003ePeptide Name\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%; height: 35.5938px;\"\u003e\n\u003cp\u003eCJC 1295\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 74.7812px;\"\u003e\n\u003ctd style=\"width: 29.4596%; height: 74.7812px;\"\u003e\n\u003cp\u003ePeptide Sequence\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%; height: 74.7812px;\"\u003e\n\u003cp\u003eTyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala- Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5938px;\"\u003e\n\u003ctd style=\"width: 29.4596%; height: 35.5938px;\"\u003e\n\u003cp\u003eMolecular Formula\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%; height: 35.5938px;\"\u003e\n\u003cp\u003eC165H269N47O46\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5938px;\"\u003e\n\u003ctd style=\"width: 29.4596%; height: 35.5938px;\"\u003e\n\u003cp\u003eMolecular Weight\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%; height: 35.5938px;\"\u003e\n\u003cp\u003e\u003cspan\u003e3647.2\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eg\/mol\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5938px;\"\u003e\n\u003ctd style=\"width: 29.4596%; height: 35.5938px;\"\u003e\n\u003cp\u003eCAS Number\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%; height: 35.5938px;\"\u003e\n\u003cp\u003e446262-90-4\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5938px;\"\u003e\n\u003ctd style=\"width: 29.4596%; height: 35.5938px;\"\u003e\n\u003cp\u003ePubChem CID\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%; height: 35.5938px;\"\u003e\n\u003cp\u003e\u003cspan\u003e91971820\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5938px;\"\u003e\n\u003ctd style=\"width: 29.4596%; height: 35.5938px;\"\u003e\n\u003cp\u003eSynonyms\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%; height: 35.5938px;\"\u003e\n\u003cp\u003eCJC 1295, CJC-1295, 62RC32V9N7, DTXSID501027567\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp style=\"text-align: left;\"\u003e \u003c\/p\u003e\n\u003ctable style=\"width: 99.9363%;\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth style=\"width: 28.8112%;\"\u003eProperty\u003c\/th\u003e\n\u003cth style=\"width: 70.6757%;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 28.8112%;\"\u003ePeptide Name\u003c\/td\u003e\n\u003ctd style=\"width: 70.6757%;\"\u003eIpamorelin\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 28.8112%;\"\u003ePeptide Sequence\u003c\/td\u003e\n\u003ctd style=\"width: 70.6757%;\"\u003eAib-His-D-2Nal-D-Phe-Lys\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 28.8112%;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"width: 70.6757%;\"\u003eC38H49N9O5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 28.8112%;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"width: 70.6757%;\"\u003e711.9 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 28.8112%;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"width: 70.6757%;\"\u003e170851-70-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 28.8112%;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"width: 70.6757%;\"\u003e9831659\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 28.8112%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 70.6757%;\"\u003e170851-70-4, Ipamorelin [INN], NNC-26-0161, UNII-Y9M3S784Z6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eDosage-- \u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947430658203,"sku":"CJIP55","price":11953.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/CJIP55-cjc-1295-and-ipamorelin-blend-10mg-no-dac-RET.jpg?v=1770933379"},{"product_id":"epithalon-20mg-biolongevity-labs","title":"Epithalon X 20mg","description":"\u003cp\u003eDescription--Epithalon (also known as Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the natural pineal peptide epithalamin. It has been studied extensively in longevity and aging research for its role as a bioregulator of cellular processes.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTelomerase Activation:\u003c\/strong\u003e Stimulates telomerase activity, enabling elongation and maintenance of telomeres, the protective caps at the ends of chromosomes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTelomere Length Regulation:\u003c\/strong\u003e Shown to preserve or extend telomere length in preclinical models, potentially delaying cellular senescence.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePineal Gland Modulation:\u003c\/strong\u003e Influences melatonin secretion and circadian rhythm regulation, contributing to systemic anti-aging effects.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntioxidant \u0026amp; Anti-Aging Pathways:\u003c\/strong\u003e Reduces oxidative stress markers and supports mitochondrial function.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGene Expression Regulation:\u003c\/strong\u003e Modulates expression of genes associated with stress resistance, apoptosis, and DNA repair.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLongevity and anti-aging studies\u003c\/li\u003e\n\u003cli\u003eTelomere biology and telomerase modulation\u003c\/li\u003e\n\u003cli\u003eCircadian rhythm and pineal gland function\u003c\/li\u003e\n\u003cli\u003eOxidative stress and mitochondrial resilience\u003c\/li\u003e\n\u003cli\u003eDNA repair and genomic stability investigations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEpithalon Research Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003eEpithalon (also spelled Epitalon) is a synthetic tetrapeptide consisting of four amino acids: Alanine-Glutamic Acid-Aspartic Acid-Glycine (Ala-Glu-Asp-Gly). It was developed and primarily studied in Russia by researchers at the St. Petersburg Institute of Bioregulation and Gerontology.\u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003eThe peptide was designed to mimic epithalamin, a natural extract from the pineal gland. Its key characteristics include:\u003c\/p\u003e\n\u003cul class=\"[\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc space-y-1.5 pl-7\"\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003e\n\u003cp\u003ePurported anti-aging properties\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003e\n\u003cp\u003ePotential to stimulate production of telomerase (an enzyme that can help maintain telomere length)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003e\n\u003cp\u003ePossible regulation of melatonin production and circadian rhythms\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003e\n\u003cp\u003eStudies suggesting effects on immune function\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003eMost research on Epithalon has been conducted in Russia, with some animal studies showing potential lifespan extension effects.\u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003e \u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003e\u003cstrong\u003e\u003cem\u003eTelomere Dynamics and Telomerase Activity\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEpithalon has been shown to activate telomerase in various cell types. Studies indicate that Epithalon can induce the expression of the telomerase catalytic subunit and enhance its enzymatic activity, leading to telomere elongation in human somatic \u003cspan class=\"whitespace-nowrap\"\u003ecells. This activation of telomerase suggests a potential mechanism by which Epithalon may prolong the lifespan of cells and possibly the organism as a whole\u003csup\u003e1\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eResearch demonstrates that Epithalon can significantly retard cellular senescence by reducing telomere shortening and promoting telomere elongation. In aging models, Epithalon-treated cells showed increased telomere length and extended proliferative potential, effectively overcoming the Hayflick limit, which is the typical division limit of somatic cells\u003csup\u003e2\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eLongevity and Anti-Aging Effects\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEpithalon has been shown to increase the lifespan of various organisms. In mice, it increased the lifespan of the last 10% of survivors by 13.3% and the maximum lifespan by \u003cspan class=\"whitespace-nowrap\"\u003e12.3%\u003csup\u003e3\u003c\/sup\u003e. In Drosophila melanogaster, it extended lifespan by 11-16% at very low concentrations\u003csup\u003e4\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eEpithalon can retard cellular senescence by reducing telomere shortening and increasing telomerase activity, which helps prolong cell lifespan\u003csup\u003e5\u003c\/sup\u003e. It decreases the frequency of chromosome aberrations, indicating an antimutagenic effect that may contribute to its geroprotective properties\u003csup\u003e6\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eIn oocytes, Epithalon reduces reactive oxygen species and improves mitochondrial function, which may delay aging processes\u003csup\u003e7\u003c\/sup\u003e. In older primates, Epithalon has been shown to restore age-related hormonal imbalances, such as increasing melatonin levels and improving glucose metabolism\u003csup\u003e8\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eEpithalon influences gene expression related to aging and stress responses, potentially through interactions with DNA\u003csup\u003e9\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eAntioxidant Properties\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEpithalon has been shown to reduce intracellular ROS levels, which are harmful byproducts of cellular metabolism that can lead to oxidative stress and cellular damage\u003csup\u003e10\u003c\/sup\u003e. This reduction in ROS is associated with improved mitochondrial function and decreased apoptosis in aging oocytes, suggesting a protective role against cellular \u003cspan class=\"whitespace-nowrap\"\u003eaging\u003csup\u003e7\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eStudies indicate that Epithalon’s antioxidant properties can surpass those of melatonin in certain contexts. While both compounds are produced by the pineal gland, Epithalon not only acts as a direct antioxidant but also stimulates the production of antioxidant enzymes, providing a broader protective effect\u003csup\u003e10\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eTumor Inhibition\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEpithalon has demonstrated significant inhibitory effects on the development of spontaneous mammary tumors in HER-2\/neu transgenic mice. Studies show that Epithalon treatment reduces both the cumulative number and size of tumors, and decreases the number of mice with multiple \u003cspan class=\"whitespace-nowrap\"\u003etumors\u003csup\u003e11\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eIn rat models, Epithalon has been shown to inhibit colon carcinogenesis induced by 1,2-dimethylhydrazine (DMH). The peptide reduces the number and size of colon tumors, particularly when administered throughout the carcinogenesis process\u003csup\u003e12\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eThe antitumor effects of Epithalon are partly attributed to its ability to downregulate oncogene expression, such as HER-2\/neu in mammary tumors\u003csup\u003e11\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cp\u003eKhavinson, V., Bondarev, I., \u0026amp; Butyugov, A. (2003). Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells. \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e, 135, 590-592. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1023\/A:1025493705728\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1023\/A:1025493705728\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eShi-Liang, T. (2007). Retarding the cellular senescence by Epithalon and changes of telomere length and telomerase activity in the retarding process. \u003cem\u003eJournal of Chongqing College of Education\u003c\/em\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAnisimov, V., Khavinson, V., Popovich, I., Zabezhinski, M., Alimova, I., Rosenfeld, S., Zavarzina, N., Semenchenko, A., \u0026amp; Yashin, A. (2004). Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. \u003cem\u003eBiogerontology\u003c\/em\u003e, 4, 193-202. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1023\/A:1025114230714\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1023\/A:1025114230714\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eKhavinson, V., Izmaylov, D., Obukhova, L., \u0026amp; Malinin, V. (2000). Effect of epitalon on the lifespan increase in Drosophila melanogaster . \u003cem\u003eMechanisms of Ageing and Development\u003c\/em\u003e, 120, 141-149. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1016\/S0047-6374(00)00217-7\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/S0047-6374(00)00217-7\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eKhavinson, V., Bondarev, I., Butyugov, A., \u0026amp; Smirnova, T. (2004). Peptide Promotes Overcoming of the Division Limit in Human Somatic Cell. \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e, 137, 503-506. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1023\/B:BEBM.0000038164.49947.8c\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1023\/B:BEBM.0000038164.49947.8c\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRosenfeld, S., Togo, E., Mikheev, V., Popovich, I., Zabezhinskii, M., Khavinson, V., \u0026amp; Anisimov, V. (2002). Effect of Epithalon on the Incidence of Chromosome Aberrations in Senescence-Accelerated Mice. \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e, 133, 274-276. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1023\/A:1015899003974\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1023\/A:1015899003974\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eYue, X., Liu, S., Guo, J., Meng, T., Zhang, X., Li, H., Song, C., Wang, Z., Schatten, H., Sun, Q., \u0026amp; Guo, X. (2022). Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro. \u003cem\u003eAging (Albany NY)\u003c\/em\u003e, 14, 3191 – 3202. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.18632\/aging.204007\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.18632\/aging.204007\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eGoncharova, N., Vengerin, A., Khavinson, V., \u0026amp; Lapin, B. (2005). Pineal peptides restore the age-related disturbances in hormonal functions of the pineal gland and the pancreas. \u003cem\u003eExperimental Gerontology\u003c\/em\u003e, 40, 51-57. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1016\/j.exger.2004.10.004\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/j.exger.2004.10.004\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eKhavinson, V., \u0026amp; Malinin, V. (2005). Gerontological Aspects of Genome Peptide Regulation. . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1159\/isbn.978-3-318-01193-7\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1159\/isbn.978-3-318-01193-7\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eKozina, L., Arutjunyan, A., \u0026amp; Khavinson, V. (2007). Antioxidant properties of geroprotective peptides of the pineal gland.. \u003cem\u003eArchives of gerontology and geriatrics\u003c\/em\u003e, 44 Suppl 1, 213-6 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1016\/J.ARCHGER.2007.01.029\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/J.ARCHGER.2007.01.029\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAnisimov, V., Khavinsov, V., Alimova, I., Provintsiali, M., Manchini, R., \u0026amp; Francheski, K. (2002). Epithalon Inhibits Tumor Growth and Expression of HER-2\/neu Oncogene in Breast Tumors in Transgenic Mice Characterized by Accelerated Aging. \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e, 133, 167-170. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1023\/A:1015555023692\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1023\/A:1015555023692\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAnisimov, V., Khavinson, V., Popovich, I., \u0026amp; Zabezhinski, M. (2002). Inhibitory effect of peptide Epitalon on colon carcinogenesis induced by 1,2-dimethylhydrazine in rats.. \u003cem\u003eCancer letters\u003c\/em\u003e, 183 1, 1-8 . \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1016\/S0304-3835(02)00090-3\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/S0304-3835(02)00090-3\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003eLabel--\u003cstrong\u003ePeptide Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 99.9363%;\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth style=\"width: 29.4596%;\"\u003e\n\u003cp\u003eProperty\u003c\/p\u003e\n\u003c\/th\u003e\n\u003cth style=\"width: 70.2205%;\"\u003e\n\u003cp\u003eValue\u003c\/p\u003e\n\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 29.4596%;\"\u003e\n\u003cp\u003ePeptide Sequence\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%;\"\u003e\n\u003cp\u003eAla-Glu-Asp-Gly\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 29.4596%;\"\u003e\n\u003cp\u003eMolecular Formula\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%;\"\u003e\n\u003cp\u003eC14H22N4O9\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 29.4596%;\"\u003e\n\u003cp\u003eMolecular Weight\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%;\"\u003e\n\u003cp\u003e390.35 g\/mol\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 29.4596%;\"\u003e\n\u003cp\u003eCAS Number\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%;\"\u003e\n\u003cp\u003e307297-39-8\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 29.4596%;\"\u003e\n\u003cp\u003ePubChem CID\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%;\"\u003e\n\u003cp\u003e219042\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 29.4596%;\"\u003e\n\u003cp\u003eSynonyms\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 70.2205%;\"\u003e\n\u003cp\u003e307297-39-8, Glycine, L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-, Ala-Glu-Asp-Gly\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp style=\"text-align: center;\"\u003e\u003cstrong\u003eEpithalon Peptide Structure\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cimg src=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/image\/imgsrv.fcgi?cid=219042\u0026amp;t=l\" alt=\"Epitalon.png\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSource: \u003c\/span\u003e\u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/219042#section=2D-Structure\" rel=\"noopener\" target=\"_blank\"\u003ePubChem\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947432263835,"sku":"EPIT-20MG","price":11421.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/EPIT-20MG-epithalon-20mg-RET.jpg?v=1770933379"},{"product_id":"ghk-cu-copper-peptide-50mg-biolongevity-labs","title":"GHK-Cu Copper Peptide X 50mg","description":"\u003cp\u003eDescription--GHK-Cu (glycine-histidine-lysine copper peptide) is a naturally occurring tripeptide-copper complex found in human plasma, saliva, and urine. Discovered by Dr. Loren Pickart in the 1970s, it functions as a biological regulator with diverse roles in tissue repair, regeneration, and cellular signaling.\u003c\/p\u003e\n\u003cp\u003e\u003c!--StartFragment --\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollagen \u0026amp; Elastin Synthesis: \u003c\/strong\u003eStimulates fibroblasts to increase collagen, elastin, and glycosaminoglycan production, supporting extracellular matrix remodeling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWound Healing \u0026amp; Angiogenesis:\u003c\/strong\u003e Promotes angiogenesis and accelerates tissue repair by enhancing growth factor activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Inflammatory Effects:\u003c\/strong\u003e Downregulates pro-inflammatory cytokines and modulates immune responses in damaged tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntioxidant Protection:\u003c\/strong\u003e Scavenges free radicals and reduces oxidative stress, protecting cells from damage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTissue Remodeling:\u003c\/strong\u003e Regulates metalloproteinase activity, balancing tissue breakdown and regeneration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHair Growth \u0026amp; Skin Renewal:\u003c\/strong\u003e Investigated for stimulating follicle activity and improving dermal regeneration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eWound healing and tissue regeneration models\u003c\/li\u003e\n\u003cli\u003eAnti-aging and dermatological studies\u003c\/li\u003e\n\u003cli\u003eHair growth and follicle stimulation research\u003c\/li\u003e\n\u003cli\u003eAnti-inflammatory and antioxidant pathways\u003c\/li\u003e\n\u003cli\u003eExtracellular matrix remodeling investigations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGHK-Cu Research\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"font-claude-message relative leading-[1.65rem] [\u0026amp;\u0026gt;div\u0026gt;div\u0026gt;:is(p,ul,ol)]:pr-4 md:[\u0026amp;\u0026gt;div\u0026gt;div\u0026gt;:is(p,ul,ol)]:pr-8 [\u0026amp;_pre\u0026gt;div]:bg-bg-300 [\u0026amp;_.ignore-pre-bg\u0026gt;div]:bg-transparent\"\u003e\n\u003cdiv class=\"grid-cols-1 grid gap-2.5 [\u0026amp;_\u0026gt;_*]:min-w-0\"\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003eGHK-Cu\u003cspan\u003e \u003c\/span\u003eis a copper peptide complex that combines the tripeptide GHK (Glycine-Histidine-Lysine) with a copper ion. It occurs naturally in human plasma, with levels that decline with age. This compound has gained attention for several biological properties:\u003c\/p\u003e\n\u003cul class=\"[\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc space-y-1.5 pl-7\"\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003e\n\u003cp\u003eWound healing and tissue regeneration\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003e\n\u003cp\u003eStimulation of collagen production\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003e\n\u003cp\u003eAnti-inflammatory effects\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003e\n\u003cp\u003eAntioxidant properties\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words\"\u003e\n\u003cp\u003ePromotion of blood vessel formation\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003eDue to these properties, GHK-Cu is used in Skincare products, particularly anti-aging formulations, Hair growth treatments, Wound healing applications. Research suggests it works by activating specific genes related to healing and attracting immune cells to injury sites.\u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003e \u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003e\u003cem\u003eSkin Health and Tissue Repair\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eGHK-Cu is widely used in cosmetic products due to its anti-aging properties. It improves skin elasticity, firmness, and reduces fine lines, wrinkles, and \u003cspan class=\"whitespace-nowrap\"\u003ephotodamage\u003csup\u003e1\u003c\/sup\u003e. Studies have demonstrated that GHK-Cu can tighten loose skin, enhance skin density, and reduce hyperpigmentation\u003csup\u003e2\u003c\/sup\u003e. Its ability to inhibit elastase activity further supports the structural integrity of the skin by reducing elastin degeneration\u003csup\u003e3\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eGHK-Cu is a potent wound healing agent, promoting angiogenesis, cell proliferation, and the synthesis of growth factors such as vascular endothelial growth factor (VEGF) and fibroblast growth factor-2 (FGF-2). In vivo studies have shown that GHK-Cu accelerates wound healing in various models, including scald wounds in mice, by enhancing angiogenesis and shortening healing time\u003csup\u003e4\u003c\/sup\u003e. The peptide’s ability to stimulate connective tissue accumulation and collagen synthesis has been demonstrated in experimental wound models\u003csup\u003e5\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003ePulmonary Conditions\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eGHK-Cu has shown promising results in the treatment of bleomycin-induced pulmonary fibrosis, a model for idiopathic pulmonary fibrosis (IPF).\u003c\/p\u003e\n\u003cp\u003eStudies indicate that GHK-Cu can inhibit inflammatory and fibrotic changes by reducing inflammatory cytokines such as TNF-α and IL-6, and by decreasing collagen deposition in lung tissues. It also helps in reversing the imbalance of matrix metalloproteinases (MMP-9) and their inhibitors (TIMP-1), and in preventing epithelial-mesenchymal transition (EMT) through the modulation of Nrf2, NF-κB, and TGF-β1\/Smad2\/3 signaling\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"whitespace-nowrap\"\u003epathways\u003csup\u003e6\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eIn the context of COPD, GHK-Cu has been found to attenuate cigarette smoke-induced pulmonary emphysema and inflammation. It achieves this by reducing oxidative stress and inflammation, as evidenced by decreased levels of inflammatory cytokines and oxidative markers in lung tissues. GHK-Cu also restores antioxidant defenses by upregulating Nrf2 expression, which is crucial for combating oxidative damage in COPD\u003csup\u003e7\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eGHK-Cu has also been studied in models of acute lung injury (ALI), where it demonstrates protective effects by reducing reactive oxygen species (ROS) production and increasing antioxidant enzyme activity. It suppresses inflammatory responses by inhibiting NF-κB and p38 MAPK signaling pathways, reducing lung tissue damage and inflammatory cell infiltration\u003csup\u003e8\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eNeurodegenerative Disorders\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eOne of the critical pathological features of neurodegenerative disorders is protein misfolding and aggregation. GHK-Cu has been shown to prevent copper- and zinc-induced protein aggregation, thereby protecting central nervous system cells from metal-induced toxicity. This property is particularly relevant in conditions like Alzheimer’s disease, where metal ion imbalance contributes to disease \u003cspan class=\"whitespace-nowrap\"\u003eprogression\u003csup\u003e9\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eStudies have demonstrated that GHK-Cu can enhance cognitive performance and provide neuroprotection. In animal models, intranasal administration of GHK-Cu improved cognitive functions, reduced amyloid plaques, and decreased inflammation in the brain, suggesting its potential as a therapeutic agent for Alzheimer’s disease and age-related cognitive decline\u003csup\u003e10\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eGHK-Cu influences gene expression patterns that are crucial for maintaining nervous system health. It has been shown to reset pathological gene expression to healthier states, which may counteract age-related dysregulation of biochemical pathways and support neuronal survival and function\u003csup\u003e11\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cspan class=\"base-md\"\u003eAntibacterial Properties\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"base-md\"\u003eGHK-Cu nanoparticles (GHK-Cu NPs) have been shown to possess significant antibacterial properties. In a study focusing on their application in wound healing, GHK-Cu NPs demonstrated effective antibacterial activity against common bacterial strains such as \u003cem\u003eE. coli\u003c\/em\u003e and \u003cem\u003eS. aureus\u003c\/em\u003e\u003csup\u003e12\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"base-md\"\u003eThe self-assembled nature of these nanoparticles not only addresses the instability issues of GHK-Cu in biological fluids but also enhances their antibacterial efficacy. This makes them a promising candidate for biomedical applications, particularly in wound healing where infection control is crucial.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eAnti-Cancer Activities and Gene Expression Modulation\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eGHK-Cu exhibits multiple anti-cancer activities. It has been shown to modulate gene expression in cancer cells, such as MCF7 breast cancer cells and PC3 prostate cancer cells. This modulation can reverse the pathological expression of genes associated with cancer progression, thereby potentially restoring tissue integrity and \u003cspan class=\"whitespace-nowrap\"\u003ehealth\u003csup\u003e13\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"whitespace-nowrap\"\u003eRecent studies have highlighted GHK-Cu’s ability to influence gene expression significantly. It can reverse the pathological expression of a substantial percentage of genes in metastasis-prone colon cancer, indicating its potential to alter the course of cancer development. This gene modulation capability extends to shifting gene expression in COPD lungs from a destructive state to one of healthy remodeling, showcasing its broad therapeutic potential\u003csup\u003e13\u003c\/sup\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003ePickart, L. (2008). The human tri-peptide GHK and tissue remodeling. \u003cem\u003eJournal of Biomaterials Science, Polymer Edition\u003c\/em\u003e, 19, 969 – 988. \u003ca href=\"https:\/\/doi.org\/10.1163\/156856208784909435\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1163\/156856208784909435\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003ePickart, L., Vasquez-Soltero, J., \u0026amp; Margolina, A. (2015). GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. \u003cem\u003eBioMed Research International\u003c\/em\u003e, 2015. \u003ca href=\"https:\/\/doi.org\/10.1155\/2015\/648108\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1155\/2015\/648108\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eDymek, M., Olechowska, K., Hąc-Wydro, K., \u0026amp; Sikora, E. (2023). Liposomes as Carriers of GHK-Cu Tripeptide for Cosmetic Application. \u003cem\u003ePharmaceutics\u003c\/em\u003e, 15. \u003ca href=\"https:\/\/doi.org\/10.3390\/pharmaceutics15102485\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/pharmaceutics15102485\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eWang, X., Liu, B., Xu, Q., Sun, H., Shi, M., Wang, D., Guo, M., Yu, J., Zhao, C., \u0026amp; Feng, B. (2017). GHK‐Cu‐liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis. \u003cem\u003eWound Repair and Regeneration\u003c\/em\u003e, 25. \u003ca href=\"https:\/\/doi.org\/10.1111\/wrr.12520\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1111\/wrr.12520\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eMaquart, F., Bellon, G., Chaqour, B., Wegrowski, J., Patt, L., Trachy, R., Monboisse, J., Chastang, F., Birembaut, P., \u0026amp; Gillery, P. (1993). In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds.. \u003cem\u003eThe Journal of clinical investigation\u003c\/em\u003e, 92 5, 2368-76 . \u003ca href=\"https:\/\/doi.org\/10.1172\/JCI116842\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1172\/JCI116842\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eHou, G., \u0026amp; Zhou, X. (2018). Antioxidant and anti-inflammation effect of GHK-Cu in bleomycin-induced pulmonary fibrosis. \u003cem\u003eILD\/DPLD of known origin\u003c\/em\u003e. \u003ca href=\"https:\/\/doi.org\/10.1183\/13993003.CONGRESS-2018.PA2957\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1183\/13993003.CONGRESS-2018.PA2957\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eZhang, Q., Yan, L., Lu, J., \u0026amp; Zhou, X. (2022). Glycyl-L-histidyl-L-lysine-Cu2+ attenuates cigarette smoke-induced pulmonary emphysema and inflammation by reducing oxidative stress pathway. \u003cem\u003eFrontiers in Molecular Biosciences\u003c\/em\u003e, 9. \u003ca href=\"https:\/\/doi.org\/10.3389\/fmolb.2022.925700\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3389\/fmolb.2022.925700\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003ePark, J., Lee, H., Kim, S., \u0026amp; Yang, S. (2016). The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. \u003cem\u003eOncotarget\u003c\/em\u003e, 7, 58405 – 58417. \u003ca href=\"https:\/\/doi.org\/10.18632\/oncotarget.11168\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.18632\/oncotarget.11168\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eMin, J., Sarlus, H., \u0026amp; Harris, R. (2024). Glycyl-l-histidyl-l-lysine prevents copper- and zinc-induced protein aggregation and central nervous system cell death in vitro. \u003cem\u003eMetallomics: Integrated Biometal Science\u003c\/em\u003e, 16. \u003ca href=\"https:\/\/doi.org\/10.1093\/mtomcs\/mfae019\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1093\/mtomcs\/mfae019\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eTucker, M., Liao, G., Park, J., Rosenfeld, M., Wezeman, J., Mangalindan, R., Ratner, D., Darvas, M., \u0026amp; Ladiges, W. (2023). Behavioral and neuropathological features of Alzheimer’s disease are attenuated in 5xFAD mice treated with intranasal GHK peptide. \u003cem\u003ebioRxiv\u003c\/em\u003e. \u003ca href=\"https:\/\/doi.org\/10.1101\/2023.11.20.567908\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1101\/2023.11.20.567908\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003ePickart, L., Vasquez-Soltero, J., \u0026amp; Margolina, A. (2017). The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline. \u003cem\u003eBrain Sciences\u003c\/em\u003e, 7. \u003ca href=\"https:\/\/doi.org\/10.3390\/brainsci7020020\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/brainsci7020020\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eSun, L., Li, A., Hu, Y., Li, Y., Shang, L., \u0026amp; Zhang, L. (2019). Self‐Assembled Fluorescent and Antibacterial GHK‐Cu Nanoparticles for Wound Healing Applications. \u003cem\u003eParticle \u0026amp; Particle Systems Characterization\u003c\/em\u003e, 36. \u003ca href=\"https:\/\/doi.org\/10.1002\/ppsc.201800420\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1002\/ppsc.201800420\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003ePickart, L., Biology, F., \u0026amp; Margolina, A. (2021). Modulation of Gene Expression in Human Breast Cancer MCF7 and Prostate Cancer PC3 Cells by the Human Copper-Binding Peptide GHK-Cu.. , 05, 1-1. \u003ca href=\"https:\/\/doi.org\/10.21926\/OBM.GENET.2102128\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.21926\/OBM.GENET.2102128\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003e\u003cbr\u003eLabel-- \u003cstrong\u003ePeptide Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable style=\"width: 99.9363%;\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth style=\"width: 32.5169%;\"\u003eProperty\u003c\/th\u003e\n\u003cth style=\"width: 67.1632%;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 32.5169%;\"\u003ePeptide Sequence\u003c\/td\u003e\n\u003ctd style=\"width: 67.1632%;\"\u003eGly-His-Lys\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 32.5169%;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"width: 67.1632%;\"\u003eC14H24N6O4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 32.5169%;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"width: 67.1632%;\"\u003e340.38 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 32.5169%;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"width: 67.1632%;\"\u003e49557-75-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 32.5169%;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"width: 67.1632%;\"\u003e73587\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 32.5169%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 67.1632%;\"\u003eglycyl-l-histidyl-l-lysine, 49557-75-7, Gly-his-lys, Prezatide, L-Lysine, glycyl-L-histidyl-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3 style=\"text-align: center;\"\u003e\u003c\/h3\u003e\n\u003ch3 style=\"text-align: center;\"\u003e\u003c\/h3\u003e\n\u003ch3 style=\"text-align: center;\"\u003eGHK-Cu Peptide Structure\u003c\/h3\u003e\n\u003cp\u003e\u003cimg data-opt-id=\"1529272240\" decoding=\"async\" src=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/image\/imgsrv.fcgi?cid=73587\u0026amp;t=l\" alt=\"Prezatide.png\" title=\"GHK-Cu Copper Peptide (50mg) 3\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/p\u003e\n\u003cp\u003eSource:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/73587#section=2D-Structure\" rel=\"noopener\" target=\"_blank\"\u003ePubChem\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947433377947,"sku":"GHK50","price":10350.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/GHK50-ghk-cu-copper-peptide-50mg-RET.jpg?v=1770933379"},{"product_id":"biozapetite-biolongevity-labs","title":"BioZapetite x 90 Vegetable Capsules","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003e\u003cstrong\u003eBioZapetite - Oral GLP-1 Receptor Agonist Research Compound (6 mg)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eBioZapetite delivers orforglipron (6 mg), a first-in-class oral, small-molecule GLP-1 receptor agonist. Unlike peptide-based GLP-1 agonists, orforglipron is orally bioavailable without fasting or water restrictions and demonstrates robust pharmacology in glucose regulation, weight reduction, and cardiometabolic health.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eGlucose Disposal \u0026amp; Insulin Sensitivity\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eEnhances glucose-dependent insulin secretion.\u003c\/li\u003e\n\u003cli\u003eSuppresses glucagon release.\u003c\/li\u003e\n\u003cli\u003eImproves post-prandial glucose control.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eWeight Reduction \u0026amp; Appetite Control\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eActivates central satiety signaling pathways.\u003c\/li\u003e\n\u003cli\u003eSlows gastric emptying.\u003c\/li\u003e\n\u003cli\u003eConsistently reduces caloric intake.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eLipid \u0026amp; Cardiometabolic Health\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eSecondary benefits of weight loss include reductions in blood pressure, triglycerides, and waist circumference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eOral Dosing Convenience\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eHalf-life of ~29–49 hours supports once-daily dosing.\u003c\/li\u003e\n\u003cli\u003eNo need for co-formulated absorption enhancers.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eSafety Profile\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli style=\"list-style-type: none;\"\u003e\n\u003cul\u003e\n\u003cli\u003eConsistent with injectable GLP-1 agonists.\u003c\/li\u003e\n\u003cli\u003ePredominantly mild-to-moderate GI events during titration.\u003c\/li\u003e\n\u003cli\u003eNo hepatic safety signal observed in Phase 3 readouts.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003c!--StartFragment --\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAppetite regulation and body weight studies\u003c\/li\u003e\n\u003cli\u003eGlucose disposal and glycemic control investigations\u003c\/li\u003e\n\u003cli\u003eCardiometabolic risk reduction models\u003c\/li\u003e\n\u003cli\u003eOral small-molecule incretin pharmacology\u003c\/li\u003e\n\u003cli\u003eTranslational safety and GI tolerability research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eGlucose Disposal \u0026amp; Glycemic Control\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eIn a 26-week multicentre trial in type 2 diabetes (n=383), orforglipron reduced HbA1c up to –2.10% and body weight by –10.1 kg, significantly outperforming placebo and matching\/exceeding dulaglutide at higher doses [3]. A 12-week Phase 1b trial reported HbA1c reductions of –1.5% to –1.8% with up to –5.8 kg weight loss [4].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eAppetite \u0026amp; Weight Regulation\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eIn a 36-week obesity study, orforglipron produced –9.4% to –14.7% weight reduction vs –2.3% with placebo, with 46–75% of participants achieving ≥10% weight loss depending on dose [1][2]. Improvements were observed in all prespecified cardiometabolic measures, including waist circumference, blood pressure, and lipid markers.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOral Pharmacology \u0026amp; PK\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eUnlike oral peptide GLP-1 formulations, orforglipron does not require an absorption enhancer\u003cspan\u003e or fasting. AUC and Cmax decrease ~18–24% with food, but this is not clinically significant [6]. Half-life ~29–49 h supports once-daily dosing [4].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSafety \u0026amp; Tolerability\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eAcross Phase 2 and Phase 3 programs, the safety profile was consistent with injectable GLP-1 RAs. GI events (nausea, diarrhea, dyspepsia, vomiting) were most common and dose-related, occurring mainly during titration [3][5]. In Phase 3 (ACHIEVE-1), discontinuations due to AEs were 4–8% vs 1% with placebo, and no hepatic safety signals were detected [5].\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eReferences\u003c\/b\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cspan\u003eWharton S, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eNEJM\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2023. Orforglipron in obesity: –9.4% to –14.7% weight loss at 36 weeks; improvements in cardiometabolic measures. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37351564\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/37351564\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eWharton S, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eNEJM\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2023. Dose-dependent weight loss (–8.6% to –12.6% at 26 weeks) in obesity without diabetes. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37351564\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/37351564\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFrias JP, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eLancet\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2023. Phase 2 T2D: HbA1c ↓ up to –2.10%; weight ↓ up to –10.1 kg; greater efficacy than dulaglutide at high dose. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cardiometabolicforum.com\/publications\/99\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/cardiometabolicforum.com\/publications\/99\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003ePratt E, et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eDiabetes Obes Metab\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2023. Phase 1b: HbA1c –1.5% to –1.8%, weight loss –5.8 kg; t½ ~29–49 h. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37264711\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/37264711\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eLilly Press Release 2025. Phase 3 ACHIEVE-1: HbA1c ↓ –1.3% to –1.6%; weight ↓ –7.9%; GI AEs dose-related; no hepatic signal. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.prnewswire.com\/news-releases\/lillys-oral-glp-1-orforglipron-demonstrated-statistically-significant-efficacy-results-and-a-safety-profile-consistent-with-injectable-glp-1-medicines-in-successful-phase-3-trial-302430985.html\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/www.prnewswire.com\/news-releases\/lillys-oral-glp-1-orforglipron-demonstrated-statistically-significant-efficacy-results-and-a-safety-profile-consistent-with-injectable-glp-1-medicines-in-successful-phase-3-trial-302430985.html\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eMa X, et al. \u003ci\u003eDiabetes Therapy\u003c\/i\u003e 2024. Food-effect PK: AUC\/Cmax ↓ ~18–24% fed vs fasted; overall well-tolerated; no SAEs. \u003ca rel=\"noopener\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s13300-024-01554-1\" target=\"_blank\"\u003ehttps:\/\/link.springer.com\/article\/10.1007\/s13300-024-01554-1\u003c\/a\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003eLabel--\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable border=\"1\" dir=\"ltr\" cellpadding=\"0\" cellspacing=\"0\" style=\"width: 99.9363%; height: 110px;\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"199\" style=\"width: 51.7873%;\"\u003e \u003ccol width=\"117\" style=\"width: 48.2786%;\"\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 58.7812px;\"\u003e\n\u003ctd colspan=\"2\" style=\"height: 58.7812px;\"\u003e\u003cstrong\u003eSupplement Facts\u003cbr\u003eServing Size: 1 Capsule\u003cbr\u003eServings per Container: 90\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 31.625px;\"\u003e\n\u003ctd style=\"height: 31.625px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 31.625px; text-align: center;\"\u003e\u003cstrong\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003eOrforglipron\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e6 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003eDosage--\u003cstrong\u003eFor Research Purposes Only\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv data-widget_type=\"text-editor.default\" data-e-type=\"widget\" data-element_type=\"widget\" data-id=\"610a9cdc\" class=\"elementor-element elementor-element-610a9cdc elementor-widget elementor-widget-text-editor\"\u003e\n\u003cdiv data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\" class=\"ql-block\"\u003e\u003cspan\u003eThis content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\" class=\"ql-block\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\" class=\"ql-block\"\u003e\u003cspan\u003eStore in a dry and dark place at room temperature, out of reach of small children.\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947435212955,"sku":"SUPP-BIOZEP","price":27984.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/SUPP-BIOZEP-biozapetite-RET.jpg?v=1770932969"},{"product_id":"bioignite-biolongevity-labs","title":"BioIgnite x 90 Vegetable Capsules","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003eBioIgnite - Integrated Metabolic Activation Research Formula\u003c\/p\u003e\n\u003cp\u003eBioIgnite is a multi-component research formulation combining a thermogenic amino acid (L-Theanine), a neurostimulant alkaloid (Caffeine), an inflammation-modulating kinase inhibitor (Amlexanox), and a selective β₂-adrenergic agonist (Albuterol). Together, these agents provide a synergistic platform for investigating thermogenesis, glucose metabolism, inflammation, and mitochondrial energy regulation.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eL-Theanine (150 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eActivates AMPK, inducing browning of white adipose tissue.\u003c\/li\u003e\n\u003cli\u003eImproves glucose tolerance and insulin sensitivity.\u003c\/li\u003e\n\u003cli\u003eEnhances mitochondrial fatty acid oxidation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eCaffeine (50 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eAdenosine receptor antagonist; increases cAMP signaling.\u003c\/li\u003e\n\u003cli\u003eStimulates lipolysis, fat oxidation, and resting energy expenditure.\u003c\/li\u003e\n\u003cli\u003eMobilizes free fatty acids for metabolic use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eAmlexanox (50 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eInhibits IKK-ε\/TBK1, reducing metabolic inflammation.\u003c\/li\u003e\n\u003cli\u003eRestores catecholamine responsiveness in adipocytes.\u003c\/li\u003e\n\u003cli\u003eImproves glycemia and reduces fatty liver pathology in preclinical models.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eAlbuterol (3 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003eSelective β₂-adrenergic agonist.\u003c\/li\u003e\n\u003cli\u003eActivates human brown adipose tissue, increasing energy expenditure.\u003c\/li\u003e\n\u003cli\u003eEnhances muscle glucose uptake and fat oxidation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eThermogenesis \u0026amp; Fat Oxidation:\u003c\/strong\u003e AMPK activation, β₂-adrenergic stimulation, and cAMP-driven lipolysis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlucose Disposal \u0026amp; Insulin Sensitivity:\u003c\/strong\u003e Adipose browning, kinase inhibition, and enhanced muscle uptake.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-inflammatory Metabolic Support:\u003c\/strong\u003e Targeting IKK-ε\/TBK1 pathways to reduce metabolic inflammation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMitochondrial \u0026amp; Energy Metabolism:\u003c\/strong\u003e Increased fatty acid oxidation and oxidative tissue activation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe BioIgnite Advantage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMulti-pathway activation of metabolic processes.\u003c\/li\u003e\n\u003cli\u003eSynergistic blend of amino acid, alkaloid, kinase inhibitor, and adrenergic agonist.\u003c\/li\u003e\n\u003cli\u003eSuitable for advanced research into obesity, type 2 diabetes, fatty liver disease, and metabolic syndrome.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eResearch Insights\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eThermogenesis \u0026amp; Fat Oxidation\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eL-Theanine activates AMPK and upregulates \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eUCP1\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e and \u003c\/span\u003e\u003ci\u003e\u003cspan\u003ePRDM16\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e, promoting browning of white adipose tissue and increasing adaptive thermogenesis in obese mice [1][2]. Caffeine increases 24-hour energy expenditure by ~100 kcal when consumed in multiple doses (~600 mg total) [10][11], mediated by enhanced lipolysis and BAT activation [12]. Albuterol (salbutamol) directly stimulates β₂ receptors in human brown fat, acutely raising resting metabolic rate and lipid utilization [6][7]. In rats, the combination of albuterol with caffeine produced significantly greater lean mass gain and fat loss compared to either agent alone [6].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eGlucose Disposal \u0026amp; Insulin Sensitivity\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eL-Theanine supplementation improved glucose tolerance and insulin sensitivity in diet-induced obese mice, lowering plasma triglycerides and cholesterol [2][3]. Amlexanox increased insulin sensitivity in obese mice [4] and improved HbA1c in a subset of type 2 diabetic patients, particularly those with inflammatory adipose signatures [5]. Albuterol enhances glucose uptake in skeletal muscle and BAT during β₂ activation, supporting systemic glucose clearance [6][7].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eAnti-inflammatory Metabolic Support\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAmlexanox inhibits obesity-induced IKK-ε\/TBK1 signaling, a pathway that normally suppresses energy expenditure and promotes adipose inflammation [4]. By blocking this brake, amlexanox restores catecholamine responsiveness in adipocytes, increases FGF21 secretion, and improves fatty liver disease [5]. L-Theanine also exerts antioxidant and anti-inflammatory actions in liver and fat tissue, supporting better insulin receptor signaling [3].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eMitochondrial \u0026amp; Energy Metabolism\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eCaffeine preserves mitochondrial function by upregulating biogenesis pathways via AMPK and catecholamine signaling [10][12]. L-Theanine enhances oxidative metabolism through AMPK–α-ketoglutarate coupling [1]. Albuterol increases mitochondrial uncoupling in BAT and enhances fat oxidation in skeletal muscle [6][7]. Together, these effects foster efficient fuel utilization and higher metabolic rate.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eReferences\u003c\/b\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cspan\u003eFront Endocrinol. 2024 – L-Theanine activates AMPK, drives adipose browning via PRDM16 demethylation.\u003c\/span\u003e\u003ca href=\"https:\/\/www.frontiersin.org\/journals\/endocrinology\/articles\/10.3389\/fendo.2024.1458848\/pdf\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ehttps:\/\/www.frontiersin.org\/journals\/endocrinology\/articles\/10.3389\/fendo.2024.1458848\/pdf\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003ePeng et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eDiabetes\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e. 2021 – L-Theanine increases adaptive thermogenesis \u0026amp; improves insulin sensitivity in obese mice.\u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33863801\/\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/33863801\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFront Nutr. 2022 – L-Theanine intake linked with reduced diabetes risk and improved glucose handling.\u003c\/span\u003e\u003ca href=\"https:\/\/www.frontiersin.org\/journals\/nutrition\/articles\/10.3389\/fnut.2022.853846\/full\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ehttps:\/\/www.frontiersin.org\/journals\/nutrition\/articles\/10.3389\/fnut.2022.853846\/full\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eReilly et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eNat Med\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e. 2013 – Amlexanox inhibits IKK-ε\/TBK1, reverses obesity-induced inflammation, increases energy expenditure.\u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23396211\/\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/23396211\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eOral et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eCell Metab\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e. 2017 – Amlexanox improves HbA1c and fatty liver in inflammatory type 2 diabetes subset.\u003c\/span\u003e\u003ca href=\"https:\/\/www.lsi.umich.edu\/news\/2017-07\/repurposed-asthma-drug-shows-blood-sugar-improvement-among-some-diabetics\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ehttps:\/\/www.lsi.umich.edu\/news\/2017-07\/repurposed-asthma-drug-shows-blood-sugar-improvement-among-some-diabetics\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eSchreiber et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eObesity\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e. 2015 – Albuterol + caffeine combo increases lean mass, reduces fat mass in rats.\u003c\/span\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4551658\/\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ehttps:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4551658\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eStraat et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eCell Rep Med\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e. 2023 – Salbutamol activates human brown adipose tissue and increases whole-body energy expenditure.\u003c\/span\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/368698239_Stimulation_of_the_beta-2-adrenergic_receptor_with_salbutamol_activates_human_brown_adipose_tissue\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ehttps:\/\/www.researchgate.net\/publication\/368698239_Stimulation_of_the_beta-2-adrenergic_receptor_with_salbutamol_activates_human_brown_adipose_tissue\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003ePubMed 33863801 – AMPK activation required for L-Theanine-induced WAT browning.\u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33863801\/\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/33863801\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eLSI Michigan 2017 – Repurposed asthma drug (amlexanox) improves blood sugar and fatty liver in humans.\u003c\/span\u003e\u003ca href=\"https:\/\/www.lsi.umich.edu\/news\/2017-07\/repurposed-asthma-drug-shows-blood-sugar-improvement-among-some-diabetics\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ehttps:\/\/www.lsi.umich.edu\/news\/2017-07\/repurposed-asthma-drug-shows-blood-sugar-improvement-among-some-diabetics\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFront Physiol. 2021 – Caffeine increases energy expenditure and fat oxidation in humans.\u003c\/span\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7889509\/\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ehttps:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7889509\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAstrup et al. 1990 – Caffeine raises 24h energy expenditure in humans.\u003c\/span\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7889509\/\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ehttps:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7889509\/\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eMurphy et al. 2017 – Caffeine antagonism of adenosine receptors activates orexin neurons, driving BAT thermogenesis.\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7889509\/\" rel=\"noopener\" target=\"_blank\"\u003e https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7889509\/\u003c\/a\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eLabel--\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable cellspacing=\"0\" cellpadding=\"0\" dir=\"ltr\" border=\"1\" style=\"width: 99.9363%; height: 147.156px;\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"199\" style=\"width: 47.9632%;\"\u003e \u003ccol width=\"117\" style=\"width: 52.1027%;\"\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 58.7812px;\"\u003e\n\u003ctd colspan=\"2\" style=\"height: 58.7812px;\"\u003e\u003cstrong\u003eSupplement Facts\u003cbr\u003eServing Size: 1 Capsule\u003cbr\u003eServings per Container: 90\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cstrong\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cb\u003eL-Theanine\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e150 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cb\u003eCaffeine\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e50 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cb\u003eAmlexanox\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e50 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"height: 10px;\"\u003e\u003cb\u003eAlbuterol\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center; height: 10px;\"\u003e\u003cspan\u003e3 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003eDosage--\u003cstrong\u003eFor Research Purposes Only\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"elementor-element elementor-element-610a9cdc elementor-widget elementor-widget-text-editor\" data-id=\"610a9cdc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\"\u003e\n\u003cdiv class=\"ql-block\" data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\"\u003e\u003cspan\u003eThis content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"ql-block\" data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\"\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"ql-block\" data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\"\u003e\u003cspan\u003eStore in a dry and dark place at room temperature, out of reach of small children.\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947436490907,"sku":"SUPP-BIOIGN","price":44014.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/SUPP-BIOIGN-bioignite-RET.jpg?v=1770932750"},{"product_id":"bioabsorb-biolongevity-labs","title":"BioAbsorb x 60 Vegetable Capsules","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003e\u003cstrong\u003eBioAbsorb - Integrated Metabolic Research Formula\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBioAbsorb is a next-generation metabolic research complex that combines low-dose metformin, highly bioavailable dihydroberberine, and activated B-complex cofactors. This synergistic blend is designed to amplify glucose disposal, improve lipid and vascular health, enhance mitochondrial energy production, and maintain methylation balance.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eMetformin (125 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eActivates AMPK, improving insulin sensitivity and glucose uptake.\u003c\/li\u003e\n\u003cli\u003eEnhances GLUT-4 translocation for efficient glucose disposal.\u003c\/li\u003e\n\u003cli\u003eProvides metabolic benefits in models of insulin resistance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eDihydroBerberine (125 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eHighly absorbable berberine metabolite with superior bioavailability.\u003c\/li\u003e\n\u003cli\u003eImproves glycemia and lipid profiles.\u003c\/li\u003e\n\u003cli\u003eSupports cardiometabolic health via dual AMPK activation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin B₁ (Thiamin, 12.5 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eCofactor for pyruvate dehydrogenase.\u003c\/li\u003e\n\u003cli\u003eRestores endothelial function and supports vascular health.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin B₂ (Riboflavin, 12.5 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003ePrecursor to FAD.\u003c\/li\u003e\n\u003cli\u003eShown to lower blood pressure in MTHFR-677TT carriers.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin B₅ (Pantethine, 12.5 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003ePrecursor to CoA.\u003c\/li\u003e\n\u003cli\u003eReduces LDL-C and non-HDL-C levels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin B₆ (Pyridoxal-5-Phosphate, 17.5 mg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eActive PLP coenzyme.\u003c\/li\u003e\n\u003cli\u003eDecreases plasma homocysteine concentrations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin B₉ (Methyl-folate, 200 mcg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eActive folate form.\u003c\/li\u003e\n\u003cli\u003eSupports one-carbon metabolism and homocysteine control.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin B₁₂ (Methyl-cobalamin, 50 mcg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli style=\"list-style-type: none;\"\u003e\n\u003cul\u003e\n\u003cli\u003eActive B₁₂ form.\u003c\/li\u003e\n\u003cli\u003eNeuroprotective; improves nerve conduction and methylation balance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Areas\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlucose Disposal \u0026amp; Insulin Sensitivity:\u003c\/strong\u003e Dual AMPK activation via metformin and dihydroberberine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLipid \u0026amp; Cardiovascular Support:\u003c\/strong\u003e Pantethine and riboflavin improve lipid profiles and vascular function.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMitochondrial Energy Metabolism:\u003c\/strong\u003e B-complex cofactors enhance ATP production and enzymatic efficiency.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMethylation \u0026amp; Homocysteine Management:\u003c\/strong\u003e Methyl-folate and methyl-cobalamin maintain one-carbon balance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroprotection \u0026amp; Peripheral Nerve Health:\u003c\/strong\u003e Active B₁₂ supports nerve conduction and resilience.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cstrong\u003eResearch Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eGlucose Disposal \u0026amp; Insulin Sensitivity\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMetformin activates hepatic and skeletal-muscle AMPK, suppressing gluconeogenesis and potentiating insulin-stimulated glucose uptake [1] .  Dihydroberberine, a reduced berberine metabolite with far superior intestinal absorption, demonstrated greater area-under-the-curve exposure and produced acute reductions in post-prandial glucose in a randomized crossover pilot trial [2] .\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eLipid \u0026amp; Endothelial Support\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePantethine (vitamin B₅ derivative) lowered total and LDL cholesterol by 11 % over 16 weeks in a triple-blinded, diet-controlled trial [5] .  Low-dose thiamine reversed hyperglycemia-induced endothelial cell dysfunction in vitro, restoring migration capacity and reducing von Willebrand factor secretion [3] .  Riboflavin supplementation (1.6 mg day⁻¹) produced clinically meaningful blood-pressure reductions in treated hypertensives carrying the MTHFR 677TT polymorphism [4] .\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eMethylation \u0026amp; Homocysteine Management\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIn a randomized controlled trial, combined methyl-folate (5-MTHF), PLP and methyl-cobalamin lowered plasma homocysteine by 30 % and LDL-C by 7.5 % after six months in adults with MTHFR\/MTR\/MTRR polymorphisms [7] .  Independent PLP supplementation has likewise been shown to cut homocysteine while enhancing antioxidant capacity in postsurgical patients [6] .\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eNeuroprotection \u0026amp; Nerve Health\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eA 2020 systematic review and meta-analysis of randomized trials found that mecobalamin (methyl-B₁₂) significantly improved nerve-conduction velocity and overall clinical response in peripheral neuropathy, with a favorable safety profile [8] .\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eReferences\u003c\/b\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cspan\u003eZhou G et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eRole of AMP-activated protein kinase in mechanism of metformin action.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e J Clin Invest. 2001;108:1167-1174. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11602624\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/11602624\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eMoon JM et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eAbsorption kinetics of berberine and dihydroberberine and their impact on glycemia.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eNutrients.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2022;14(1):124. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35010998\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/35010998\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAscher E et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eThiamine reverses hyperglycemia-induced dysfunction in cultured endothelial cells.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eSurgery.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2001;130:851-858. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11685195\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/11685195\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eWilson CP et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eBlood pressure in hypertensive individuals with the MTHFR 677TT genotype is responsive to riboflavin: targeted randomized trial.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eHypertension.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2013;61:1302-1308. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23608654\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/23608654\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eEvans M et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003ePantethine favorably alters LDL and non-HDL cholesterol in low-to-moderate risk subjects.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eVasc Health Risk Manag.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2014;10:89-100. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24600231\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/24600231\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eCheng SB et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eVitamin B-6 supplementation reduces plasma homocysteine in hepatocellular-carcinoma patients after resection.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eBiomed Res Int.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2016;2016:7658981. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27051670\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/27051670\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003ePokushalov E et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eMethylfolate, PLP and methylcobalamin supplementation lowers homocysteine and LDL-C: randomized controlled trial.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eNutrients.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2024;16:1550. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38892484\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/38892484\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eSawangjit R et al. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eEfficacy and safety of mecobalamin on peripheral neuropathy: systematic review and meta-analysis.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eJ Altern Complement Med.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2020;26:1117-1129. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32716261\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/32716261\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003eLabel--\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable style=\"width: 99.9363%; height: 303.907px;\" cellspacing=\"0\" cellpadding=\"0\" dir=\"ltr\" border=\"1\"\u003e\n\u003ccolgroup\u003e \u003ccol style=\"width: 63.0671%;\" width=\"199\"\u003e \u003ccol style=\"width: 36.9968%;\" width=\"117\"\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 58.7812px;\"\u003e\n\u003ctd style=\"height: 58.7812px;\" colspan=\"2\"\u003e\u003cstrong\u003eSupplement Facts\u003cbr\u003eServing Size: 1 Capsule\u003cbr\u003eServings per Container: 60\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"height: 10px; text-align: center;\"\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 10px; text-align: center;\"\u003e\u003cstrong\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cspan\u003eMetformin\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e125 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cspan\u003eDihydroBerberine\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e125 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cspan\u003eVitamin B₁ (Thiamin)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e12.5 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cspan\u003eVitamin B₂ (Riboflavin)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e12.5 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cspan\u003eVitamin B₅ (Pantethine)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e12.5 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cspan\u003eVitamin B₆ (Pyridoxal-5-Phosphate)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e17.5 mg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cspan\u003eVitamin B₉ (Methyl-folate)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e200 mcg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cspan\u003eVitamin B₁₂ (Methyl-cobalamin)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e50 mcg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003eDosage--\u003cstrong\u003eFor Research Purposes Only\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv data-widget_type=\"text-editor.default\" data-e-type=\"widget\" data-element_type=\"widget\" data-id=\"610a9cdc\" class=\"elementor-element elementor-element-610a9cdc elementor-widget elementor-widget-text-editor\"\u003e\n\u003cdiv data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\" class=\"ql-block\"\u003e\u003cspan\u003eThis content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\" class=\"ql-block\"\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\" class=\"ql-block\"\u003e\u003cspan\u003eStore in a dry and dark place at room temperature, out of reach of small children.\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947439931547,"sku":"SUPP-BIOABS","price":22639.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/SUPP-BIOABS-bioabsorb-RET.jpg?v=1770932688"},{"product_id":"bioflow-biolongevity-labs","title":"BioFlow x 60 Vegetable Capsules","description":"\u003cp\u003eDescription--\u003cstrong\u003eBioFlow - Advanced Metabolic, Vascular, and Cognitive Research Complex\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBioFlow is an integrated research formulation combining low-dose tesofensine, taurine, and magnesium L-threonate. This multi-target blend is designed to support investigations into appetite regulation, vascular endothelial function, and cognitive resilience.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanistic Claims\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eTesofensine (250 mcg per capsule)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003ePotent triple monoamine reuptake inhibitor (dopamine, serotonin, norepinephrine).\u003c\/li\u003e\n\u003cli\u003eSuppresses appetite and induces weight loss in diet-induced obese models.\u003c\/li\u003e\n\u003cli\u003eNormalizes forebrain dopamine signaling, improving metabolic efficiency.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eTaurine (500 mcg per capsule)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eAntioxidant and endothelial protector.\u003c\/li\u003e\n\u003cli\u003eRestores flow-mediated dilation (FMD) and reduces arterial stiffness.\u003c\/li\u003e\n\u003cli\u003eEnhances vascular function in models of early endothelial dysfunction.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\u003cstrong\u003eMagnesium L-Threonate (350 mcg per capsule)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli style=\"list-style-type: none;\"\u003e\n\u003cul\u003e\n\u003cli\u003eElevates brain magnesium concentrations.\u003c\/li\u003e\n\u003cli\u003eEnhances synaptic plasticity, long-term potentiation (LTP), and memory formation.\u003c\/li\u003e\n\u003cli\u003eReduces amyloid plaque burden and rescues synaptic density in Alzheimer’s models.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Areas\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAppetite suppression and weight management via central monoamine modulation.\u003c\/li\u003e\n\u003cli\u003eVascular endothelial support and blood pressure regulation.\u003c\/li\u003e\n\u003cli\u003eCognitive enhancement, memory improvement, and synaptic resilience.\u003c\/li\u003e\n\u003cli\u003eNeuroprotection in aging and neurodegenerative disease models.\u003c\/li\u003e\n\u003cli\u003eMetabolic syndrome investigations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe BioFlow Advantage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDirect mechanistic activity across metabolic, vascular, and cognitive domains.\u003c\/li\u003e\n\u003cli\u003eSynergistic blend of three complementary compounds.\u003c\/li\u003e\n\u003cli\u003eSuitable for advanced preclinical studies targeting obesity, cardiovascular wellness, and cognitive aging.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003c\/p\u003e\n\u003cp class=\"wpt-acc-title\"\u003e\u003cstrong\u003eResearch\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv aria-labelledby=\"tab-title-research\" role=\"tabpanel\" id=\"tab-research\" class=\"woocommerce-Tabs-panel woocommerce-Tabs-panel--research panel entry-content wc-tab\"\u003e\n\u003cp\u003e\u003cem\u003eAppetite Suppression \u0026amp; Weight Loss\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTesofensine acts as a potent triple monoamine reuptake inhibitor, reducing food intake and inducing significant weight loss in diet-induced obese rats, in part by normalizing forebrain dopamine levels [1].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eVascular Endothelial Support\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIn young adults with early vascular dysfunction (e.g., type 1 diabetics), two weeks of taurine supplementation reversed endothelial abnormalities—restoring flow-mediated dilation and arterial stiffness to control levels [2].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eCognitive Enhancement \u0026amp; Synaptic Plasticity\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMagnesium L-threonate (MgT) elevates brain Mg²⁺ concentrations, leading to enhanced learning abilities, working memory, and long-term potentiation in rat models, correlated with increased synaptic density in hippocampal subregions [3].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eNeuroprotection in Alzheimer’s Models\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIn APPswe\/PS1dE9 transgenic mice, MgT treatment reduced Aβ plaque burden, prevented synapse loss, and rescued memory deficits by stabilizing NMDA-receptor–CREB signaling even in late-stage pathology [4].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eReferences\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cspan\u003eHansen HH et al. Tesofensine induces appetite suppression and weight loss with reversal of low forebrain dopamine levels in the diet-induced obese rat. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003ePharmacol Biochem Behav.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2013;110:265–271. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23932919\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/23932919\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eMoloney MA et al. Two weeks taurine supplementation reverses endothelial dysfunction in young male type 1 diabetics. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eDiab Vasc Dis Res.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2010;7(4):300–310. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20667936\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/20667936\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e\/\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eSlutsky I et al. Enhancement of learning and memory by elevating brain magnesium. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eNeuron.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2010;65(2):165–177. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20152124\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/20152124\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eLiu G et al. Elevation of brain magnesium prevents and reverses cognitive deficits and synaptic loss in Alzheimer’s disease mouse model. \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eJ Neurosci.\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e 2013;33(10):3815–3827. \u003c\/span\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23658180\/\" target=\"_blank\"\u003e\u003cspan\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/23658180\/\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003eLabel--\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable style=\"width: 99.9363%; height: 137.156px;\" border=\"1\" dir=\"ltr\" cellpadding=\"0\" cellspacing=\"0\"\u003e\n\u003ccolgroup\u003e \u003ccol style=\"width: 57.6997%;\" width=\"199\"\u003e \u003ccol style=\"width: 42.3642%;\" width=\"117\"\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 58.7812px;\"\u003e\n\u003ctd style=\"height: 58.7812px;\" colspan=\"2\"\u003e\u003cstrong\u003eSupplement Facts\u003cbr\u003eServing Size: 2 Capsules\u003cbr\u003eServings per Container: 30\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cstrong\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003eTaurine\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e500 mcg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003eMagnesium L-threonate\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e350 mcg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003eTesofensine\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e\u003cspan\u003e250 mcg\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003eDosage--\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eStore in a dry and dark place at room temperature, out of reach of small children.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947441438875,"sku":"SUPP-BIOFLOW","price":19437.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/SUPP-BIOFLOW-bioflow-RET.jpg?v=1770932687"},{"product_id":"biogutpro-biolongevity-labs","title":"BioGutPro x 60 Vegetable Capsules","description":"\u003cp\u003eDescription-- \u003cstrong\u003eBioGutPro - Advanced Gut Barrier and Regenerative Complex\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eExploring Intestinal Integrity, Inflammation Modulation, and Tissue Repair\u003c\/p\u003e\n\u003cp\u003eBioGutPro is a next-generation research formulation designed to assist investigators studying gut barrier function, regenerative processes, and localized inflammation. It combines seven complementary bioactive compounds - BPC-157, KPV, N-Acetyl Larazotide, GHK-Cu, CoreBiome® Tributyrin, Sodium Bicarbonate, and Zinc L-Carnosine - to create a synergistic model for exploring mucosal protection and intestinal healing.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey Components of BioGutPro\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157 (1000 mcg per serving*)\u003c\/strong\u003e – Studied for its potential to support tissue repair, angiogenesis, and gut lining protection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKPV (500 mcg per serving*)\u003c\/strong\u003e – A tripeptide noted for modulating inflammatory responses and supporting immune balance in gut tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eN-Acetyl Larazotide (500 mcg per serving*)\u003c\/strong\u003e – Investigated for its role in reinforcing tight junctions and reducing intestinal permeability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu (2 mg per serving*)\u003c\/strong\u003e – A copper-binding peptide that stimulates collagen synthesis and supports tissue regeneration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCoreBiome® Tributyrin (400 mg per serving*)\u003c\/strong\u003e – A direct source of butyrate, nourishing colonocytes and promoting mucosal integrity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium Bicarbonate (150 mg per serving*)\u003c\/strong\u003e – Functions as a metabolic buffer, supporting optimal pH balance for nutrient absorption.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eZinc L-Carnosine (100 mg per serving*)\u003c\/strong\u003e – Provides antioxidant and gut-supportive properties, aiding mucosal repair.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003e*Serving size = 2 capsules\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Focus Areas\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGut barrier integrity and tight junction regulation\u003c\/li\u003e\n\u003cli\u003eInflammation modulation and cytokine balance\u003c\/li\u003e\n\u003cli\u003eTissue regeneration and collagen synthesis\u003c\/li\u003e\n\u003cli\u003eNutrient absorption and mucosal nourishment\u003c\/li\u003e\n\u003cli\u003eOxidative stress reduction and antioxidant support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynergistic Potential\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTogether, BioGutPro’s seven bioactive compounds create a comprehensive research model:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBPC-157 accelerates cellular repair and regeneration.\u003c\/li\u003e\n\u003cli\u003eKPV modulates inflammatory signaling.\u003c\/li\u003e\n\u003cli\u003eN-Acetyl Larazotide strengthens gut barrier function.\u003c\/li\u003e\n\u003cli\u003eGHK-Cu supports collagen synthesis and tissue remodeling.\u003c\/li\u003e\n\u003cli\u003eCoreBiome® Tributyrin nourishes colonocytes and balances the microbiome.\u003c\/li\u003e\n\u003cli\u003eSodium Bicarbonate maintains optimal gut pH.\u003c\/li\u003e\n\u003cli\u003eZinc L-Carnosine reinforces mucosal defense and repair.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis synergy provides a unique opportunity to study gut healing, inflammation modulation, and regenerative processes in preclinical models.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBPC-157 and Gastrointestinal Healing -\u003c\/b\u003e BPC-157 is a synthetic peptide investigated for its regenerative and anti-inflammatory properties. Research suggests that it supports gastrointestinal repair by promoting angiogenesis and stimulating fibroblast activity. In preclinical models, BPC-157\u003cspan\u003e has shown promise in protecting the gastric mucosa, enhancing gut barrier integrity, and promoting collagen synthesis [1,2].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eKPV (Lys-Pro-Val) and Inflammation Modulation -\u003c\/b\u003e KPV\u003cspan\u003e is a tripeptide exhibiting notable anti-inflammatory effects. Studies indicate that KPV can reduce pro-inflammatory cytokines in gastrointestinal settings. Its capacity to modulate immune pathways and potentially mitigate inflammatory responses makes it an intriguing candidate for research on chronic gut inflammation [3].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eN-Acetyl Larazotide and Tight Junction Regulation - \u003c\/b\u003eN-Acetyl Larazotide\u003cspan\u003e (often referred to simply as larazotide) is a peptide that modulates tight junction protein assembly, thereby reducing intestinal permeability. Early-phase investigations (including clinical trials in celiac disease) have shown that by stabilizing the gut barrier, larazotide may lower the translocation of toxins and pathogens [4,5].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eGHK-CU and Tissue Regeneration - \u003c\/b\u003eGHK-CU\u003cspan\u003e, a copper-binding peptide, is extensively studied for its role in tissue repair and anti-inflammatory pathways. It can stimulate collagen synthesis, aid in wound healing, and lower oxidative stress. Laboratory models suggest that GHK-Cu supports mucosal recovery, making it a valuable tool in examining gut tissue regeneration [6].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCoreBiome® Tributyrin and Colonocyte Energy Supply - \u003c\/b\u003eCoreBiome® Tributyrin\u003cspan\u003e is a specialized triglyceride form of butyric acid supplying a direct source of butyrate - an essential short-chain fatty acid for colonocyte health.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSodium Bicarbonate and pH Optimization - \u003c\/b\u003eSodium bicarbonate\u003cspan\u003e serves as a metabolic buffer, critical for preserving optimal pH within the gastrointestinal tract. By countering excessive acidity, it supports mucosal integrity and potentially improves nutrient uptake. This buffering activity is essential for a favorable environment for tissue repair and enzymatic function [7].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eZinc L-Carnosine and Mucosal Protection - \u003c\/b\u003eZinc L-carnosine\u003cspan\u003e is a chelated compound shown to accelerate the repair of gastric and intestinal lining and to possess antioxidant attributes. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSynergistic Effects in BioGutPro\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eBioGutPro\u003cspan\u003e harnesses the complementary actions of its core components to create a broad-spectrum research model for gut healing:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eBPC-157\u003c\/b\u003e\u003cspan\u003e drives rapid tissue repair.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eKPV\u003c\/b\u003e\u003cspan\u003e modulates inflammation.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eN-Acetyl Larazotide\u003c\/b\u003e\u003cspan\u003e fortifies tight junctions.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eGHK-CU\u003c\/b\u003e\u003cspan\u003e facilitates regeneration and reduces oxidative stress.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eCoreBiome® Tributyrin\u003c\/b\u003e\u003cspan\u003e supplies key nutrients for colonocyte energy.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSodium Bicarbonate\u003c\/b\u003e\u003cspan\u003e balances pH for optimal function.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eZinc L-Carnosine\u003c\/b\u003e\u003cspan\u003e safeguards the gut lining and aids in repair.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eReferenced Citations\u003c\/b\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cp\u003eSikiric P, Seiwerth S, Rucman R, et al. (2018). Stable gastric pentadecapeptide BPC 157: vascular recruitment and therapeutic potential in gastrointestinal tract injuries. \u003ci\u003eCurrent Pharmaceutical Design\u003c\/i\u003e, 24(18), 1990–2001.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSeiwerth S, Brcic L, Klicek R, et al. (2014). Stable gastric pentadecapeptide BPC 157: an update on the development of a wound-healing agent. \u003ci\u003eExpert Opinion on Biological Therapy\u003c\/i\u003e, 14(10), 1371–1381.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCatania A, Gatti S, Colombo G, Lipton JM. (2004). Targeting melanocortin receptors as a novel strategy to control inflammation. \u003ci\u003ePharmacological Reviews\u003c\/i\u003e, 56(1), 1–29.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eKelly CP, Green PH, Murray JA, et al. (2013). Safety, tolerability, and effects on markers of intestinal permeability of larazotide acetate in celiac disease: a phase I randomized trial. \u003ci\u003eAlimentary Pharmacology \u0026amp; Therapeutics\u003c\/i\u003e, 38(6), 659–670.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eLevy C, Zoratti EM, et al. (2021). Larazotide acetate for regulating tight junction integrity: a potential therapy for celiac disease. \u003ci\u003eGastroenterology \u0026amp; Hepatology\u003c\/i\u003e, 17(3), 125–134.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003ePickart L. (2008). The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: a hypothesis. \u003ci\u003eClinical Interventions in Aging\u003c\/i\u003e, 3(2), 329–336.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eMcNaughton LR, Siegler J, Midgley A. (2008). Ergogenic effects of sodium bicarbonate. \u003ci\u003eCurrent Sports Medicine Reports\u003c\/i\u003e, 7(4), 230–236.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eLabel--\u003c\/p\u003e\n\u003ch3\u003e\u003cb\u003eMolecular Structure and Data\u003c\/b\u003e\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cb\u003eCompound\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cb\u003eMolecular Formula\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cb\u003eCAS Number\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cb\u003eBPC-157\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003eC₆₂H₉₈N₁₆O₂₂\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e137525-51-0\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e1419.54 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cb\u003eKPV (Lys-Pro-Val)\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003eC₁₆H₃₀N₄O₄\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e67727-97-3\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e342.43 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cb\u003eN-Acetyl Larazotide\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003eC₃₄H₅₉N₉O₁₂\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e881851-50-9\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e785.89 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cb\u003eGHK-Cu\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003eC₁₄H₂₀N₆O₄Cu\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e18317-00-8\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e397.70 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cb\u003eCoreBiome® Tributyrin\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003eC₁₅H₂₆O₆\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e2802-18-6\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e302.40 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cb\u003eSodium Bicarbonate\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003eNaHCO₃\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e144-55-8\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e84.01 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cb\u003eZinc L-Carnosine\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003eC₉H₁₂N₄O₃Zn\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e107667-60-7\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan\u003e289.61 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003cp\u003eDosage--\u003cstrong\u003eFor Research Purposes Only\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv data-widget_type=\"text-editor.default\" data-e-type=\"widget\" data-element_type=\"widget\" data-id=\"610a9cdc\" class=\"elementor-element elementor-element-610a9cdc elementor-widget elementor-widget-text-editor\"\u003e\n\u003cdiv data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\" class=\"ql-block\"\u003e\u003cspan\u003eThis content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\" class=\"ql-block\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\" class=\"ql-block\"\u003e\u003cspan\u003eStore in a dry and dark place at room temperature, out of reach of small children.\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947442389147,"sku":"SUPP-BGP","price":33328.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/SUPP-BGP-biogutpro-RET.jpg?v=1770932688"},{"product_id":"biomind-biolongevity-labs","title":"BioMind X 60 Vegetable Capsules","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003e\u003cstrong\u003eBioMind - Advanced Neurocognitive Research Complex\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eExploring Cognitive Function, Neuroprotection, and Synaptic Plasticity\u003c\/p\u003e\n\u003cp\u003eBioMind is a three-in-one research formulation developed to investigate pathways of neuroplasticity, cognitive resilience, and brain health in preclinical settings. It combines J-147, Dihexa, and Noopept - three complementary neuroactive compounds that together provide a unique framework for studying neural regeneration and cognitive performance.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey Components of BioMind\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eJ-147 (10mg per serving*):\u003c\/strong\u003e A neurotrophic compound studied for its ability to modulate mitochondrial function, increase BDNF, and support resilience against oxidative stress.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDihexa (10mg per serving*):\u003c\/strong\u003e A synaptogenic agent that promotes neural connectivity and repair, mimicking natural neurotrophic factors.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNoopept (10mg per serving*):\u003c\/strong\u003e A dipeptide nootropic that supports neurotransmission, memory formation, and neuronal protection.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003e*Serving size = 2 capsules\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Focus Areas\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eJ-147:\u003c\/strong\u003e Investigated for mitochondrial modulation, neuroprotection, and pathways linked to longevity and cognitive resilience.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDihexa:\u003c\/strong\u003e Explored for synaptogenesis, neural repair, and enhanced long-term potentiation (LTP).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNoopept:\u003c\/strong\u003e Studied for its role in neurotransmission, neuroprotection, and cognitive support.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynergistic Potential\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTogether, J-147, Dihexa, and Noopept create a multi-target research platform:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eJ-147 enhances mitochondrial function and BDNF expression.\u003c\/li\u003e\n\u003cli\u003eDihexa promotes synaptic repair and connectivity.\u003c\/li\u003e\n\u003cli\u003eNoopept amplifies neurotransmission efficiency and memory processes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis synergy provides a valuable opportunity to study mechanisms of neurodegeneration, cognitive enhancement, and neuronal repair in preclinical models.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eJ147 and Neuroprotection\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eJ147 is a synthetic compound designed to combat neurodegenerative diseases, particularly Alzheimer’s disease. It has demonstrated the ability to reverse cognitive impairment in aged Alzheimer’s disease mouse models by enhancing memory and synaptic plasticity [1]. Further studies indicate that J147 improves mitochondrial function and reduces markers of brain aging, suggesting its potential as a therapeutic agent for neurodegenerative conditions [2].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eDihexa and Synaptic Growth\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDihexa is an angiotensin IV analog known for its potent neurogenic and synaptogenic effects. Research has shown that Dihexa binds with high affinity to hepatocyte growth factor (HGF), promoting synaptogenesis and enhancing cognitive function in animal models of Alzheimer’s disease [3]. In APP\/PS1 mouse models, Dihexa administration rescued cognitive impairment and recovered memory via the PI3K\/AKT signaling pathway [4].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eNoopept and Cognitive Enhancement\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eNoopept is a synthetic nootropic compound recognized for its cognitive-enhancing properties. Studies have demonstrated that Noopept improves memory retention and learning capacity in animal models, suggesting its potential in addressing cognitive decline associated with aging and neurodegenerative diseases [5]. Its mechanisms include modulation of glutamatergic transmission and increased expression of neurotrophic factors, which contribute to its neuroprotective and cognitive-enhancing effects [5].\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cb\u003eSynergistic Effects of J147, Dihexa, and Noopept\u003c\/b\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBioMind’s unique formulation combines J147’s neuroprotective properties, Dihexa’s synaptogenic effects, and Noopept’s cognitive enhancement, creating a comprehensive approach to support brain health and function. This synergistic combination offers a multifaceted strategy for promoting neuronal resilience and cognitive performance, addressing synaptic loss, cognitive decline, and neuronal damage concurrently.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eReferenced Citations\u003c\/b\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cspan\u003eChen, Q., et al. (2013). “The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer’s disease mice.” \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eAlzheimer’s Research \u0026amp; Therapy\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e, 5, 25.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eCurrais, A., et al. (2019). “Elevating acetyl-CoA levels reduces aspects of brain aging.” \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eeLife\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e, 8, e47866.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eBenoist, C. C., et al. (2014). “The procognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor\/c-Met system.” \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eJournal of Pharmacology and Experimental Therapeutics\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e, 351(2), 390–402.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eSun, X., et al. (2021). “AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP\/PS1 Mouse via the PI3K\/AKT Signaling Pathway.” \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eFrontiers in Aging Neuroscience\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e, 13, 745.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eOstrovskaya, R. U., et al. (2014). “Neuroprotective properties of Noopept in experimental models of cognitive impairment.” \u003ci style=\"font-size: 0.875rem;\"\u003eJournal of Neural Transmission\u003c\/i\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003e, 121(8), 957–965.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cbr\u003e\u003cbr\u003eLabel-- \u003cb\u003eMolecular Structure and Data\u003c\/b\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 99.9363%; height: 137.156px;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003cth style=\"width: 24.8312%; height: 19.5938px;\"\u003eProperty\u003c\/th\u003e\n\u003cth style=\"width: 74.8489%; height: 19.5938px;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.8312%; height: 19.5938px;\"\u003e\u003cstrong\u003ePeptide\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.8489%; height: 19.5938px;\"\u003eJ-147\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 24.8312%; height: 39.1875px;\"\u003e\u003cstrong\u003eChemical Name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.8489%; height: 39.1875px;\"\u003e\u003cspan\u003eN-(2,4-dimethylphenyl)-2,2,2-trifluoro-N’-(3-methoxybenzyl)hydrazine\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.8312%; height: 19.5938px;\"\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.8489%; height: 19.5938px;\"\u003e\u003cspan\u003eC₁₈H₁₇F₃N₂O₂\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.8312%; height: 19.5938px;\"\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.8489%; height: 19.5938px;\"\u003e\u003cspan\u003e350.34 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.8312%; height: 19.5938px;\"\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.8489%; height: 19.5938px;\"\u003e\u003cspan\u003e1146963-51-0\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable style=\"width: 99.9363%; height: 107.969px;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003cth style=\"width: 24.9038%; height: 19.5938px;\"\u003eProperty\u003c\/th\u003e\n\u003cth style=\"width: 74.7743%; height: 19.5938px;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.9038%; height: 19.5938px;\"\u003e\u003cstrong\u003ePeptide\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.7743%; height: 19.5938px;\"\u003eDihexa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"width: 24.9038%; height: 10px;\"\u003e\u003cstrong\u003eChemical Name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.7743%; height: 10px;\"\u003e\u003cspan\u003eN-hexanoic-Tyr-Ile-(6)-aminohexanoic amide\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.9038%; height: 19.5938px;\"\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.7743%; height: 19.5938px;\"\u003e\u003cspan\u003eC₂₇H₄₄N₄O₅\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.9038%; height: 19.5938px;\"\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.7743%; height: 19.5938px;\"\u003e\u003cspan\u003e504.7 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.9038%; height: 19.5938px;\"\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.7743%; height: 19.5938px;\"\u003e\u003cspan\u003e1401708-83-5\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"width: 99.9363%; height: 107.969px;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003cth style=\"width: 24.9038%; height: 19.5938px;\"\u003eProperty\u003c\/th\u003e\n\u003cth style=\"width: 74.7743%; height: 19.5938px;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.9038%; height: 19.5938px;\"\u003e\u003cstrong\u003ePeptide\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.7743%; height: 19.5938px;\"\u003eNoopept\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"width: 24.9038%; height: 10px;\"\u003e\u003cstrong\u003eChemical Name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.7743%; height: 10px;\"\u003e\u003cspan\u003eN-phenylacetyl-L-prolylglycine ethyl ester\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.9038%; height: 19.5938px;\"\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.7743%; height: 19.5938px;\"\u003e\u003cspan\u003eC₁₇H₂₂N₂O₄\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.9038%; height: 19.5938px;\"\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.7743%; height: 19.5938px;\"\u003e\u003cspan\u003e318.4 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.9038%; height: 19.5938px;\"\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 74.7743%; height: 19.5938px;\"\u003e\u003cspan\u003e157115-85-\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003eDosage--\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eStore in a dry and dark place at room temperature, out of reach of small children.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947443503259,"sku":"SUPP-BIOMIND","price":38671.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/SUPP-BIOMIND-biomind-RET.jpg?v=1770932872"},{"product_id":"shredx-biolongevity-labs","title":"SHREDX x 60 Vegetable Capsules","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003e\u003cstrong\u003eSHREDX – Research Blend for Metabolic Optimization and Endurance Support\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSHREDX is a specialized formulation designed for researchers exploring outcomes related to endurance, metabolic efficiency, and fat oxidation. This advanced blend combines three distinct research compounds, each contributing to the study of energy utilization and body composition.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey Components of SHREDX\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSLU-PP 332: \u003c\/strong\u003eSupports fat metabolism and energy utilization in preclinical models; shown to mimic some metabolic benefits of exercise while maintaining appetite balance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGW-501516 (Cardarine):\u003c\/strong\u003e Activates PPAR delta receptors, promoting efficient energy use and endurance-related outcomes in research settings.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLipotropin HCL-AOD 9604:\u003c\/strong\u003e Investigated for its role in supporting fat breakdown and preserving lean body mass, with potential benefits for metabolic balance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe SHREDX Advantage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCombines three complementary compounds for metabolic and endurance research\u003c\/li\u003e\n\u003cli\u003eDesigned to support investigations into fat oxidation, energy efficiency, and lean body preservation\u003c\/li\u003e\n\u003cli\u003eProvides a synergistic approach to studying advanced metabolic pathways\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Insights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSLU-PP-332 has been shown to help subjects lose significant body fat without affecting appetite [1] and mimic the metabolic benefits of exercise [2], while supporting cardiovascular health [4] and improved insulin sensitivity [5]\u003c\/li\u003e\n\u003cli\u003eCardarine activates PPAR delta receptors, leading to more efficient energy utilization [3]\u003c\/li\u003e\n\u003cli\u003eAOD9604 mimics the fat-burning and insulin sensitivity promoting effects of human growth hormone effects [5]\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e[1] \u003ca class=\"txt-link\" href=\"https:\/\/www.eurekalert.org\/news-releases\/1002687\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/www.eurekalert.org\/news-releases\/1002687\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e[2] \u003ca class=\"txt-link\" href=\"https:\/\/www.technologynetworks.com\/drug-discovery\/news\/exercise-mimicking-drug-helps-mice-lose-weight-and-boost-endurance-379473\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/www.technologynetworks.com\/drug-discovery\/news\/exercise-mimicking-drug-helps-mice-lose-weight-and-boost-endurance-379473\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e[3] \u003ca class=\"txt-link\" href=\"https:\/\/jpet.aspetjournals.org\/content\/early\/2023\/09\/22\/jpet.123.001733\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/jpet.aspetjournals.org\/content\/early\/2023\/09\/22\/jpet.123.001733\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e[4] \u003ca class=\"txt-link\" href=\"https:\/\/www.labroots.com\/trending\/cardiology\/26023\/unlocking-potential-exercise-pill-err-agonist-slu-pp-332\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/www.labroots.com\/trending\/cardiology\/26023\/unlocking-potential-exercise-pill-err-agonist-slu-pp-332\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e[5] \u003ca href=\"https:\/\/news.ufl.edu\/2023\/09\/exercise-mimicking-drug\/\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/news.ufl.edu\/2023\/09\/exercise-mimicking-drug\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003eLabel--\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable border=\"1\" dir=\"ltr\" cellpadding=\"0\" cellspacing=\"0\" style=\"width: 74.5223%; height: 88.3752px;\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"199\" style=\"width: 51.7572%;\"\u003e \u003ccol width=\"117\" style=\"width: 48.3067%;\"\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd colspan=\"2\" style=\"height: 19.5938px; text-align: center;\"\u003e\u003cstrong\u003eSHREDX x 60 Vegetable Capsules\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\u003cstrong\u003ePeptides\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center; height: 19.5938px;\"\u003e\u003cstrong\u003eAmount per Serving\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003eSLU-PP-332\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e275 mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"height: 10px;\"\u003eGW501516\u003c\/td\u003e\n\u003ctd style=\"height: 10px; text-align: center;\"\u003e5000 mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003eLIPOTROPIN HCL-AOD 9604\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; text-align: center;\"\u003e100 mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003eDosage--\u003cbr\u003e\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eStore in a dry and dark place at room temperature, out of reach of small children.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947444650139,"sku":"SRDX1","price":31192.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/SRDX1-shredx-RET.jpg?v=1770932688"},{"product_id":"bioretina-a-11-retina-peptide-bioregulator-visoluten-biolongevity-labs","title":"BioRetina A-11 Retina Peptide Bioregulator (Visoluten) x 20 Capsules","description":"\u003cp\u003eDescription--\u003c!--StartFragment --\u003e\u003cstrong\u003eBioRetina® – A-11 Retina Peptide Bioregulator (Visoluten)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eNatural Peptide Complex to Support Eye Health and Visual Comfort\u003c\/p\u003e\n\u003cp\u003eBioRetina® (A-11) is a dietary supplement featuring natural peptides derived from eye tissues, formulated to help maintain the healthy function of the retina, cornea, and ocular blood vessels. Designed to complement modern lifestyles, BioRetina supports visual performance and comfort in today’s digital age.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy Choose BioRetina®?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSupports the normal function of retinal and other eye tissues\u003c\/li\u003e\n\u003cli\u003ePromotes healthy protein synthesis within eye cells\u003c\/li\u003e\n\u003cli\u003eContributes to the maintenance of visual function, especially with age-related changes\u003c\/li\u003e\n\u003cli\u003eHelps reduce eye fatigue and discomfort from prolonged screen exposure\u003c\/li\u003e\n\u003cli\u003eAssists in regulating eye metabolism and cellular activity\u003c\/li\u003e\n\u003cli\u003eComplements conventional approaches to overall eye wellness\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe BioRetina® Advantage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNatural peptide bioregulator technology (Cytomaxes)\u003c\/li\u003e\n\u003cli\u003eWorks in harmony with the body’s own peptide systems\u003c\/li\u003e\n\u003cli\u003eMay help reduce peptide deficiency and restore cellular protein synthesis\u003c\/li\u003e\n\u003cli\u003eClean formulation with no artificial additives\u003c\/li\u003e\n\u003cli\u003eAvailable in 20- or 60-capsule packs (10-day or 30-day course)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho Can Benefit from BioRetina®\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAdults experiencing visual fatigue from extended digital device use\u003c\/li\u003e\n\u003cli\u003eIndividuals seeking to maintain healthy vision and eye comfort\u003c\/li\u003e\n\u003cli\u003eWellness-conscious users looking to support long-term ocular health\u003c\/li\u003e\n\u003cli\u003eThose aiming to complement lifestyle and nutrition with peptide-based support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003eLabel--\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable style=\"width: 99.9363%; height: 273.907px;\" border=\"1\" dir=\"ltr\" cellpadding=\"0\" cellspacing=\"0\"\u003e\n\u003ccolgroup\u003e \u003ccol style=\"width: 44.4728%;\" width=\"199\"\u003e \u003ccol style=\"width: 26.0703%;\" width=\"117\"\u003e \u003ccol style=\"width: 29.5208%;\" width=\"132\"\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 62.8854px;\"\u003e\n\u003ctd style=\"height: 62.8854px;\" colspan=\"3\"\u003e\u003cstrong\u003eSupplement Facts\u003cbr\u003eServing Size: 2 Capsules\u003cbr\u003eServings per Container: 10\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.0104px;\"\u003e\n\u003ctd style=\"height: 21.0104px; text-align: center;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 21.0104px; text-align: center;\"\u003e\u003cstrong\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 21.0104px; text-align: center;\"\u003e\u003cstrong\u003e% Daily Value\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 41.9688px;\"\u003e\n\u003ctd style=\"height: 41.9688px; text-align: left;\"\u003e\u003cspan\u003ePeptide complex A-11 (retina peptides)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 41.9688px; text-align: center;\"\u003e\u003cspan\u003e0.04 g\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 41.9688px; text-align: center;\"\u003e\u003cspan\u003e†\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 148.042px;\"\u003e\n\u003ctd style=\"height: 148.042px;\" colspan=\"3\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e†\u003c\/span\u003eDaily Value not established\u003cbr\u003e\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOther ingredients:\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003emicrocrystalline cellulose (E460, flowing agent); calcium stearate (E470, emulsifier), \u003cstrong\u003e\u003c\/strong\u003eCapsule\u003cstrong\u003e\u003cspan\u003e - \u003c\/span\u003e\u003c\/strong\u003ehydroxypropylmethylcellulose.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThis product is Gluten-free, Lactose-free, Non-GMO, Dye-free.\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003eDosage--\u003cstrong\u003eSuggested Use : \u003c\/strong\u003eFor adults, take 1-2 capsules, 1-2 times daily with meals\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eContraindications: \u003c\/strong\u003eIndividual component sensitivity, pregnancy, breastfeeding\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cstrong\u003eCaution: \u003c\/strong\u003eKEEP OUT OF REACH OF CHILDREN. Store in a dry, dark place at temperatures between +2°C and +25°C\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eShelf life:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e3 years from production date\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947445698715,"sku":"BR-A11-20","price":13456.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/BR-A11-20-bioretina-a-11-retina-peptide-bioregulator-visoluten-RET.jpg?v=1770933379"},{"product_id":"biosculpt-thermogenic-cream-biolongevity-labs","title":"BioSculpt Thermogenic Cream X 50 gm","description":"\u003cp\u003eDescription-- \u003cstrong\u003eUnlock Your Body’s Sculpting Potential with BioSculpt\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe Advanced Peptide Bioregulator Cream for a Lean, Defined Physique\u003c\/p\u003e\n\u003cp\u003eImagine revealing the physique you’ve always envisioned—lean, sculpted, and confident. BioSculpt works in harmony with your body’s natural metabolic rhythm, supporting fat breakdown, enhancing thermogenesis, and promoting skin firmness to help you refine muscle definition and achieve a more toned appearance.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe BioSculpt Advantage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003ePeptide bioregulator technology - harmonizes metabolic activity\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eThermogenic botanicals - natural support for fat metabolism\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eDeep tissue absorption - effective delivery to targeted areas\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eClean formulation - no artificial colors or additives\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eGentle and suitable for consistent use\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy BioSculpt is Your Ultimate Body-Shaping Partner\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eSupports natural fat metabolism and energy utilization\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eEncourages thermogenesis to complement active lifestyles\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eHelps reduce excess water retention for a leaner look\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003ePromotes skin elasticity and firmness in targeted areas\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eComplements exercise by enhancing nutrient and oxygen delivery\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eDesigned for daily use to support ongoing body-shaping goals\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe Science Behind BioSculpt\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBioSculpt’s advanced formulation blends peptide bioregulators with thermogenic botanicals to naturally support your body’s sculpting process:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eTargets stubborn areas to encourage localized fat metabolism\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBoosts thermogenesis in zones like abs, thighs, and glutes\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eHelps refine muscle definition by reducing subcutaneous fat appearance\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003ePromotes skin tightening as fat cells shrink\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSupports metabolic efficiency for improved caloric utilization\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho Can Benefit from BioSculpt\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eFitness enthusiasts refining muscle tone\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAthletes and performers maintaining a lean, defined physique\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eWellness-focused individuals seeking natural support for body-shaping goals\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAesthetic-conscious users looking to complement diet and exercise\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003eLabel--\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable style=\"width: 99.9363%; height: 117.563px;\" cellspacing=\"0\" cellpadding=\"0\" dir=\"ltr\" border=\"1\"\u003e\n\u003ccolgroup\u003e \u003ccol style=\"width: 38.0497%;\" width=\"199\"\u003e \u003ccol style=\"width: 22.3709%;\" width=\"117\"\u003e \u003ccol style=\"width: 25.239%;\" width=\"132\"\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"text-align: center; height: 19.5938px;\" colspan=\"3\"\u003e\u003cstrong\u003eBioSculpt Thermogenic Cream\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 97.9688px;\"\u003e\n\u003ctd style=\"height: 97.9688px;\" colspan=\"3\"\u003e\n\u003cstrong\u003eIngredients: \u003c\/strong\u003ePurified water, Caffeine, Neovitin, Olive oil, Jojoba oil, Glycerol, DEG Stearate, Capsicum Annuum Extract, Lanolin, Stearin, Emulsion Wax, Sodium Hyaluronate, Methylparaben, Propylparaben, Imidazolidinyl Urea, Fucus Extract, Triethanolamine, Citric Acid, Acrylates and C-10-30 Alkyl acrylate, Copolymer, Fragrance composition, Methylisothiazolinone, Methylchloroisothiazolinone, Thiazone, Nerolidol, Oleic acid, \u003cspan\u003eStearyl Methacrylate, Paraffinum Liquidum, Stearyl Alcohol, Cetyl Palmitate, Cetyl Alcohol, Glyceryl Stearate, Sodium Lauryl Sulfate, Lecithin, Methylparaben, Peptides AK-1, Peptides AK-3, Peptides AK-7, Peptides AK-8, Peptides AK-9, Peptides AK-12\u003c\/span\u003e\u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003eDosage-- \u003cstrong\u003eHow to use BioSculpt\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli aria-level=\"1\"\u003e\n\u003cb\u003ePrepare the area\u003c\/b\u003e\u003cspan\u003e – Ensure the skin is \u003c\/span\u003eclean, dry, and free from hair or damage.\u003c\/li\u003e\n\u003cli aria-level=\"1\"\u003e\n\u003cb\u003eApply the cream\u003c\/b\u003e\u003cspan\u003e – Massage a small, fingernail-sized amount into \u003c\/span\u003etargeted fat areas (e.g., lower abs, thighs, glutes).\u003c\/li\u003e\n\u003cli aria-level=\"1\"\u003e\n\u003cb\u003eUse before fasted cardio\u003c\/b\u003e\u003cspan\u003e – For best results, apply before \u003c\/span\u003emorning cardio or training.\u003c\/li\u003e\n\u003cli aria-level=\"1\"\u003e\n\u003cb\u003eUse consistently\u003c\/b\u003e\u003cspan\u003e – Apply \u003c\/span\u003eonce daily, or twice daily\u003cspan\u003e for enhanced fat-burning effects.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eCautions: \u003c\/strong\u003eFor external use only. Do not apply to open wound, damaged skin, or other sensitive areas. Apply to stubborn body fat resistant sites like the abdomen, thigs, low back, love handles, glutes and hamstrings. It is recommended to apply at least once a day and up to 2 times (preferably prior to exercise) to enhance localized thermogenesis and stubborn fat burning.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947446943899,"sku":"TOP-BS","price":20500.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/TOP-BS-biosculpt-thermogenic-cream-RET.jpg?v=1770933287"},{"product_id":"bioregenix-recovery-cream-biolongevity-labs","title":"BioRegenix Recovery Cream","description":"\u003cp\u003eDescription-- \u003c!--StartFragment --\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cstrong\u003eUnlock Your Body’s Healing Power with BioRegenix\u003c\/strong\u003e\u003cbr\u003eThe Advanced Peptide Bioregulator Cream for Rapid Soft Tissue Repair.\u003c\/p\u003e\n\u003cp\u003eImagine life without constant aches, strains, or slow recovery. BioRegenix works with your body’s natural healing systems to accelerate repair, restore mobility, and keep you performing at your best.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy Choose BioRegenix?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRelieves muscle fatigue and joint discomfort\u003c\/li\u003e\n\u003cli\u003eReduces swelling, bruising, and fluid retention\u003c\/li\u003e\n\u003cli\u003eAccelerates tendon and ligament recovery\u003c\/li\u003e\n\u003cli\u003eProvides effective pain relief and comfort\u003c\/li\u003e\n\u003cli\u003eSafe, gentle, and suitable for daily use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eThe BioRegenix Advantage:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBreakthrough peptide bioregulator technology\u003c\/li\u003e\n\u003cli\u003eEnhanced cellular recovery for long-term tissue health\u003c\/li\u003e\n\u003cli\u003eDeep tissue penetration for maximum absorption\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003eLabel--\u003c\/p\u003e\n\u003ctable width=\"100%\" style=\"height: 29.5938px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"height: 10px; text-align: center;\"\u003e\u003cstrong\u003e BioRegenix Recovery Cream\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px;\"\u003e\n\u003cstrong\u003eIngredients:\u003c\/strong\u003e Purified water, Neovitin, Olive oil, Soybean Oil, Propylene Glycol, Glycerol Monostearate, Emulsion Wax, PEG-40 Hydrogenated Castor oil, Ethylhexyl cocoate, Stearin, Cetearyl Alcohol, Cyclomethicone, Dimethicone, Panthenol, Zolidinyl Urea, Triethanolamine, Phenoxyethanol w\/ Ethylhexylglycerin, Bisabolol, Perfume Composition, Butylhydroxytoluene, Citric Acid, Thiazone, Nerolidol, Oleic Acid, Stearyl Methacrylate, Paraffinum, Mineral Oil, Stearyl Alcohol, Cetyl Palmitate, Cetyl Alcohol, Glyceryl Stearate, Sodium Lauryl Sulfate, Lecithin, Methylparaben, Peptides AK-1, Peptides AK-3, Peptides AK-7, Peptides AK-8, Peptides AK-9, Peptides AK-12\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eDosage-- \u003cstrong\u003eHow to Use:\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eClean and dry the affected area.\u003c\/li\u003e\n\u003cli\u003eApply a small amount of cream and massage gently.\u003c\/li\u003e\n\u003cli\u003eUse once daily, or up to three times per day for acute injuries.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cstrong\u003eCautions: \u003c\/strong\u003eFor external use only. Do not apply to open wounds, damaged skin, or other sensitive areas. Use Bioregenix for soft tissue injuries, including aches, sprains, strains, and performance and age related muscle pain. It is recommended to apply at least once a day and up to 3 times depending on the acute nature of injury.\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947448058011,"sku":"TOP-BR","price":22642.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/TOP-BR-bioregenix-recovery-cream-RET.jpg?v=1770933078"},{"product_id":"klow-blend-ghk-cu-bpc-157-tb-500-kpv-80mg-biolongevity-labs","title":"KLOW Blend (GHK-Cu, BPC-157, TB-500, KPV) X 80mg","description":"\u003cp\u003eDescription-- \u003c!--StartFragment --\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cstrong\u003eLaboratory Research Overview\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLaboratory investigations highlight synergistic mechanisms across cellular repair, vascular formation, and inflammatory modulation—providing valuable tools for in vitro research applications.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAngiogenesis and Vascular Formation\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157:\u003c\/strong\u003e Upregulates VEGFR2 expression without altering VEGF-A levels, activating the VEGFR2–Akt–eNOS signaling cascade in endothelial cell cultures [1].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu:\u003c\/strong\u003e At nanomolar concentrations, increased VEGF and bFGF expression by 230% in irradiated fibroblasts [2]; liposomal delivery enhanced HUVEC proliferation by 33.1% with elevated cell cycle protein expression [3].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB-500:\u003c\/strong\u003e Acts as a potent endothelial chemoattractant, stimulating 4–6-fold increases in HUVEC migration; activity observed at ~50 nM concentration via LKKTET sequence [4].\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTissue Repair and Regeneration\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu:\u003c\/strong\u003e Modulates ~31% of human genes (4,192 genes) with ≥50% expression changes, activating integrin-linked kinase pathways [5].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157:\u003c\/strong\u003e Promotes regeneration via FAK–paxillin pathway activation, increasing phosphorylation of focal adhesion proteins [6].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB-500:\u003c\/strong\u003e Sequesters G-actin in a 1:1 ratio; rat wound models showed 42–61% increased reepithelialization with enhanced collagen deposition [7].\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCollagen Synthesis and Extracellular Matrix\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu:\u003c\/strong\u003e Stimulates collagen synthesis at picomolar–nanomolar concentrations; increased decorin by 302% and glycosaminoglycan accumulation [8].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157:\u003c\/strong\u003e Enhances collagen, reticulin, and vascular formation in animal models [9].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB-500:\u003c\/strong\u003e Promotes organized collagen deposition with anti-fibrotic properties, reducing myofibroblast formation [10].\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eInflammatory Modulation\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu:\u003c\/strong\u003e Inhibits NF-κB p65 and p38 MAPK pathways, reducing ROS and cytokines TNF-α and IL-6 [2].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157:\u003c\/strong\u003e Decreases TNF-α, IL-6, IL-1β, COX-2 expression, and myeloperoxidase activity [11].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB-500:\u003c\/strong\u003e Biphasic regulation—downregulates TNF-α (6.2-fold) and IL-6 (4.1-fold), while upregulating IL-10 (8.1-fold) [12].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKPV:\u003c\/strong\u003e Inhibits NF-κB activation via IκB-α stabilization; reduces cytokine secretion in epithelial and macrophage cultures [13,14].\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNeuroprotection and Neural Mechanisms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu:\u003c\/strong\u003e Increases NGF and neurotrophins NT-3\/NT-4; improved spatial memory in aging models [15].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157:\u003c\/strong\u003e Modulates dopaminergic systems without direct receptor binding [16].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB-500:\u003c\/strong\u003e Provides neuroprotection via caspase-3 inhibition; promotes oligodendrocyte progenitor proliferation through p38 MAPK upregulation [17].\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCellular Migration and Proliferation\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB-500:\u003c\/strong\u003e G-actin sequestration drives migration; photorelease studies show directional cell turning [7].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu:\u003c\/strong\u003e Chemoattractant for macrophages, mast cells, and endothelial cells [18].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157:\u003c\/strong\u003e Regulates migration via ERK1\/2 phosphorylation; transcription factors c-Fos (4.99-fold), c-Jun (7.05-fold), Egr-1 (3.70-fold) upregulated [19].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKPV:\u003c\/strong\u003e Promotes keratinocyte and fibroblast migration; increased viability in corneal epithelial cultures [20].\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWound Healing Mechanisms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157:\u003c\/strong\u003e Accelerates repair phases including inflammation, collagen deposition, angiogenesis, and epithelial recovery [9].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu:\u003c\/strong\u003e Enhances systemic and local remodeling; collagen dressings improved contraction and antioxidant levels [5].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB-500:\u003c\/strong\u003e Promotes organized repair with anti-scarring effects; increased wound contraction (11%) and reepithelialization (42–61%) [10].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKPV:\u003c\/strong\u003e Accelerates mucosal and corneal healing; complete reepithelialization within 60 hours [14,20].\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOxidative Stress Response\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu:\u003c\/strong\u003e Reduces ROS, increases superoxide dismutase activity, quenches radicals [21].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB-500:\u003c\/strong\u003e Upregulates antioxidant enzymes Cu\/Zn-SOD and catalase [11].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157:\u003c\/strong\u003e Scavenges free radicals, normalizes NO and MDA levels, increases HO-1 and NOS-3 expression [11].\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKPV:\u003c\/strong\u003e Inhibits ROS in keratinocytes via ERK and p38 MAPK modulation [22].\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e \u003cstrong\u003eThese peptides are intended strictly for in vitro research applications. They are not for human consumption or therapeutic use\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch5\u003e\n\u003cstrong\u003e[\u003c\/strong\u003e1] M.-J. Hsieh \u003cem\u003eet al.\u003c\/em\u003e, “Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation,” Springer Science and Business Media LLC, Nov. 2016. doi: 10.1007\/s00109-016-1488-y. Available: \u003ca href=\"https:\/\/doi.org\/10.1007\/s00109-016-1488-y\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1007\/s00109-016-1488-y\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[2] Y. Dou, A. Lee, L. Zhu, J. Morton, and W. Ladiges, “The potential of GHK as an anti-aging peptide,” Ant Publishing, Mar. 2020. doi: 10.31491\/apt.2020.03.014. Available: \u003ca href=\"https:\/\/doi.org\/10.31491\/apt.2020.03.014\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.31491\/apt.2020.03.014\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[3] X. Wang \u003cem\u003eet al.\u003c\/em\u003e, “GHK‐Cu‐liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis,” Wiley, Apr. 2017. doi: 10.1111\/wrr.12520. Available: \u003ca href=\"https:\/\/doi.org\/10.1111\/wrr.12520\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1111\/wrr.12520\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[4] K. M. Malinda, A. L. Goldstein, and H. K. Kueinman, “Thymosin β            4            stimulates directional migration of human umbilical vein endothelial cells,” Wiley, May 1997. doi: 10.1096\/fasebj.11.6.9194528. Available: \u003ca href=\"https:\/\/doi.org\/10.1096\/fasebj.11.6.9194528\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1096\/fasebj.11.6.9194528\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[5] L. Pickart and A. Margolina, “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data,” MDPI AG, Jul. 2018. doi: 10.3390\/ijms19071987. Available: \u003ca href=\"https:\/\/doi.org\/10.3390\/ijms19071987\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/ijms19071987\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[6] C.-H. Chang, W.-C. Tsai, M.-S. Lin, Y.-H. Hsu, and J.-H. S. Pang, “The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration,” American Physiological Society, Mar. 2011. doi: 10.1152\/japplphysiol.00945.2010. Available: \u003ca href=\"https:\/\/doi.org\/10.1152\/japplphysiol.00945.2010\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1152\/japplphysiol.00945.2010\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[7] B. Xue, C. Leyrat, J. M. Grimes, and R. C. Robinson, “Structural basis of thymosin-β4\/profilin exchange leading to actin filament polymerization,” Proceedings of the National Academy of Sciences, Oct. 2014. doi: 10.1073\/pnas.1412271111. Available: \u003ca href=\"https:\/\/doi.org\/10.1073\/pnas.1412271111\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1073\/pnas.1412271111\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[8] F.-X. Maquart, L. Pickart, M. Laurent, P. Gillery, J.-C. Monboisse, and J.-P. Borel, “Stimulation of collagen synthesis in fibroblast cultures by the tripeptide‐copper complex glycyl‐L‐histidyl‐L‐lysine‐Cu2+,” Wiley, Oct. 1988. doi: 10.1016\/0014-5793(88)80509-x. Available: \u003ca href=\"https:\/\/doi.org\/10.1016\/0014-5793(88)80509-x\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/0014-5793(88)80509-x\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[9] S. Seiwerth \u003cem\u003eet al.\u003c\/em\u003e, “Stable Gastric Pentadecapeptide BPC 157 and Wound Healing,” Frontiers Media SA, Jun. 2021. doi: 10.3389\/fphar.2021.627533. Available: \u003ca href=\"https:\/\/doi.org\/10.3389\/fphar.2021.627533\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3389\/fphar.2021.627533\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[10] K. M. Malinda \u003cem\u003eet al.\u003c\/em\u003e, “Thymosin beta4 accelerates wound healing.,” \u003cem\u003eJournal of Investigative Dermatology\u003c\/em\u003e, vol. 113 3, pp. 364–8, 1999.\u003c\/h5\u003e\n\u003ch5\u003e[11] H. Demirtaş, A. Özer, A. K. Yıldırım, A. D. Dursun, Ş. C. Sezen, and M. Arslan, “Protective Effects of BPC 157 on Liver, Kidney, and Lung Distant Organ Damage in Rats with Experimental Lower-Extremity Ischemia–Reperfusion Injury,” MDPI AG, Feb. 2025. doi: 10.3390\/medicina61020291. Available: \u003ca href=\"https:\/\/doi.org\/10.3390\/medicina61020291\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/medicina61020291\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[12] M. A. Evans \u003cem\u003eet al.\u003c\/em\u003e, “Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing,” Springer Science and Business Media LLC, Jul. 2013. doi: 10.1038\/ncomms3081. Available: \u003ca href=\"https:\/\/doi.org\/10.1038\/ncomms3081\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1038\/ncomms3081\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[13] G. Dalmasso, L. Charrier–Hisamuddin, H. T. Thu Nguyen, Y. Yan, S. Sitaraman, and D. Merlin, “PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation,” Elsevier BV, Jan. 2008. doi: 10.1053\/j.gastro.2007.10.026. Available: \u003ca href=\"https:\/\/doi.org\/10.1053\/j.gastro.2007.10.026\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1053\/j.gastro.2007.10.026\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[14] B. Xiao \u003cem\u003eet al.\u003c\/em\u003e, “Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis,” Elsevier BV, Jul. 2017. doi: 10.1016\/j.ymthe.2016.11.020. Available: \u003ca href=\"https:\/\/doi.org\/10.1016\/j.ymthe.2016.11.020\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/j.ymthe.2016.11.020\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[15] L. Pickart, J. M. Vasquez-Soltero, and A. Margolina, “The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging: Implications for Cognitive Health,” Hindawi Limited, 2012. doi: 10.1155\/2012\/324832. Available: \u003ca href=\"https:\/\/doi.org\/10.1155\/2012\/324832\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1155\/2012\/324832\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[16] J. Vukojevic \u003cem\u003eet al.\u003c\/em\u003e, “Pentadecapeptide BPC 157 and the central nervous system,” Medknow, 2022. doi: 10.4103\/1673-5374.320969. Available: \u003ca href=\"https:\/\/doi.org\/10.4103\/1673-5374.320969\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.4103\/1673-5374.320969\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[17] S. Kim, J. Choi, and J. Kwon, “Thymosin Beta 4 Protects Hippocampal Neuronal Cells against PrP (106–126) via Neurotrophic Factor Signaling,” MDPI AG, May 2023. doi: 10.3390\/molecules28093920. Available: \u003ca href=\"https:\/\/doi.org\/10.3390\/molecules28093920\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/molecules28093920\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[18] L. Pickart, J. M. Vasquez-Soltero, and A. Margolina, “GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration,” Wiley, 2015. doi: 10.1155\/2015\/648108. Available: \u003ca href=\"https:\/\/doi.org\/10.1155\/2015\/648108\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1155\/2015\/648108\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[19] T. Huang \u003cem\u003eet al.\u003c\/em\u003e, “Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro,” Informa UK Limited, Apr. 2015. doi: 10.2147\/dddt.s82030. Available: \u003ca href=\"https:\/\/doi.org\/10.2147\/dddt.s82030\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.2147\/dddt.s82030\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[20] M. Böhm and T. Luger, “Are melanocortin peptides future therapeutics for cutaneous wound healing?,” Wiley, Feb. 2019. doi: 10.1111\/exd.13887. Available: \u003ca href=\"https:\/\/doi.org\/10.1111\/exd.13887\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1111\/exd.13887\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[21] S. Sharma, M. F. Anwar, A. Dinda, M. Singhal, and A. Malik, “In Vitro and in Vivo Studies of pH-Sensitive GHK-Cu-Incorporated Polyaspartic and Polyacrylic Acid Superabsorbent Polymer,” American Chemical Society (ACS), Nov. 2019. doi: 10.1021\/acsomega.9b00655. Available: \u003ca href=\"https:\/\/doi.org\/10.1021\/acsomega.9b00655\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1021\/acsomega.9b00655\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003ch5\u003e[22] J. Sung, S.-Y. Ju, S. Park, W.-K. Jung, J.-Y. Je, and S.-J. Lee, “Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK\/NF-κB pathway,” Elsevier BV, Aug. 2025. doi: 10.1016\/j.tice.2025.102837. Available: \u003ca href=\"https:\/\/doi.org\/10.1016\/j.tice.2025.102837\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/j.tice.2025.102837\u003c\/a\u003e\n\u003c\/h5\u003e\n\u003cp\u003eLabel--\u003c\/p\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cstrong\u003eProperty\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eGHK-Cu\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eBPC-157\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eTB-500\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eKPV\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSequence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e Gly-His-Lys.Cu.xHAc\u003c\/td\u003e\n\u003ctd\u003eGly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val\u003c\/td\u003e\n\u003ctd\u003eAc-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser\u003c\/td\u003e\n\u003ctd\u003e Lys-Pro-Val\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC₁₄H₂₃CuN₆O₄\u003c\/td\u003e\n\u003ctd\u003eC₆₂H₉₈N₁₆O₂₂\u003c\/td\u003e\n\u003ctd\u003eC₂₁₂H₃₅₀N₅₆O₇₈S\u003c\/td\u003e\n\u003ctd\u003eC₁₇H₃₂N₆O₄\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e401.91 g\/mol\u003c\/td\u003e\n\u003ctd\u003e1419.5 g\/mol\u003c\/td\u003e\n\u003ctd\u003e4963.55 g\/mol\u003c\/td\u003e\n\u003ctd\u003e384.48 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePubChem CID\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e73587\u003c\/td\u003e\n\u003ctd\u003e9941957\u003c\/td\u003e\n\u003ctd\u003e16132341\u003c\/td\u003e\n\u003ctd\u003e125672\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e89030-95-5\u003c\/td\u003e\n\u003ctd\u003e137525-51-0\u003c\/td\u003e\n\u003ctd\u003e77591-33-4\u003c\/td\u003e\n\u003ctd\u003e67727-97-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCopper peptide GHK, Cu-GHK, NSC 661251\u003c\/td\u003e\n\u003ctd\u003ePL-14736, Body-Protection Compound-157, Bepecin\u003c\/td\u003e\n\u003ctd\u003eThymosin-β4 fragment 17-23, TB-500 acetate, Ac-LKKTETQ\u003c\/td\u003e\n\u003ctd\u003eα-MSH fragment (11–13), Tripeptide KPV, Ac-KPV-NH2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eLyophilized Peptides: Our peptides are supplied in a pure, freeze-dried form with no fillers, ensuring long-term stability and integrity during cold storage. Simply reconstitute with sterile solvent before use, and store aliquots at ≤ –20 °C to protect against repeated freeze–thaw cycles.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eDosage-- \u003cstrong\u003eFor Research Purposes Only\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"elementor-element elementor-element-610a9cdc elementor-widget elementor-widget-text-editor\" data-id=\"610a9cdc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\"\u003e\n\u003cdiv class=\"ql-block\" data-block-id=\"block-32eed5f9-875e-4180-94f9-d97658bf7841\"\u003e\u003cspan\u003eThis content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947452907675,"sku":"BPC-TB5-KPV-GHK-80MG","price":30658.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/BPC-TB5-KPV-GHK-80MG-klow-blend-ghk-cu-bpc-157-tb-500-kpv-80mg-RET.jpg?v=1770933379"},{"product_id":"bpc-157-10mg-biolongevity-labs","title":"BPC-157 X 10mg","description":"\u003cp\u003eDescription-- \u003c!--StartFragment --\u003eBPC-157 is a synthetic peptide of 15 amino acids, inspired by a protective protein naturally present in human gastric juice. Its sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) makes it highly stable, even in challenging conditions like gastric acidity. While not found in isolation in nature, its parent protein is known for supporting gastrointestinal protection and repair.\u003cbr\u003eBPC-157 works through multiple pathways to encourage tissue healing, including stimulating growth hormone receptors and activating JAK2 signaling, which boosts collagen production and fibroblast activity.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cstrong\u003eLyophilized Peptides:\u003c\/strong\u003e Our peptides are freeze-dried to maintain purity and extend shelf life, with absolutely no fillers used in the process\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003cbr\u003eLabel--\u003c\/p\u003e\n\u003ctable style=\"width: 99.9363%;\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth style=\"width: 24.8312%;\"\u003eProperty\u003c\/th\u003e\n\u003cth style=\"width: 74.8489%;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24.8312%;\"\u003ePeptide Sequence\u003c\/td\u003e\n\u003ctd style=\"width: 74.8489%;\"\u003eGly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24.8312%;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"width: 74.8489%;\"\u003eC62H98N15O22\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24.8312%;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"width: 74.8489%;\"\u003e1419.5 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24.8312%;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"width: 74.8489%;\"\u003e137525-51-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24.8312%;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"width: 74.8489%;\"\u003e108101\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24.8312%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 74.8489%;\"\u003eA886440, L-Valine, glycyl-L-a-glutamyl-L-prolyl-L-prolyl-L-prolylglycyl-L-lysyl-L-prolyl-L-alanyl-L-a-aspartyl-L-a-aspartyl-L-alanylglycyl-L-leucyl- Acetate\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cstyle type=\"text\/css\"\u003e\n        td {border: 1px solid #cccccc;}\n        br {mso-data-placement: same-cell;}\n        .bold {font-weight: bold;}\n    \u003c\/style\u003e\n\u003ch3\u003e\u003cspan\u003eBPC-157 Peptide Structure\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/image\/imgsrv.fcgi?cid=108101\u0026amp;t=l\" alt=\"BPC-157 peptide structure\"\u003e\u003cbr\u003eDosage--\u003cbr\u003e\u003cstrong\u003eThis PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.\u003c\/strong\u003e\u003cspan\u003e This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.\u003c\/span\u003e\u003c\/p\u003e","brand":"Biolongevity Labs","offers":[{"title":"Default Title","offer_id":47947459887259,"sku":"BPC-10MG","price":11965.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3694\/4795\/files\/BPC-10MG-bpc-157-10mg-RET.jpg?v=1770933379"}],"url":"https:\/\/fmihealth.com\/collections\/peptides.oembed","provider":"FMI health","version":"1.0","type":"link"}